Gene Information

Name : clpB (MEALZ_2998)
Accession : YP_004918249.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Virulence
Product : Chaperone protein ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3467281 - 3469860 bp
Length : 2580 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11061966, 11717522, 14978298, 15208691, 2066329, 2185473, 8376377; Product type f : factor

DNA sequence :
ATGAGAATGGATAAACTGACCAGCAAGTTTCAGATGGCGTTGGCCGATGCGCAAAGCCTGGCTTTGGGCAAGGATCATCA
ATTCATCGAGCCGGCCCATGTGATGCTGGCGTTATTAAATCAGGACGGCGGCAGTATTCGGCCGCTGTTGTCGCAAATCG
GCGCAAACCCGAATATCGTACAGGCCGAATTGACCAAGGTGCTTGAACGCACCCCAACCGTTTCAGGAATCGGCGGCGAC
GTGCAGATTTCCAACGAATTGTCGCGCTTGTTGAACGTGACCGACAAGCTCGCGCAAAAACGCGGCGACAAATTTATCTC
GAGCGAATTGTTTTTATTGGCCGCCTGCGAAACATCGGGCGCTCTGCAAGATATCCTAAAAAAAGCCGGCGTGACCCGAG
CGGCTGCGGAAAAAGCCATAGACAATGTCCGTGGCGGACAAAACATCGACGATGCCAACGCCGAGGAGCAACGTCAAGCA
TTAAGCAAATACACGATCAATCTGACCGAGCAAGCCGAACAGGGTAAGCTCGATCCGGTGATCGGCCGCGACGACGAAAT
CCGCCGCACGATACAAGTCTTGCAGCGCCGCACCAAAAACAACCCGGTATTGATCGGCGAGCCCGGCGTCGGCAAGACCG
CGATTGTCGAAGGTTTGGCGCAGCGCATCGTCAACGGTGAAGTTCCCGAAGGTATCAAAGGCAAACAATTGTTGTCCCTC
GATATGGCCGCGCTGATCGCCGGCGCGAAATTCCGCGGCGAATTCGAGGAGCGCCTGAAAGCAGTGTTGAACGATATCGC
GAAACAACAAGGCCAGGTTATTCTGTTCGTCGATGAATTGCATACGATGGTCGGTGCCGGTAAGGCGGAAGGCGCGATGG
ATGCTGGTAACATGCTCAAACCCGCTTTGGCGCGCGGCGAGCTGCATTGCGTCGGTGCGACCACCCTAGACGAATACCGT
AAATACATCGAAAAAGACGCGGCCTTGGAGCGCCGTTTCCAAAAAGTCTTGGTCGACGAGCCGAACGTCGAAGATACCAT
CGCGATCTTGCGCGGCTTGAAGGAGAAATACGAAGTGCATCATGGCGTCGATATCACCGATCCCGCGATCGTCGCGGCCG
CAACGCTCTCGCATCGTTACATTTCCGACCGGCAACTGCCCGACAAGGCGATCGATTTGGTCGATGAAGCGGCAAGCCGC
ATTCGCATGGAAATCGACTCGAAACCGGAGGCGATGGATAGGCTGGACCGGCGTTTGATTCAATTGAAGATCGAACGCGA
GGCATTGAAAAACGAAACCGATGAAGCGTCTAAAAAACGTTTGGAAAGCCTTGAGGAAGCGATCGAGAACCTGGAAAAAG
AATATTCCGAGTTCGACGAAATTTGGAAAGCCGAAAAAGCCGCGCTGCAAGGCACGACCGCGATCAAGGAAAGACTGGAA
CAAGCCCGTTTGGAATTGGAAGTTGCCAGTCGCGCGAACGATCTGAGCCGCATGTCGGAATTGCAATACGGCGTGATCCC
TTCGCTGGTCAAGGAATTGGATCTGGCGTCGCAGGCCGAAATGCAGGAAATGAAACTGCTTCGCAATAAGGTAACCGATG
AAGAAATCGCCGAAGTCGTCTCGAAATGGACCGGTATTCCGGTCTCGAAAATGATGGAAGGCGAGCGCGATAAATTATTG
CGCATGGAAGAGCAGATCCAAAAACGCGTGGTCGGACAAACCGAGGCGCTGATCTCGGTTAGCAACGCGATTCGCCGTTC
GCGCGCGGGTCTCTCCGACCCGAACCGGCCGAACGGTTCGTTCCTGTTCTTGGGGCCGACCGGCGTCGGCAAAACCGAAC
TGTGCAAGGCATTGGCCGAATTCTTGTTCGATACCGAAGAAGCGATGGTGCGCATCGACATGTCCGAATTCATGGAGAAG
CATTCGGTCGCGCGTTTGATCGGCGCGCCTCCGGGCTATGTCGGCTACGAAGAAGGCGGTTATTTGACCGAAGCGGTGCG
GCGCAAGCCTTATTCGGTAATTTTGCTCGACGAGGTCGAAAAGGCGCATCCGGACGTGTTCAACGTGCTGCTGCAAGTGC
TCGACGACGGCCGGTTGACCGATGGGCAGGGCAGAACGGTCGATTTCCGCAATGCCGTCGTCGTGATGACGTCGAACCTC
GGTTCGGACCGAATACAGGAGTTGGCAGGCGAAGAAAACTATGCGGCAATGAAATCGGCGGTTATGGAGGTAGTCGGCTA
CCATTTCCGTCCGGAGTTCATCAACCGTATCGACGACGTCGTCGTGTTCCATCCGCTCGGCCGCGACCAAATCCGGTCGA
TTACCGATATTCAGATCCGTTATCTGCGCAAACGTTTGCTCGATCACGATATCGATCTTGAGTTGAGCGAGGCGGCGCTG
GATAAACTCGGTGAAGCCGGATTCGACCCGGTTTACGGCGCAAGACCGCTGAAACGCGCGATACAACATCAATTGGAAAA
CCCGCTGGCGCAAGAGATTCTTGGCGGAAAATTCGGTCCAGGCGACAAAATTGTTGTCGATGTCGAGGGCGGGACATTGG
CGTTTTCGAAAGCGGCTTGA

