Gene Information

Name : Sfla_2345 (Sfla_2345)
Accession : YP_004923291.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2799703 - 2801166 bp
Length : 1464 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: sgr:SGR_2630 aldehyde dehydrogenase

DNA sequence :
ATGGCATCTGCTTTCGAATACGCACCGGCTCCGGAGTCCCGCTCCGTCGTCGACATCGCCCCCTCGTACGGCCTCTTCAT
CGACGGCGAGTTCGCCGAGGCGGCCGACGGCAAGGTCTTCAAGACGGTCAGCCCCTCCACCGAGGAGGTGCTGTCCGAGG
TCGCGCAGGCCGGCACCGAGGACGTGGACCGGGCCGTGAAGGCCGCGCGCAGGGCCTTCGAGAAGTGGTCGGCGCTGCCC
GGCTCCGAGCGCGCCAAGTACCTGTTCCGGATCGCCAGGATCATCCAGGAGCGTTCGCGCGAGCTGGCCGTCCTGGAGAC
GCTGGACAACGGGAAACCGATCCGGGAGACCCGCGACGCGGACCTCCCGCTGGTCGCCGCGCACTTCTTCTACTACGCGG
GCTGGGCCGACAAGCTCGACCACGCGGGGTTCGGCCGGAGGACGACAGAGGGAATCGCCGGCGCGACCCCCCGCCCGCTC
GGGGTGGCCGGTCAGATCATCCCGTGGAACTTCCCGCTGCTGATGCTGGCCTGGAAGATCGCCCCGGCGCTCGCCACGGG
CAACACCGTGGTGCTGAAGCCCGCGGAGACGACACCGCTGTCCGCGCTGTTCTTCGCCGACATCTGCCGGCAGGCAGGCC
TGCCCAAGGGCGTCGTCAACATCCTCACGGGGTACGGCGACGCGGGCGAGGCTCTCGTCGCGCACCCCGACGTGAACAAG
GTCGCCTTCACCGGCTCGACCGCCGTGGGCAAGGCCATCGCCCGGCAGATCGCCGGCACCGGCAAGAAGGCCACGCTCGA
ACTGGGCGGCAAGGGCGCGAACATCGTCTTCGACGACGCGCCTGTCGACCAGGCCGTCGAGGGCATCGTCACGGGGATCT
TCTTCAACCAGGGCCAGGTCTGCTGTGCGGGCTCGCGGCTCCTCGTGCAGGAGTCCGTGCACGACGAGGTGCTGCACGCC
CTCAAGCGCAGGCTGTCCACGCTCCGGCTCGGCGATCCGCTGGACAAGAACACCGACATCGGCGCGATCAACTCCGCGGA
GCAGCTCGCCCGGATCGGCGCGCTCGTGGAGACCGGTGAGGCCGAGGGCGCGGAGCGGTGGTCCGCGCCGTGCGAACTTC
CCTCCGCCGGTTACTGGTTCGCCCCGACCCTCTTCACCGGGGTCAGCCAGGCGCACACCGTCGCCCGCGACGAGATCTTC
GGCCCGGTGCTGTCGGTGCTGACGTTCCGCACGCCGGACGAAGCCGTCGCCAAGGCCAACAACACCCAGTACGGCCTCTC
CGCGGGCATCTGGACGGAGAAGGGCTCCCGCATCCTCGCGGTGGCGAACAAGCTCCGCGCCGGCGTCGTGTGGGCCAACA
CGTTCAACAAGTTCGACCCGACCTCGCCGTTCGGCGGATACAAGGAGTCGGGCTTCGGCCGCGAGGGCGGCCGTCACGGT
CTGGAGGCCTACCTCGATGTCTGA

Protein sequence :
MASAFEYAPAPESRSVVDIAPSYGLFIDGEFAEAADGKVFKTVSPSTEEVLSEVAQAGTEDVDRAVKAARRAFEKWSALP
GSERAKYLFRIARIIQERSRELAVLETLDNGKPIRETRDADLPLVAAHFFYYAGWADKLDHAGFGRRTTEGIAGATPRPL
GVAGQIIPWNFPLLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNILTGYGDAGEALVAHPDVNK
VAFTGSTAVGKAIARQIAGTGKKATLELGGKGANIVFDDAPVDQAVEGIVTGIFFNQGQVCCAGSRLLVQESVHDEVLHA
LKRRLSTLRLGDPLDKNTDIGAINSAEQLARIGALVETGEAEGAERWSAPCELPSAGYWFAPTLFTGVSQAHTVARDEIF
GPVLSVLTFRTPDEAVAKANNTQYGLSAGIWTEKGSRILAVANKLRAGVVWANTFNKFDPTSPFGGYKESGFGREGGRHG
LEAYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-74 43
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-71 43
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 9e-53 42
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 1e-53 42
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 1e-53 42
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 1e-53 42
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 9e-53 42
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 8e-54 42
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 3e-53 42
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 3e-53 42
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 1e-53 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-77 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-77 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-77 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_2345 YP_004923291.1 aldehyde dehydrogenase VFG0082 Protein 2e-74 43