Gene Information

Name : Sfla_3844 (Sfla_3844)
Accession : YP_004924778.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 4422423 - 4423100 bp
Length : 678 bp
Strand : +
Note : KEGG: scb:SCAB_54821 two-component system reponse regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; transcriptional regulator domain-containing protein

DNA sequence : 
ATGACCCGTGTACTGCTCGCCGAGGACGACGCATCCATCTCGGAGCCACTGGCCCGCGCCCTGCGTCGAGAGGGTTACGA
GGTCGAGGTCCGCGAGGACGGACCGACCGCGCTCGACGCCGGACTCCAGGGAGGCGTCGACCTGGTCGTCCTCGACCTGG
GGCTCCCCGGCATGGACGGCCTGGAGGTCGCCAGGCGGCTGCGTGCCGACGGCCACGCCGTGCCGATCCTGGTGCTGACC
GCCCGCGCCGACGAGGTCGACACCGTCGTCGGTCTGGACGCCGGCGCCGACGACTACGTCACCAAGCCCTTCCGTCTCGC
CGAGCTCCTCGCCCGGGTCCGTGCCCTGCTGCGGCGCGGCGCGGCCGAGCCGGCCCCGCAGCCCGCCACGCACGGCGTCA
GGATCGACGTCGAGTCCCACCGTGCCTGGATGGGCGACGAGGAACTCCAGCTCACGGCGAAGGAGTTCGACCTGCTCCGG
GTCCTCGTCCGGGACGCCGGCCGGGTCGTCACCCGCGACCAGCTGATGCGTGAGGTCTGGGACACCACGTGGTGGTCCTC
CACCAAGACCCTCGACATGCACATCTCCTGGCTCCGTAAGAAGCTCGGGGACGACGCCGCCAATCCGCGGTACATCGCCA
CCGTCCGGGGCGTCGGCTTCCGGTTCGAGAAGAGCTGA

Protein sequence : 
MTRVLLAEDDASISEPLARALRREGYEVEVREDGPTALDAGLQGGVDLVVLDLGLPGMDGLEVARRLRADGHAVPILVLT
ARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRGAAEPAPQPATHGVRIDVESHRAWMGDEELQLTAKEFDLLR
VLVRDAGRVVTRDQLMREVWDTTWWSSTKTLDMHISWLRKKLGDDAANPRYIATVRGVGFRFEKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-14 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 2e-29 48
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator BAC0083 Protein 1e-19 42
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator U82965.2.orf14.gene. Protein 1e-16 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator VFG1390 Protein 3e-25 44
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator VFG1389 Protein 2e-22 43
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator VFG0596 Protein 6e-15 42
Sfla_3844 YP_004924778.1 winged helix family two component transcriptional regulator VFG0473 Protein 2e-18 41