Gene Information

Name : thiC (MEALZ_0657)
Accession : YP_004915949.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 720052 - 721920 bp
Length : 1869 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 843272; Product type e : enzyme

DNA sequence :
GTGAGCGCAGTCCGCCAAGAAATTCCTTCGACTACTGTCAGTAGTGTCAAAATCGATCCTTATCCGGCATCGGAAAAAGT
CTATGTACAAGGCAGTCGGCCTGATATCAAAGTGCCGATGCGCAAGATTACGTTATCCGATACTCCCGTGCATTTCGGTG
CTGAAAAAAATACCCCCCTTTACGTTTACGATACTTCAGGTGTGTATACCGACCCTAATGTCACGGTCGATTTAAGAAAA
GGCCTGCCGGTGGTGCGTTCCTCTTGGATTGAGGAGCGTGGCGATACCGAGTTGTTGTCAGGCCCGACATCAAAATTCGG
TCATGAAAGATTGCATGACCCCGAAACAGCACATTTGCGTTTCGAGCTTATTCGTCAGCCAAGACGTGCCAAGGCCGGTG
CGAATGTTTCGCAAATGCACTATGCGAGAAAAGGCATCATAACGCCGGAGATGGAATACATCGCGATCCGCGAAAACCAA
AAAATGGAAGAAATGCGCGATCTATGGAAAGATCAGCATCCCGGGCAATCTTTCGGCGCATCGATTCCCGATGTGATTAC
GCCTGAATTCGTACGCGACGAAGTGGCGCGCGGACGGGCGATCATTCCAGCCAATATCAACCACCCCGAATTGGAGCCGA
TGATTATCGGACGCAACTTTTTGGTCAAGATCAACGGCAACCTCGGTAATTCGGCGGTGACTTCCTCCATAGAAGAAGAG
GTCGAAAAAATGCTTTGGGGCATTCGCTGGGGCGGCGACACGATCATGGACTTATCGACAGGTAAGAACATCCATGAGAC
CCGCGAATGGATATTGCGTAACTCGCCTGTGCCGATCGGAACCGTACCGATTTACCAGGCGCTGGAAAAAGTCGACGGCA
AGGCAGAGGAACTGACTTGGGAAATTTACCGCGACACGTTGATCGAGCAAGCCGAGCAGGGCGTCGATTATTTCACGATA
CATGCCGGCGTGCGGTTGCAGCATGTGCCGATGACCGCCAAACGTATGACCGGGATTGTGTCTCGCGGCGGTTCAATCAT
GGCCAAATGGTGCTTGGCGCATCATACCGAAAGCTTCCTCTATACCAACTTCGAGGAAATCTGCGAAATCATGAAAGCCT
ACGATGTTTCCTTTTCGTTAGGTGACGGTTTACGTCCCGGGTCGATTTACGATGCCAACGACGAAGCGCAGTTCGCCGAA
TTGGAAACTTTGGGCGAATTGACCAAGATCGCATGGAAGCATGACGTGCAGACGATGATCGAAGGACCGGGTCATGTGCC
GTTGCACATGGTCAAGATCAACATGGAAAAGCAGCTTGAAGACTGTCATGAAGCGCCATTCTATACTTTAGGTCCGCTAA
CGACCGATATCGCTCCTGGCTACGACCATATAACCTCGGCGATCGGTGCCGCGAACATTGGTTGGTACGGTTGCGCGATG
CTATGTTACGTTACGCAAAAAGAACATTTGGGTTTGCCTAACAAACAGGATGTCCGCGAAGGTATCGTGACTTACAAAAT
TGCCGCGCACGCCGCCGATTTAGCTAAGGGTCATCCGGGCGCTCAAGCACGCGACAATGCAATGTCGAAAGCCCGCTTCG
AATTCCGTTGGGAAGACCAATTCAACATCGGCCTCGATCCCGAGCGCGCACGCGAGTTTCATGACGAAACGCTGCCGAAA
CAATCGGCCAAGATTGCCCATTTCTGTTCGATGTGCGGACCGCATTTTTGTTCGATGAAAATCAGCCAGGATGTGCGCGA
CTACGCGGCTCAAAAAGGGGTGAAAGAAGAAGAAGCCCTGTTGATGGGAATGGAAGAAAAATCCAAGGAATTTCTTGAAG
AAGGCGCGGCCATCTATCACGAAGTTTAA

Protein sequence :
MSAVRQEIPSTTVSSVKIDPYPASEKVYVQGSRPDIKVPMRKITLSDTPVHFGAEKNTPLYVYDTSGVYTDPNVTVDLRK
GLPVVRSSWIEERGDTELLSGPTSKFGHERLHDPETAHLRFELIRQPRRAKAGANVSQMHYARKGIITPEMEYIAIRENQ
KMEEMRDLWKDQHPGQSFGASIPDVITPEFVRDEVARGRAIIPANINHPELEPMIIGRNFLVKINGNLGNSAVTSSIEEE
VEKMLWGIRWGGDTIMDLSTGKNIHETREWILRNSPVPIGTVPIYQALEKVDGKAEELTWEIYRDTLIEQAEQGVDYFTI
HAGVRLQHVPMTAKRMTGIVSRGGSIMAKWCLAHHTESFLYTNFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQFAE
LETLGELTKIAWKHDVQTMIEGPGHVPLHMVKINMEKQLEDCHEAPFYTLGPLTTDIAPGYDHITSAIGAANIGWYGCAM
LCYVTQKEHLGLPNKQDVREGIVTYKIAAHAADLAKGHPGAQARDNAMSKARFEFRWEDQFNIGLDPERAREFHDETLPK
QSAKIAHFCSMCGPHFCSMKISQDVRDYAAQKGVKEEEALLMGMEEKSKEFLEEGAAIYHEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 76
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 76
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74