Gene Information

Name : Sfla_1908 (Sfla_1908)
Accession : YP_004922859.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2328826 - 2330253 bp
Length : 1428 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; KEGG: sgr:SGR_2113 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGCGCCGTTCCAAAATCGTCTGCACCCTCGGTCCCGCCGTCGACTCCCATGAGCAGCTCGTCGCTCTGATCGAGGCCGG
CATGAGCGTGGCCCGCTTCAACTTCAGTCACGGCACCCACGAGGAGCACCAAGGCCGTTACGACCGCGTCCGCAAGGCCG
CCGCCGAGACCGGCCGCGCCGTCGGCGTGCTCGCCGACCTCCAGGGCCCGAAGATCCGTCTCGGGAAGTTCGCCGAGGGT
CCGGTCGAACTGGTCCGCGGGGACGAGTTCGTCATCACCTCCGAGGACGTCCCGGGCGACAAGTCGGTCTGCGGCACCAC
CTACAAGGGGCTGCCCGGCGACGTCGTCAAGGGTGACCCGATCCTCATCAACGACGGCAACGTCGAGCTGAAGGTCGTCT
CGGTCGACGGCCCGCGGGTCACCACCATCGTCATCGAGGGCGGTGTCATCTCCGACCACAAGGGGATCAACCTCCCGGGT
GCGGCGGTCAACGTCCCGGCGCTGTCCGAGAAGGACGTCGAGGACCTGCGCTTCGCCCTGCGGATGGGCTGCGACCTGGT
CGCGCTGTCCTTCGTGCGGGACGCCGAGGACGTCAAGGACGTGCACAAGGTGATGGACGAGGAGGGCCGCCGGGTCCCCG
TCATCGCCAAGGTCGAGAAGCCGCAGGCCGTCGAGCACATGGAGGGCGTCGTCGCCGCCTTCGACGGTGTGATGGTGGCC
CGTGGTGACCTCGCCGTCGAGTATCCGCTCGAGAAGGTCCCGATGGTGCAGAAGCGCCTCATCGAGCTGTGCCGCCGCAA
CGCGAAGCCGGTGATCGTGGCGACCCAGATGATGGAGTCGATGATCACCAACTCGCGCCCGACCCGCGCCGAGGCGTCCG
ACGTCGCCAACGCGATCCTGGACGGCGCGGACGCGGTCATGCTGTCGGCGGAGTCCTCGGTCGGCGCGTACCCGATCGAG
ACGGTCAAGACGATGTCGAAGATCGTCGTCGCCGCCGAGGAGGAGCTCCTGTCCAAGGGCCTCCAGCCGCTGGTGCCGGG
CAAGAAGCCGCGCACCCAGGGTGGTTCGGTGGCCCGCGCGGCCTGCGAGATCGCGGACTTCCTGGACGGCAAGGCCCTCG
TCGCCTTCACCAAGTCCGGTGACACCGCCCGCCGCCTCTCCCGCTACCGCACGGCACAGCCGATCCTGGCCTTCACCACG
GAGGAGTCCACCCGCAGCCAGCTCGCGCTGAGCTGGGGCGTCGAGTCCTACGTCGTGCCGCACGTGGACAACACGGACGC
CATGGTCGACCTGGTGGACGCCGAGCTGCTGAAGCTGAACCGCTACAGCGACGGCGACACGATGGTCATCACGGCCGGCT
CGCCCCCCGGCGTCCCCGGAACCACCAACATGGTCCGGGTGCACCACCTGAGCGGCGAGCGCGCCTGA

Protein sequence : 
MRRSKIVCTLGPAVDSHEQLVALIEAGMSVARFNFSHGTHEEHQGRYDRVRKAAAETGRAVGVLADLQGPKIRLGKFAEG
PVELVRGDEFVITSEDVPGDKSVCGTTYKGLPGDVVKGDPILINDGNVELKVVSVDGPRVTTIVIEGGVISDHKGINLPG
AAVNVPALSEKDVEDLRFALRMGCDLVALSFVRDAEDVKDVHKVMDEEGRRVPVIAKVEKPQAVEHMEGVVAAFDGVMVA
RGDLAVEYPLEKVPMVQKRLIELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIE
TVKTMSKIVVAAEEELLSKGLQPLVPGKKPRTQGGSVARAACEIADFLDGKALVAFTKSGDTARRLSRYRTAQPILAFTT
EESTRSQLALSWGVESYVVPHVDNTDAMVDLVDAELLKLNRYSDGDTMVITAGSPPGVPGTTNMVRVHHLSGERA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-69 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-77 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-77 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-77 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_1908 YP_004922859.1 pyruvate kinase VFG0479 Protein 9e-78 41