Gene Information

Name : Sfla_0196 (Sfla_0196)
Accession : YP_004921181.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Resistance
Product : Beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2367
EC number : -
Position : 246565 - 247575 bp
Length : 1011 bp
Strand : +
Note : KEGG: sgr:SGR_457 beta-lactamase; PFAM: beta-lactamase

DNA sequence :
GTGCTGCGGGTGGACCGGCTGTCGCCGCGCGCCGTCCCACGGAGCAAGGAAGCCACCGCCACCGTGCCCACGCCTCTCCC
CCGCCGTACCGCGCTCCGCACCCTCGCCGGCCTCGTCGCCCTCCCTGTCGCCGCTTGCGACCCGACCACTCCGGCTGCCG
CGCCTCCCGCCGTCCCCTCGACGCCCGGAGGGTCAGGACACCGTCCGGGGCGCGCGTTCCAGGGGCTGGAGAAGAGGTTC
GGGGCCAGGCTGGGGGTGTACGCGATCGACACCGGGACCGGCGCGTCCGTCACCCACCGCCCCGACGAACGCTTCGCCTA
CGCCTCCACCTGCAAGGCCCTGCTGGCGGGCACTGTGCTGGGCATGCACACGCTTCAGCAGCTCGAACGGCGCGTGCGGT
ACGGGCCCGGCGACCTCGTCGCCAACTCCCCGGTGTCCGAGCGGCACGTCGAGGCGGGCATGACCCTGCGCGCCCTGTGC
GACGCCGCCGTCCGCCACAGCGACAACACCGCGGCGAATCTCCTCTTCCGCGAGATCGGGGGGCCCCGTCGCCTCCAGGA
CGCGCTCCTCGCCCTCGGTGACCGGACCACCCGCTGCGACCGCTACGAGACCGATCTCAGTGAGGCGGCACCCGGTGACC
CCCGGGACACCAGCACGCCTCGGGCCCTGGCCACCGATCTGCGCGCGTACGCGCTCGGCGACGTCCTCGGCGATGAGAAG
CGGGCCGTACTGACCGACTGGCTCAGGCGGAACACCACGGGAGACGCCCTCATCCGCGCGGGAACCCCCGCCGGCTGGCC
CGTGGGCGACAAGACCGGTACGGGCGGCTACGGAACCCGCAACGACATCGCGGTCGTGTGGCCACCTCACTCCGCGCCGA
TCACGATCGCCGTACTGTCCCGTCGGGCCAGCCGCGGAGCGAAGCCGCAGGACGCGCTGATCGCCCGGGCGGCCCGTGTC
GCGCTCACGGCTCTCGCCGGACAGAAGTATCCCGTCCCTCAGGGGCGGTAG

Protein sequence :
MLRVDRLSPRAVPRSKEATATVPTPLPRRTALRTLAGLVALPVAACDPTTPAAAPPAVPSTPGGSGHRPGRAFQGLEKRF
GARLGVYAIDTGTGASVTHRPDERFAYASTCKALLAGTVLGMHTLQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALC
DAAVRHSDNTAANLLFREIGGPRRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEK
RAVLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRRASRGAKPQDALIARAARV
ALTALAGQKYPVPQGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaCTX-M2 ACF06162.1 beta-lactamase CTX-M2 Not tested Tn5036-like Protein 8e-42 46
blaTEM-1b ACK44542.1 BlaTEM-1b beta lactamase Not tested SGI1 Protein 1e-38 44
blaTEM-1b ACF06168.1 beta-lactamase TEM-1b Not tested Tn5036-like Protein 1e-38 44
blaTEM-1 ADI24150.1 beta-lactamase TEM-1 Not tested AbaR1 Protein 1e-38 44
blaTEM-1b AGK07035.1 TEM-1b beta lactamase Not tested SGI1 Protein 1e-38 44
blaTEM-1b AGK07093.1 TEM-1b beta lactamase Not tested SGI1 Protein 1e-38 44
blaTEM AFV53104.1 TEM-1 beta-lactamase Not tested AbGRI2-1 Protein 1e-38 44
ABTW07_3874 YP_005797122.1 beta-lactamase TEM Not tested AbaR4e Protein 1e-38 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_0196 YP_004921181.1 Beta-lactamase AF367983.gene.p01 Protein 5e-69 57
Sfla_0196 YP_004921181.1 Beta-lactamase EU729727.1.gene1.p1 Protein 2e-48 50
Sfla_0196 YP_004921181.1 Beta-lactamase FJ234412.1.gene1.p01 Protein 9e-49 50
Sfla_0196 YP_004921181.1 Beta-lactamase GQ140348.1.gene1.p01 Protein 1e-47 50
Sfla_0196 YP_004921181.1 Beta-lactamase AF395881.gene.p01 Protein 4e-48 50
Sfla_0196 YP_004921181.1 Beta-lactamase HQ641421.1.gene1.p01 Protein 4e-48 49
Sfla_0196 YP_004921181.1 Beta-lactamase EU555534.1.gene1.p01 Protein 5e-49 49
Sfla_0196 YP_004921181.1 Beta-lactamase AF297554.1.gene1.p1 Protein 5e-48 49
Sfla_0196 YP_004921181.1 Beta-lactamase HM066995.1.gene1.p01 Protein 4e-48 49
Sfla_0196 YP_004921181.1 Beta-lactamase AY034847.1.gene1.p01 Protein 2e-48 49
Sfla_0196 YP_004921181.1 Beta-lactamase AY303807.gene.p01 Protein 2e-42 47
Sfla_0196 YP_004921181.1 Beta-lactamase GQ149243.1.gene1.p01 Protein 2e-42 47
Sfla_0196 YP_004921181.1 Beta-lactamase DQ102702.1.gene1.p1 Protein 2e-42 47
Sfla_0196 YP_004921181.1 Beta-lactamase FJ873739.1.gene1.p01 Protein 3e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase DQ408762.1.gene1.p1 Protein 6e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase EF374097.1.gene1.p01 Protein 6e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase X92507.1.gene1.p01 Protein 5e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase HM776707.1.gene1.p1 Protein 5e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase AJ567481.1.gene1.p01 Protein 7e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase GU127598.1.gene1.p1 Protein 6e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase DQ125241.gene.p01 Protein 5e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase GQ149244.1.gene1.p01 Protein 5e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase AJ416344.1.gene1.p01 Protein 7e-42 46
Sfla_0196 YP_004921181.1 Beta-lactamase Y14156.1.gene1.p01 Protein 2e-41 45
Sfla_0196 YP_004921181.1 Beta-lactamase AJ005045.gene.p01 Protein 5e-41 45
