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Name : pykA (MEALZ_3080) Accession : YP_004918331.1 Strain : Methylomicrobium alcaliphilum 20Z Genome accession: NC_016112 Putative virulence/resistance : Virulence Product : pyruvate kinase II Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : - Position : 3581405 - 3582850 bp Length : 1446 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1732206, 8439398, 91072271, 91315755; Product type e : enzyme DNA sequence : ATGTTACGAAGAACCAAAATACTGGCCACTTTGGGCCCCGCAACGGATAAACCCGGGGTCCTGGAAAACTTGTTCAAAGC CGGCATCGACGTGGTTCGCATGAATTTCTCGCACGGCTCGGCGCAAGACCATATTGACCGAGCCAACAAAGTTCGCGAAT TAAGCCGCAAAACCGGACGCCGCGTCGGCATATTAGGCGACCTGCAAGGCCCTAAAATACGCATAGCGCGTTTCAAGGAA ACGAAAGTATGGCTTGATGAAGGCCAGGATTTCGCCTTGGACATCAACTTAGGGCCGAACGACGGCGATAATACCCAAGT CGGCATCACTTACGAACCGCTGGCTCGCGAAGTGCGCAACGGCAGTCGTTTACTGTTGGACGATGGACGAGTGGTATTAG ATGTAGTCGATACCGACGGCAAACGCGTCAATTGCAAAGTAGTCGTCGGCGGCGACCTGTCCAACAACAAAGGTATCAAT TTGATGGGTGGCGGGCTTTCCGCCGCTGCTTTGACCGAAAAAGACAAGGAAGACATCAAAACGATTGCGAAAATCGATTG CGATTATGTTGCGGTATCTTTTCCTAGATGCGCAGCGGACTTGAACGAAGCACGCGAATTGCTGCTGGCGGAAGGTTGCC ATGCCGGCATCGTCGCTAAGGTCGAGCGCGCAGAAGCGATGGATGCAATGGATGAAATTATCCTGGCATCCGATGCGGTA ATGGTCGCTCGTGGCGACTTGGGCGTTGAAATTGGCGACGCTAACCTTCCGGCCGCACAGAAACGACTCATCAGCCGTGC TCGCGAACTGAATCGCATAGCGATCACTGCGACGCAAATGATGGAATCAATGATCGAAAACCCGATTCCGACTCGCGCCG AAGTTTTCGACGTTGCGAATGCGGTCGTCGACGGCACCGATGCGATCATGCTATCGGCCGAAACCGCTTCCGGTAAATAT CCGGTCAAAGCGGTCGAAGCGATGGTACGGGTTTGCGAAGAGACCGAAAAACAGCCGAGCGTTCGAGTTTCGAAGCATCG TATGGATACGCAATTCCAGCGCATCGACGAAGCGATTGCGATGTCGGCGATGTATATGGCGAATCATACGACGATTCATG GCATAGCGGCATTGACCGAATCCGGATCGACACCATTATGGATGTCCAGAATCAGCTCGGCAATTCCTATCTTCGCATTT AGCAGTCAGGAAAAAACTTTAGGCAAGGTAACGCTTTATCGAGGCGTATTTCCGTTCTATTTCGACAAACACTTGAAAGA ACCGGATCATGCCGAAGTGAACCGTGAAATCGTCAAACAGCTAAGAAAACGCCACCAAGCGCAAAATGGGGATAAATTCA TCATCACCAAAGGCGATCTAACCGGCGTTCAGGGCGGAACCAACGCATTGAAAGTGATTACAGTGGGTGAAGGCTTAACG CCTTAA Protein sequence : MLRRTKILATLGPATDKPGVLENLFKAGIDVVRMNFSHGSAQDHIDRANKVRELSRKTGRRVGILGDLQGPKIRIARFKE TKVWLDEGQDFALDINLGPNDGDNTQVGITYEPLAREVRNGSRLLLDDGRVVLDVVDTDGKRVNCKVVVGGDLSNNKGIN LMGGGLSAAALTEKDKEDIKTIAKIDCDYVAVSFPRCAADLNEARELLLAEGCHAGIVAKVERAEAMDAMDEIILASDAV MVARGDLGVEIGDANLPAAQKRLISRARELNRIAITATQMMESMIENPIPTRAEVFDVANAVVDGTDAIMLSAETASGKY PVKAVEAMVRVCEETEKQPSVRVSKHRMDTQFQRIDEAIAMSAMYMANHTTIHGIAALTESGSTPLWMSRISSAIPIFAF SSQEKTLGKVTLYRGVFPFYFDKHLKEPDHAEVNREIVKQLRKRHQAQNGDKFIITKGDLTGVQGGTNALKVITVGEGLT P |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykA | NP_273151.1 | pyruvate kinase | Not tested | IHT-A | Protein | 2e-74 | 44 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-57 | 44 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-57 | 44 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 2e-57 | 44 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 1e-56 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pykA | YP_004918331.1 | pyruvate kinase II | VFG0479 | Protein | 8e-58 | 44 |
