Gene Information

Name : MEALZ_2163 (MEALZ_2163)
Accession : YP_004917441.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Virulence
Product : reverse transcriptase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG3344
EC number : -
Position : 2445982 - 2447232 bp
Length : 1251 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology

DNA sequence :
ATGAGCGAGGCAAAGCCATTTGTCATTTCGAAATGGCAAGTGATGCGTGCATTTGAATTGGTGAAAGCCAATGCGGGTGC
TGCAGGTGTTGATAGGCAATCGTTGGCAGATTTTGAAAGAAATCTGAAAGACAATCTTTACAAGTTATGGAATCGGCTGT
CGTCCGGCAGTTACTTCCCGCCGCCTGTCAAAGCGGTAGCCATACCGAAGAAAGCAGGTGGCGAACGGATTTTGGGTATA
CCCACCGTGAGTGATCGTATTGCTCAGATGGTCGTCAAACTGGAATTTGAACCCCAGGTTGAGCCGCACTTTTTGCCTGA
CTCGTATGGCTACAGGCCGAATAAGTCAGCACTCGATGCGGTGGGTGTCACGCGAGAACGTTGTTGGCGCTATGACTGGG
TACTTGAGTTTGATATTAAGGGATTATTCGACAATATACCGCATGATCTATTGCTTAAAGCGGTCTATAAGCATACCGAT
ACGGCTTGGGTGAGATTGTATATCGAGCGCTGGTTGACGGTGCCGATGCAGATGCCCAATGGGGAATTGAGTAGCCGGGG
AAAAGGCACGCCACAAGGTGGAGTTGTCAGTCCGGTGCTCAGTAATCTGTTTCTGCACTATGTCTTCGACAAATGGTTGC
AAAAGCACTACTCGGATACACCCTGGTGTCGTTATGCCGATGATGGTCTGGTGCACTGCCGGAGTGAGGCAGAAGCCAAA
CACATGCTGGAAGCACTGAAACAACGCTTTCAGTCCTGTGGGCTTGAACTTCATCCGGTGAAAACCAAGATTGTTTACTG
TAAAGATGGAAGTCGCAAAGGGCGCTATAAGCATACCTCCTTTGATTTTCTGGGGTATACGTTCAGACGGCGACTGTGTA
GGAATCGCAAAAGAAACAGTGTGTTTGTAAACTTTACGCCGGCGGTGAGTAAAGCGGCGCTGAAGTCAATGCGAGGAAAG
GTCAGAAAGTTACGAGTCAGAACGCGTACCGAGTTGAGCTTAGGGCAAATAGCACAATGGTTGAATCCCATCATTAGGGG
ATGGATAGGCTATTATGGTTGTTATACCCGATCTGCGTTATATGGTATGTGTCGTCACGTCAACATGACTCTGGTGAGGT
GGGTAAGACGAAAGTTCAAGCCGCTACGCCAGCATAAAATAAAGGCAATGCTGTTTCTGGAGAAGATTGCAGATCAACAT
CCAAACTTGTTTGCCCATTGGCGGGCGGGAATGATAGGTGCGTTTGCCTGA

Protein sequence :
MSEAKPFVISKWQVMRAFELVKANAGAAGVDRQSLADFERNLKDNLYKLWNRLSSGSYFPPPVKAVAIPKKAGGERILGI
PTVSDRIAQMVVKLEFEPQVEPHFLPDSYGYRPNKSALDAVGVTRERCWRYDWVLEFDIKGLFDNIPHDLLLKAVYKHTD
TAWVRLYIERWLTVPMQMPNGELSSRGKGTPQGGVVSPVLSNLFLHYVFDKWLQKHYSDTPWCRYADDGLVHCRSEAEAK
HMLEALKQRFQSCGLELHPVKTKIVYCKDGSRKGRYKHTSFDFLGYTFRRRLCRNRKRNSVFVNFTPAVSKAALKSMRGK
VRKLRVRTRTELSLGQIAQWLNPIIRGWIGYYGCYTRSALYGMCRHVNMTLVRWVRRKFKPLRQHKIKAMLFLEKIADQH
PNLFAHWRAGMIGAFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13526.1 reverse transcriptase Not tested PAGI-7 Protein 4e-103 52
unnamed CAD33771.1 putative reverse transcriptase Not tested PAI I 536 Protein 1e-72 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MEALZ_2163 YP_004917441.1 reverse transcriptase VFG1512 Protein 8e-73 44