Sfla_0196 YP_004921181.1 Beta-lactamase AY327540.1.gene1.p01 Protein 5e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase EF136376.1.gene1.p01 Protein 3e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF427127.1.gene1.p01 Protein 7e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase FJ405211.1.gene1.p01 Protein 2e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase Y17581.1.gene1.p01 Protein 8e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase NC_011586.7045197.p0 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase HQ529916.1.gene1.p01 Protein 4e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF397068.1.gene1.p1 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY589494.1.gene1.p01 Protein 7e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF516719.1.gene1.p1 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase Y14574.2.gene1.p01 Protein 9e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase FJ873740.1.gene1.p01 Protein 3e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase FN652295.1.gene1.p01 Protein 1e-35 44
Sfla_0196 YP_004921181.1 Beta-lactamase AM183304.1.gene1.p01 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY101578.1.gene1.p01 Protein 4e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY072920.1.gene1.p1 Protein 5e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase GU371926.1.gene94.p0 Protein 8e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AJ318093.1.gene1.p01 Protein 1e-35 44
Sfla_0196 YP_004921181.1 Beta-lactamase HQ451074.1.gene4.p01 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AJ634602.gene.p01 Protein 3e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF397067.1.gene1.p1 Protein 5e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF347054.1.gene1.p1 Protein 8e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF190693.1.gene1.p01 Protein 1e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase DQ286729.1.gene1.p1 Protein 2e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AJ318094.1.gene1.p01 Protein 9e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase NC_010558.1.6276043. Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY368236.1.gene1.p1 Protein 9e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase JN416112.1.gene1.p01 Protein 3e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase DQ909059.1.gene1.p1 Protein 7e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase EU274580.1.gene1.p1 Protein 1e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF157553.1.gene1.p1 Protein 7e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY956335.1.gene1.p1 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AM941159.1.gene1.p01 Protein 9e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AJ866988.1.gene1.p01 Protein 2e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase X65253.1.gene1.p01 Protein 3e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF516720.1.gene1.p1 Protein 4e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY589495.1.gene1.p01 Protein 2e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase U50278.1.gene2.p01 Protein 2e-41 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF351241.1.gene1.p01 Protein 5e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AJ277415.1.gene1.p01 Protein 3e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase X54606.1.gene1.p01 Protein 3e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase U95363.2.gene1.p01 Protein 1e-35 44
Sfla_0196 YP_004921181.1 Beta-lactamase AF427130.1.gene1.p01 Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY628199.1.gene1.p01 Protein 4e-36 44
Sfla_0196 YP_004921181.1 Beta-lactamase FJ919776.1.gene1.p01 Protein 5e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase JN254627.1.gene1.p01 Protein 1e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase EF136377.1.gene1.p01 Protein 2e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase Y13612.1.gene1.p01 Protein 1e-35 44
Sfla_0196 YP_004921181.1 Beta-lactamase FQ312006.1.gene118.p Protein 6e-39 44
Sfla_0196 YP_004921181.1 Beta-lactamase GU550123.1.gene1.p1 Protein 1e-38 44