Protein sequence :
MRMDKLTSKFQMALADAQSLALGKDHQFIEPAHVMLALLNQDGGSIRPLLSQIGANPNIVQAELTKVLERTPTVSGIGGD
VQISNELSRLLNVTDKLAQKRGDKFISSELFLLAACETSGALQDILKKAGVTRAAAEKAIDNVRGGQNIDDANAEEQRQA
LSKYTINLTEQAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGIKGKQLLSL
DMAALIAGAKFRGEFEERLKAVLNDIAKQQGQVILFVDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
KYIEKDAALERRFQKVLVDEPNVEDTIAILRGLKEKYEVHHGVDITDPAIVAAATLSHRYISDRQLPDKAIDLVDEAASR
IRMEIDSKPEAMDRLDRRLIQLKIEREALKNETDEASKKRLESLEEAIENLEKEYSEFDEIWKAEKAALQGTTAIKERLE
QARLELEVASRANDLSRMSELQYGVIPSLVKELDLASQAEMQEMKLLRNKVTDEEIAEVVSKWTGIPVSKMMEGERDKLL
RMEEQIQKRVVGQTEALISVSNAIRRSRAGLSDPNRPNGSFLFLGPTGVGKTELCKALAEFLFDTEEAMVRIDMSEFMEK
HSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNAVVVMTSNL
GSDRIQELAGEENYAAMKSAVMEVVGYHFRPEFINRIDDVVVFHPLGRDQIRSITDIQIRYLRKRLLDHDIDLELSEAAL
DKLGEAGFDPVYGARPLKRAIQHQLENPLAQEILGGKFGPGDKIVVDVEGGTLAFSKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 9e-105 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-103 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-103 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_004918249.1 Chaperone protein ClpB VFG2076 Protein 4e-109 41