Gene Information

Name : MEALZ_3679 (MEALZ_3679)
Accession : YP_004918918.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Virulence
Product : type III restriction enzyme, res subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 4245343 - 4248384 bp
Length : 3042 bp
Strand : +
Note : -

DNA sequence :
ATGGTCAGTCAAACCAATGAACAAGCCTTAGAAGCGGCGATTGAGCTGGCGTTAACCGGCACTTGTCTTGAAGCTAAGAA
AGGAGGTATAACCGATATGGTTGTGCCGCCTTATGCTGCGCCGCACTGCGGTTATGTTGCTGGAATACCGGCTGATTTCA
ATATGCAATACGCCATCGATGAACGTTTCTTCTGGCAGTTTCTGGAAAAAACTCAGGAACAAGAGCTGGCCAAGCTTCAG
AAAAACAACCCGGGCGATTGGCAACGTAAGCTGCTTGAACGTTATGACCGACTGATCAAAAAGCACGGTATCTTACATCT
ATTGAAAAAAGGCTTAAGTGTCGATGATGCGCATTTTAACCTGCTGTATCCCGCACCACTCGCCAGTAGCAGTGAGAAAG
TAACGCAGAATTTTGCAAATAACATTTTCAGCTGCACAAGACAGGTTCGGTACTCGCTTGCCAATCCGCTGCAAGAGATC
GATATGGTGCTGTTCATCAATGGCATTCCTCTGGTCACGCTTGAGCTAAAGAATGCTTGGACGGGGCAGACTGCGCGTTA
TCACGGCCTGAAACAATACCGTGAAGACCGAGATACAACACAGCCGTTACTGACGTTTGGACGTTGCTTGGTGCATATGG
CGGTGGATACGGATGAGGTTTACATGACCACCAAATTGGCTGGGGAAAGTACCTTCTTCTTACCTTTTAACAAAGGGCAT
AATCTGGGCCAGGGTAATCCTCCAAATCCGCAGGGTCATAAAACAGCTTATCTTTGGGAAGAGATCTTCACCAAAGACAG
TATTGTCAACATCATTCAGCACTTTGTTCGGCTAGATGGCGGCAGCAAAGATCCATTGCCAAAGCGAACGCTCTTCTTCC
CGCGTTACCATCAGTTGGATGTTGTTCGAAAGTTGGTCGATCATGCCTCGAACAACGGCGTCGGTCAGACTTATTTGATT
CAGCACTCTGCCGGTTCAGGTAAGTCAAACTCGATCACTTGGGCGGCTTATCAGTTGATTGAAACCTACCCTGCGTCGGA
AGCGGTATCCGGTGGCAAAGGTCTGGAGCAACCTTTGTTTGACTCGGTGATTGTTGTCACAGATCGGCGTTTATTGGATA
AGCAACTCAGAGACAACATTAAGGAATTCTCTGAGGTCAAAAATATCATCGCCCCGGCACATAAGTCATCCGAGCTGAAA
CAGGCATTAGAGAATGGCAAGAAGATCATCATCACGACCATTCAAAAATTCCCCTTTATTATTGACGGCATTAGCGATCT
GAGTGATAAACGCTTTGCCGTGATTATTGATGAAGCTCACAGCTCGCAGTCGGGTTCGGCGCACGATAGCATGAACCGAG
CCATGGGGCGCACAGATGTCGAAGAAGCGGAAGATGCGCAAGACAAAATTCTGCAAGCCATGAATTCACGCAAAATGCGT
GGCAATGCCTCTTATTTGGCGTTCACGGCAACCCCGAAAAACAGCACCTTAGAGAAGTTTGGCCAGAAGCAAGCAGACGG
CACATTCAAACCATTTCATCTGTATTCGATGAAGCAAGCGATTGAAGAAGGCTTTATTTTGGATGTGCTGGCCAACTACA
CCACCTACAAAAGCTACTATGAGATTGAAAAATCCATTGCCGAGAACCCTGAGTTTGACACAAAGAAGGCACAGAAAAAG
TTAAGGGCTTATGTTGAGCGAAGCCAGCACACCATCGATACCAAGGCCGAAATCATGCTTGAGCATTTCATTCCACAGGT
GGTGAATGCCAAAAAGCTTAAGGGCAAGGGCAAAGGGATGGTGGTGACTCAAAATATTGAGGCAGCGATCCGCTACTACA
AAGCCATTCGTCGTATTTTGGAAGCGCAAGGCAATTCGTTTAAGGTTCTAATCGCCTTTTCCGGCACCAAGGAAGTGGAC
GGTATTGAGTACACCGAAGCCGATATCAACGGCTTTGCAGAAACCGACACCAAAGACAAATTTGATACCGATGAGTATCG
CTTATTGGTGGTTGCCAATAAGTACCTGACCGGCTTTGACCAACCCAAGCTTTGCGCCATGTATGTCGATAAAAAACTCG
CCAGCGTTTTGTGCGTGCAAGCACTATCCCGCCTTAACCGTAGTGCGCCGAAGTGGGGTAAAAAAACGGAAGACTTGTTT
GTTTTGGATTTCTTTAACTCCGCTGAAGATATTCAGGCTGCATTTGATCCGTTCTATACGGCGACTTCGTTGTCTCAGGC
AACCGATATCAATGTTCTGCATGAGTTAAAGGATGCTCTGGACGAGGTAGGGGTATATGAGTGGTACGAGGTAGAGAATT
TTGTTGCGCGTTTTTTTAACAATGAAGACGCGCAAACGTTAAGTCCGATTATTGATACCGCAGCGGCCAGATTTGAGAGC
GAATTGGAACTGGCGCCTGAAGCTAAAATAGACTTCAAAATCAAGGCCAAGCAGTTTGTTAAGATATACGGCCAAATGGC
ATCGATCATGCCTTATGAGATGGTGGCATGGGAAAAGCTATTCTGGTTCCTGAAGTTCTTGATCCCTAAACTAAAAGTGG
CAGACCCTGATGCGGATGCCATCGATGAACTGCTGGAGTCAGTAGACTTGAGCTCATACGGTTTACAACGTGTGAAACTC
AACCATGTAATCAAGCTGAACGATCAAGAAACAGAGCTCGACCCGCAAAACCCTAATCCTCGCGGTGCGCATGGCGGCGA
GAAAGAGGCTGATCCGCTAGACGAAATCATCCGTACCTTTAATGAGCGCTGGTTCCAAGGGTGGAGTGTGACGCCTGAAG
AGCAAAGAATTCGTTTATTGAGTATGCGAGATGCACTGACTAAGCATCCGGATTTTAAAAGTAAGTATCTGGAAAGCGCC
GATCCCCACAACCAGCATTTGGCTTTTGAAAAAATGGTGAAGGAAATCATGTTACAAAAACGAAAGGATGATTTGGACTT
CTATAAGCTTTGGGCAAATGATGCCGCTTTTAAAGCTTCGCTTATGAACAGTATACAGCGTATGGTTGACGGGTATATAT
AA