Sfla_0196 YP_004921181.1 Beta-lactamase AY130284.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY130285.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF275256.gene.p01 Protein 1e-42 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY039040.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY307100.1.gene1.p1 Protein 4e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY327539.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase EU815939.1.gene1.p1 Protein 4e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase HM246246.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF427128.1.gene1.p01 Protein 3e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF427129.1.gene1.p01 Protein 4e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF495873.1.gene1.p1 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase Y17583.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF397066.1.gene1.p1 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AJ277414.1.gene1.p01 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase JN227084.1.gene1.p01 Protein 9e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF535127.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase Y10280.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF104442.1.gene1.p01 Protein 5e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY271267.1.gene1.p01 Protein 1e-37 43
Sfla_0196 YP_004921181.1 Beta-lactamase X65254.1.gene1.p01 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ679961.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF190695.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase Y17584.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY491682.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF091113.2.gene1.p01 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF506748.1.gene1.p1 Protein 9e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ834729.1.gene1.p1 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AJ239002.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF203816.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY574271.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ105528.2.gene1.p01 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase JN211012.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase EF468463.1.gene1.p01 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AM286274.1.gene1.p01 Protein 7e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ072853.1.gene1.p01 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ105529.2.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AJ746225.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase Y10281.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ834728.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ279850.1.gene1.p1 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY826417.1.gene1.p01 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY092401.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase Y17582.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase FJ197316.1.gene1.p1 Protein 6e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AM049399.1.gene1.p01 Protein 1e-37 43
Sfla_0196 YP_004921181.1 Beta-lactamase AJ308558.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase U37195.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase EF534736.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AM849805.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY853593.1.gene1.p1 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY628176.1.gene1.p01 Protein 1e-37 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY368237.1.gene1.p1 Protein 6e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase X64523.1.gene1.p01 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY589493.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase FJ807656.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY874537.1.gene1.p01 Protein 8e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY243512.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF468003.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF093512.1.gene1.p01 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase DQ075245.1.gene1.p01 Protein 7e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AM087454.1.gene1.p01 Protein 1e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase X57972.1.gene1.p1 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase FJ360884.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF190694.1.gene1.p01 Protein 8e-39 43
Sfla_0196 YP_004921181.1 Beta-lactamase Y10279.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF104441.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY528425.1.gene1.p1 Protein 4e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF190692.1.gene1.p01 Protein 6e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AF188199.1.gene1.p01 Protein 2e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase AY628175.1.gene1.p01 Protein 3e-38 43
Sfla_0196 YP_004921181.1 Beta-lactamase Z28968.gene.p01 Protein 5e-41 42