Gene Information

Name : Sfla_2443 (Sfla_2443)
Accession : YP_004923389.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Unknown
Product : GMP synthase large subunit
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2906273 - 2907859 bp
Length : 1587 bp
Strand : -
Note : KEGG: sgr:SGR_2745 GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I

DNA sequence :
GTGCCAGCAGCACCCCCCGCCGCCCCCGACACCACGACCGACGTCGTCCTGGTAGTCGACTTCGGCGCCCAGTACGCCCA
GCTCATCGCCCGCCGTGTCCGTGAGGCCCGGGTCTACAGCGAGATCGTCCCGTCCACCATGCCGGTGGCCGAGATGCTGG
CCAGGAACCCCCGGGCGATCATCCTCTCCGGCGGCCCGTCCTCGGTGTACGCGGAGGGCGCGCCCAGCATCGACCGTTCG
CTGTTCGAAGCCGGGGTCCCGGTCTTCGGCATGTGCTACGGCTTCCAGCTCATGGCCACCACGCTCGGCGGCACGGTCGA
CGACAACGGTGCGCGCGAGTACGGTCGCACCCCCCTCGCCGTCTCCAAGGCGGGCTCCACCCTCTTCGAGGGCACGCCCA
CCGAGCAGCCGGTCTGGATGTCGCACGGCGACGCCTGCTCCGCCGCCCCCGAGGGCTTCACCGTGACCGCGTCCACGGAC
GTCGTCCCGGTCGCCGCCTTCGAGAACGACGAGAAGAAGCTCTACGGCGTCCAGTACCACCCGGAGGTCATGCACTCGAC
CTACGGCCAGCAGGTCCTGGAGCACTTCCTCTACCGCGGCGCGGGCATCGAGCCGACCTGGACGACCACCAACGTCGTCG
ACGAGCAGATCGCCCTGATCCGCGAGCAGGTCGGCGACAAGCGCGCGATCTGCGGCCTCTCCGGCGGCGTGGACTCCGCG
GTCGCCGCGGCCCTCGTGCAGAAGGCCATCGGCTCCCAGCTCACCTGCGTGTACGTCGACCACGGCCTGATGCGCAAGGG
CGAGACGGAGCAGGTCGAGAAGGACTTCGTCGCCGCGACCGGCGCGAAGCTCAAGGTCGTCGACGCGGAGAAGCGCTTCC
TCGACGCCCTGGCCGGCGTGTCCGACCCGGAGCAGAAGCGGAAGATCATCGGCCGCGAGTTCATCCGTGTCTTCGAGCAG
GCCCAGCTGGAGATCCTCCAGGAGGAGGGCCCCGAAGTCGCCTTCCTCGTCCAGGGCACCCTGTACCCGGACGTCGTCGA
GTCCGGCGGCGGCACCGGCACCGCCAACATCAAGTCCCACCACAACGTGGGCGGGCTCCCCGACGACATCGAGTTCGAAC
TCGTCGAGCCGCTGCGCCAGCTGTTCAAGGACGAGGTCCGGATGGTCGGCCAGGAGCTCGGCCTGCCCGAGGAGATCGTC
CAGCGGCAGCCGTTCCCCGGCCCCGGGCTCGGGATCCGCATCGTGGGCGACGTCACCAAGGAGCGGCTCGACCTGCTGCG
CGAGGCCGACGCCATCGCCCGCGAGGAGCTGACCGCCGCCGGCCTCGACCGTGACATCTGGCAGTGCCCCGTGGTCCTGC
TCGCGGACGTCCGCAGCGTCGGCGTCCAGGGCGACGGCCGCACCTACGGCCACCCGATCGTGCTGCGCCCGGTCTCCTCC
GAGGACGCCATGACGGCCGACTGGTCGCGCCTGCCGTACGAGACGCTGGCGAAGATCTCCACCCGCATCACCAACGAGGT
CGCCGACGTCAACCGCGTGGTGCTCGACGTGACGAGCAAGCCGCCGGGGACGATCGAGTGGGAGTGA

Protein sequence :
MPAAPPAAPDTTTDVVLVVDFGAQYAQLIARRVREARVYSEIVPSTMPVAEMLARNPRAIILSGGPSSVYAEGAPSIDRS
LFEAGVPVFGMCYGFQLMATTLGGTVDDNGAREYGRTPLAVSKAGSTLFEGTPTEQPVWMSHGDACSAAPEGFTVTASTD
VVPVAAFENDEKKLYGVQYHPEVMHSTYGQQVLEHFLYRGAGIEPTWTTTNVVDEQIALIREQVGDKRAICGLSGGVDSA
VAAALVQKAIGSQLTCVYVDHGLMRKGETEQVEKDFVAATGAKLKVVDAEKRFLDALAGVSDPEQKRKIIGREFIRVFEQ
AQLEILQEEGPEVAFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPDDIEFELVEPLRQLFKDEVRMVGQELGLPEEIV
QRQPFPGPGLGIRIVGDVTKERLDLLREADAIAREELTAAGLDRDIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSS
EDAMTADWSRLPYETLAKISTRITNEVADVNRVVLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-179 73
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-135 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-135 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-135 52