Protein sequence :
MVSQTNEQALEAAIELALTGTCLEAKKGGITDMVVPPYAAPHCGYVAGIPADFNMQYAIDERFFWQFLEKTQEQELAKLQ
KNNPGDWQRKLLERYDRLIKKHGILHLLKKGLSVDDAHFNLLYPAPLASSSEKVTQNFANNIFSCTRQVRYSLANPLQEI
DMVLFINGIPLVTLELKNAWTGQTARYHGLKQYREDRDTTQPLLTFGRCLVHMAVDTDEVYMTTKLAGESTFFLPFNKGH
NLGQGNPPNPQGHKTAYLWEEIFTKDSIVNIIQHFVRLDGGSKDPLPKRTLFFPRYHQLDVVRKLVDHASNNGVGQTYLI
QHSAGSGKSNSITWAAYQLIETYPASEAVSGGKGLEQPLFDSVIVVTDRRLLDKQLRDNIKEFSEVKNIIAPAHKSSELK
QALENGKKIIITTIQKFPFIIDGISDLSDKRFAVIIDEAHSSQSGSAHDSMNRAMGRTDVEEAEDAQDKILQAMNSRKMR
GNASYLAFTATPKNSTLEKFGQKQADGTFKPFHLYSMKQAIEEGFILDVLANYTTYKSYYEIEKSIAENPEFDTKKAQKK
LRAYVERSQHTIDTKAEIMLEHFIPQVVNAKKLKGKGKGMVVTQNIEAAIRYYKAIRRILEAQGNSFKVLIAFSGTKEVD
GIEYTEADINGFAETDTKDKFDTDEYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSAPKWGKKTEDLF
VLDFFNSAEDIQAAFDPFYTATSLSQATDINVLHELKDALDEVGVYEWYEVENFVARFFNNEDAQTLSPIIDTAAARFES
ELELAPEAKIDFKIKAKQFVKIYGQMASIMPYEMVAWEKLFWFLKFLIPKLKVADPDADAIDELLESVDLSSYGLQRVKL
NHVIKLNDQETELDPQNPNPRGAHGGEKEADPLDEIIRTFNERWFQGWSVTPEEQRIRLLSMRDALTKHPDFKSKYLESA
DPHNQHLAFEKMVKEIMLQKRKDDLDFYKLWANDAAFKASLMNSIQRMVDGYI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1765 NP_231400.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 75
VC0395_A1363 YP_001217306.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 75
VPI2_0013c ACA01830.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MEALZ_3679 YP_004918918.1 type III restriction enzyme, res subunit VFG1098 Protein 0.0 75