Gene Information

Name : Sfla_2311 (Sfla_2311)
Accession : YP_004923257.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 2766275 - 2767420 bp
Length : 1146 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sgr:SGR_2579 cystathionine gamma-synthase

DNA sequence :
ATGAGCGACCAGCACAGCTTCGAGACCCTTGCGATCCATGCCGGCAACACGGCGGATCCCCTCACCGGCGCAGTGGTCCC
GCCGATCTACCAGGTGTCCACGTACAAGCAGGACGGTGTCGGCGGGCTGCGCGGCGGCTACGAGTACAGCCGCAGCGCCA
ACCCCACCCGCACGGCGCTGGAGGAGAACCTCGCCGCGCTGGAGGGCGGCCGCCGCGGGCTCGCCTTCGCGTCCGGCCTC
GCCGCGGAGGACTGCCTCCTGCGTACGCTGCTCACCCCCGGTGACCACGTGGTCATCCCGAACGACGCCTACGGCGGCAC
GTTCCGGCTGTTCGCGAAGGTCGCCTCGCGCTGGGGCGTGGAGTTCTCGGTCGCCGACACCTCCGACGTGAGCGCGGTCC
GCGCCGCGCTCACCCCGCGCACCAGGGCGATCTGGGTGGAGACGCCGTCCAACCCGCTGCTCGGCATCACCGACATCGCC
GCCGTCGCGGGTGTGGCCCGGCAGGCGGGCGCGCGGCTGGTGGTCGACAACACCTTCGCCAGCCCCTACCTGCAGCAGCC
GCTCTCGCTCGGTGCCGACGTCGTCGTGCACTCCACCACGAAGTACATGGGCGGGCACTCCGACGTCGTCGGCGGCGCGC
TCGTCGTCAACGACCCGGAGCTGGCCGAGGAGCTGGCGTACCACCAGAACGCCATGGGCGCGGTGGCCGGGCCGTTCGAC
GCGTGGCTGGTCCTGCGCGGCATCAAGACCCTCGCGGTCCGCATGGACCGCCACGACGAGAACGCGACGAAGGTCGCCGA
CCTGCTGACCCGTCACCCCAAGGTCACGCAGGTCCTCTACCCGGGGCTGCCGGAGCACCCGGGGCACGAGATCGCCGCCA
AGCAGATGAAGGCGTTCGGCGGGATGGTGTCGTTCCGGGTCTCGGGCGGCGAGGAAGCGGCCGTCGAGGTCTGCAACCGC
GCCGAGCTGTTCACGCTCGGGGAGTCGCTCGGCGGCGTCGAGTCGCTCCTTGAGCACCCGGGCCGCATGACGCACGCGTC
CGCGGCGGGCTCTCCGCTGGAGGTGCCGGCCGACCTGGTCCGGCTGTCCGTCGGCATCGAGAACGCCGACGACCTGCTGG
CCGACCTGACGCAGGCGCTCGGCTGA

Protein sequence :
MSDQHSFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFASGL
AAEDCLLRTLLTPGDHVVIPNDAYGGTFRLFAKVASRWGVEFSVADTSDVSAVRAALTPRTRAIWVETPSNPLLGITDIA
AVAGVARQAGARLVVDNTFASPYLQQPLSLGADVVVHSTTKYMGGHSDVVGGALVVNDPELAEELAYHQNAMGAVAGPFD
AWLVLRGIKTLAVRMDRHDENATKVADLLTRHPKVTQVLYPGLPEHPGHEIAAKQMKAFGGMVSFRVSGGEEAAVEVCNR
AELFTLGESLGGVESLLEHPGRMTHASAAGSPLEVPADLVRLSVGIENADDLLADLTQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-67 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-68 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-52 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_2311 YP_004923257.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 3e-55 45