Gene Information

Name : Sfla_3495 (Sfla_3495)
Accession : YP_004924432.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4030829 - 4033354 bp
Length : 2526 bp
Strand : +
Note : KEGG: sgr:SGR_4118 ATP-dependent Clp protease; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGTCAGGGGCAGCAGGCCCCGTCCGGGCACATCCCCTTC
ACCCCCCGGGCCAAGAAGGTCCTGGAGCTGTCGCTCCGTGAGGCCCTTCAGCTCGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTGAAGCTGGGCGCCGACCTGAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGGTACTCGGGAGGCAAGGAGGCTGCCACCGCCGGCGGCCCCGCGGAGGGC
ACGCCCTCCACGTCCCTGGTGCTCGACCAGTTCGGCCGGAATCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGT
CATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAACCCGGTGCTCATCGGTG
AGCCCGGCGTCGGCAAGACGGCTGTCGTCGAGGGCCTGGCCCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAG
GACAAGCACCTCTACACCCTCGACCTCGGTGCCCTGGTCGCCGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAA
GAAGGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACACCCTCGTGGGTGCGGGTG
CCGCCGAGGGCGCGATCGACGCCGCGAGCATCCTCAAGCCGATGCTGGCGCGGGGCGAGCTGCAGACCATCGGTGCCACG
ACGCTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCCGCGCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCC
GTCGCTGCCGCACACCATCGAGATCCTCAAGGGGCTCCGCGACCGTTACGAGGCCCACCACAGGGTCTCCATCACGGACG
AGGCGCTGGTCCAGGCCGCCACCCTGGCCGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATC
GACGAGGCCGGCTCCCGGATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCGGG
CGTCCGCCGCGACAAGGAGTCGGCGATCGACTCCCAGGACTTCGAGAAGGCAGCTTCGCTCCGCGACAAGGAGAAGCAGC
TGCTGGCGGCGAAGGCCAAGCGCGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTGGCCGAGGTCGACGGCGAGCTC
ATCGCCGAGGTCCTCGCCACCGCGACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGTCTGCTGCGCAT
GGAGGACGAGCTCCACAAGCGCGTCATCGGGCAGAAGGACGCCATCAAGGCCCTCTCGCAGGCGATCCGTCGTACGCGAG
CCGGCCTGAAGGACCCGAAGCGCCCCGGTGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACGGAGCTCTCC
AAGACGCTCGCCGAATTCCTCTTCGGTGACGAGGACGCGCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACAC
GGTTTCCCGTCTCTTCGGTTCGCCCCCCGGTTACGTGGGTTACGAAGAGGGCGGTCAGCTCACCGAGAAGGTGCGCCGTA
AGCCGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCCGATATCTTCAACTCCCTGCTCCAGATTCTGGAG
GACGGTCGTCTGACCGACTCCCAGGGTCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGGAC
CAGGGACATCTCGAAGGGCTTCAACCTGGGCTTCGCCGCCCAGGGCGACGTCAAGACGAACTACGAGCGGATGAAGGTCA
AGGTCAACGAAGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTCGACGACACGGTCGTCTTCCACCAGCTC
ACCGAGGAAGACATCATCCAGATCGTCGACCTCATGGTCGCCAAGGTGGACGAGCGCCTCAAGGACCGCGACATGGGCAT
CGAGCTCAGTGCCGAGGCCAAGTCGCTCCTGGCGAAGAAGGGCTACGACCCCGTGATGGGCGCCCGGCCGCTGCGCCGGA
CGATCCAGCGCGAGATCGAGGACATCCTCTCCGAGAAGATCCTCTTCGGTGAGCTGCGTCCCGGTCACATCGTGGTCGTC
GGCACCGAGGGCGAAGGGGACGAGAAGAAGTTCTCGTTCCGCGGCGAGGAGAAGTCCGCTCTGCCGGACGTCCCGCCGAT
CGAGCAGGCAGCGGGCGGCGGCCCGAACCTGACGAAGGAAGCGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYSGGKEAATAGGPAEG
TPSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLK
DKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGAT
TLDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLI
DEAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGEL
IAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELS
KTLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILE
DGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDVKTNYERMKVKVNEELKQHFRPEFLNRVDDTVVFHQL
TEEDIIQIVDLMVAKVDERLKDRDMGIELSAEAKSLLAKKGYDPVMGARPLRRTIQREIEDILSEKILFGELRPGHIVVV
GTEGEGDEKKFSFRGEEKSALPDVPPIEQAAGGGPNLTKEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_3495 YP_004924432.1 ATPase AAA VFG0079 Protein 0.0 62
Sfla_3495 YP_004924432.1 ATPase AAA VFG0080 Protein 1e-149 53