Gene Information

Name : pilR (MEALZ_3293)
Accession : YP_004918541.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Virulence
Product : type 4 fimbriae expression regulatory protein
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 3813471 - 3814808 bp
Length : 1338 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1317379, 7911557, 8097014; Product type r : regulator

DNA sequence : 
ATGAAACACCCCTTGACTTTAGTCGTCGACGACGAGCCGGATATCCGAGAGCTGTTAAGCATTACGCTCAAACGCATGAA
CATCGACACCTTGTGCGCGGAAAATGTCGACTCGGCTCGGCAGTTGTTACAACAACATCCGTTCGATCTTTGCCTGACCG
ACATGAAGCTACCCGACGGCAACGGGCTCGAATTGGTCGAATACCTCCAAAGCACGGGCAGCACGATTCCGATTGCCGTA
ATTACCGCACACGGCAACATGGATACTGCGATCAAGGCAATGAAAGCCGGGGCCTTCGACTTTATCTCAAAACCGGTCGA
TTTACCGGTACTTCGGCAAATCGTCACGAAAGCCTTACAACTAGCCCCCGATGCCGATACCAAGGAAAGGCGCACACGAC
ATATTTTATTGGGCGAATCGGAGCCGATGCGCCAAGTCCGGTCTAAAATCGACAAGCTGGCACGTAGTCAGGCGCCTGTT
TATATCAGCGGCGAATCGGGGTCGGGTAAGGAATTGGTGGCGCGCTTGATTCATCAACAAAGCCCGCGTAGCGACAAGCC
TTTTGTTGCCGTAAACTGCGGCGCGATCCCGCCCGAACTTATGGAAAGCGAGTTTTTCGGACATAAAAAAGGCAGTTTCA
GCGGTGCAATTGCCGATAAAAAAGGTTTATTTCAAGCAGCCGAGGGCGGTACGCTATTTCTCGATGAAGTCGCCGATCTG
CCTCCTTCGCTGCAAGTCAAATTACTCCGCGCGATTCAGGAAAAAAAAGTACGCGCAGTCGGCGAACAACACGAAACACC
GGTCGATGTCCGCATCCTGAGCGCCACGCATAAAGATTTGAATCAATTGGTTCAGGAAGGGGTTTTTCGGCAAGATTTAT
ACTACCGGATCAATGTCATCGATCTCAATATTCCGCCGCTTCGCGAACGAGGCAATGATATCGCGCAACTAGCCGAACAT
ATTCTAGCCTCGTTAAATAGTAACAACGCTTTTCAAGTCCGGCTTTCGCAATCGGCGTTGACTGCATTGAAACATTATCA
TTTTCCGGGCAATGTTAGGGAGCTCGAGAATATTCTGGAGCGCGCCGTTGCGCTCAGCGACGGCAAAACGATCGATGCGG
ACGATTTAAATCTACCGATTAATCCGGAAATCGTCCCTGATGCGCCAGCGTTCGATCCGTCAAAAGCGTCGTTGGAAGAT
TATTTGGAAGATATCGAGCGAACCGCCATTACCATCGCACTCGAAAATAACCGATGGAATAAAACCGCAGCAGCAAAAGA
GCTGGGGTTATCGTTCCGATCATTGCGTTACCGGTTAAAAAAACTGGGCTTGGACTAG

Protein sequence : 
MKHPLTLVVDDEPDIRELLSITLKRMNIDTLCAENVDSARQLLQQHPFDLCLTDMKLPDGNGLELVEYLQSTGSTIPIAV
ITAHGNMDTAIKAMKAGAFDFISKPVDLPVLRQIVTKALQLAPDADTKERRTRHILLGESEPMRQVRSKIDKLARSQAPV
YISGESGSGKELVARLIHQQSPRSDKPFVAVNCGAIPPELMESEFFGHKKGSFSGAIADKKGLFQAAEGGTLFLDEVADL
PPSLQVKLLRAIQEKKVRAVGEQHETPVDVRILSATHKDLNQLVQEGVFRQDLYYRINVIDLNIPPLRERGNDIAQLAEH
ILASLNSNNAFQVRLSQSALTALKHYHFPGNVRELENILERAVALSDGKTIDADDLNLPINPEIVPDAPAFDPSKASLED
YLEDIERTAITIALENNRWNKTAAAKELGLSFRSLRYRLKKLGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 6e-107 51
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 6e-107 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_004918541.1 type 4 fimbriae expression regulatory protein BAC0467 Protein 2e-73 42
pilR YP_004918541.1 type 4 fimbriae expression regulatory protein BAC0089 Protein 3e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR YP_004918541.1 type 4 fimbriae expression regulatory protein VFG1214 Protein 5e-141 65