Gene Information

Name : dnaB (MEALZ_2437)
Accession : YP_004917705.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Unknown
Product : Replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 2790692 - 2792098 bp
Length : 1407 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10404597, 20069637, 89123330, 89123331, 93374896, 99389554, 99389555; Product type e : enzyme

DNA sequence :
TTGACCGAAATTATGTCTGAAGAATATGTATTCGACCGCGATTACGCAACCGAAGCTTTAAAAGTATCGCCGCATTCAAT
ACAAGCCGAGCAATCCGTACTCGGCGGTTTGATGCTGGATAACCAAACCTGGGATTCGATAGCCGATAAAGTTGTCGAAG
GCGATTTTTATCGCAAAGATCATCGAATGATTTTTCGGGCCATCGAAAAATTGGCAGAAAAACAAGATCCTTTCGACGTC
ATTACCTTATCCGAGGCACTGGCTTCCGCCGGACAATTGAATGAGGTCGGCGGTCTGGCCTATTTAGGTACCTTGGCAAA
GGATACCCCGAGTGCCGCGAATATCGTCGCTTATGCAACCATAGTTCGCGATAAGTCGGTTTTAAGGCAATTGATTCATG
TCGGAACCGATATATCCGACTCGGCTTTTAGTCCGGAAGGGCGCGATACATCGGAGTTGCTCGAAAATGCCGAGCGTCAA
GTATTTCAAATTGCTGAACAGCGCCAACGCGGGCAGGGCGGTTTCACGTCGATCAAGTCGTTGCTGGCGCAAGCGGTCGA
TAAGATCGAAATGCTTTACGAGCAGGAAGGCAATATCACCGGCGCCAGCACCGGATTCAATGATTTCGACGAAATGACCT
CGGGTCTACAGCCGTCCGATTTAATTATTGTTGCTGGTCGGCCGTCAATGGGCAAAACTACGATCGCGATGAACATGGCG
GAGAATGTCGCAATTAAAGGCGATAAGCCGGTTGCGGTGTTCAGTATGGAAATGCCCGGCGACTCGTTAGCGATGCGGAT
GATGTCCTCATTGGGGCGTATCGATCAACATAAGATCAGAACCGGTAAACTCGATGACGACGAATGGCCTCGTTTGACTT
CGGCGATTAATTTATTGGCTGAAACGAAATTGTTCATCGACGATACGCCGGCTTTGACGCCGACTGAAGTCCGCTCGAGA
GCGCGACGATTGATGCGCGAACATGGCCAGTTGGGTTTGATCGTATTGGATTATCTGCAATTGATGCAGTCGCCGGCCAG
CGGCGATAATCGGGTTCAACAGATTTCGGATATCTCGAGGGGCTTGAAAGCCTTGGCCAAGGAGCTGAACGTGCCGGTTA
TCGCGCTCTCGCAGCTGAACCGTAACCTTGAGCAGCGGCCCAACAAACGGCCGGTGATGTCCGATTTGCGTGAGTCGGGA
GGTATCGAACAGGATGCCGACGTGATCGTATTTGTTTATCGGGATGAGGTTTACAACCCGGATAGTCCGGAGAAAGGTGT
TGCTGAAATTATCATCGGTAAACAACGTAACGGTCCGATAGGCACGGTCAGGTTGACTTTCCTCGGACAATACACTCGGT
TTGAAAACTTTGCCGGAAATCCTTACGGCGGAGACGATTACGAATGA

Protein sequence :
MTEIMSEEYVFDRDYATEALKVSPHSIQAEQSVLGGLMLDNQTWDSIADKVVEGDFYRKDHRMIFRAIEKLAEKQDPFDV
ITLSEALASAGQLNEVGGLAYLGTLAKDTPSAANIVAYATIVRDKSVLRQLIHVGTDISDSAFSPEGRDTSELLENAERQ
VFQIAEQRQRGQGGFTSIKSLLAQAVDKIEMLYEQEGNITGASTGFNDFDEMTSGLQPSDLIIVAGRPSMGKTTIAMNMA
ENVAIKGDKPVAVFSMEMPGDSLAMRMMSSLGRIDQHKIRTGKLDDDEWPRLTSAINLLAETKLFIDDTPALTPTEVRSR
ARRLMREHGQLGLIVLDYLQLMQSPASGDNRVQQISDISRGLKALAKELNVPVIALSQLNRNLEQRPNKRPVMSDLRESG
GIEQDADVIVFVYRDEVYNPDSPEKGVAEIIIGKQRNGPIGTVRLTFLGQYTRFENFAGNPYGGDDYE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-111 51
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 4e-101 50
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 2e-102 50
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 6e-103 50
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 5e-101 49
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 3e-97 48
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 2e-96 48
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 2e-96 48
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 2e-76 43