Gene Information

Name : lysS (MEALZ_2010)
Accession : YP_004917290.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 2301023 - 2302519 bp
Length : 1497 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2183178, 7473706; Product type e : enzyme

DNA sequence :
ATGTCCGAACTTTTGCAAGACGAACAAGAACAAATCAGACAACGCCGCAGCAAACTGATTGAAATACGTGAGCGCGGCAT
AGCATTTCCTACGGATTTTCGTCGTAATGTCGTAGTCGGCGAACTGCTGGCGGAATACGGCGAAAAAACCAAGGAAGAAC
TCGAGGCCGAACCGATCCGCGTCAAGGTGGCCGGACGCATGATGACTCGCCGCATCATGGGCAAGGCGAGTTTCTGTCAT
ATTCAGGATATGTCGGGGCAAATGCAGCTTTATGTCGCGCGCGATCATCTGCCGGAAGGCTTTTATAACGAGCAGTTCAA
GAAATGGGACATCGGCGACATCGTCGGTGCCGAGGGCGTGTTGTTTAAGACCAATGTCGGCGAATTGAGCATCAAAGTCG
ACGATATTCGTTTATTGACCAAAGCGCTTAGGCCATTGCCTGAAAAATTCCACGGCATCGCCGATCAGGAAATCAAATAT
CGCCAGCGTTATTTGGATTTGATCATGAGCGATCAATCGCGCAAGACTTTCCTGATCCGTTCGAAAATCGTCACATACAT
TCGAGACTTCTTGGTCGCGCGACAATTTCTCGAGGTCGAAACGCCAATGATGCAGGCGATTCCCGGCGGTGCGACCGCGC
GTCCGTTCAAGACGCATCACAATGCCTTGGACATGGAGTTGTTTTTACGCATTGCGCCGGAATTGTATTTAAAACGACTG
ATCGTTGGCGGTTTCGAACGCGTTTTCGAAATCAACCGTAATTTCCGCAACGAAGGCCTGTCGACACGGCATAATCCGGA
ATTCACGATGCTTGAATTCTATCAAGCCTATGCCGAGTATCACGACTTGATGGATTTGACCGAAGAAATGGTGCGAGGCA
TTGCACTCGAAGTACTCGGCCAAACGCTGATTACTTATCAAGGCGAACACTACGACTTCGGCAAACCGTTCGATCGCATG
ACCGTGGTCGAATCGATTCTGCATTTCAATCCGGATTTGACGGTCGATGATCTCGCGACGCGCGAAGCGTCGGCGAAGGT
GGCCGAAAATTTGAAAATTCCGGTCAAGGACGGCTACGGTCTCGGTAAGCTTCAGATCGAGATCTTCGAAAAAACGGTCG
AACACCGCTTGATGAATCCGACCTTTATTACTGCGTATCCGGTCGAAGTGTCGCCATTGGCCAGACGTAACGATGATGAC
CCGCATGTGACCGACCGTTTCGAGTTTTTCGTCGGCGGGCGCGAAATCGCGAACGGTTTCACCGAGTTGAACGACGCCGA
GGATCAGGCCGAACGTTTCCGTAAACAAGTCGAGGAAAAAGAAGCCGGCGACGACGAAGCGATGCATTACGACGCCGACT
ATGTCACGGCATTGGAACACGGCATGCCCCCGACGGCGGGCGAGGGCATAGGCATCGATCGTCTGGTGATGCTGTTCACC
GACGCGCCTTCGATTCGAGATGTATTGTTATTCCCACATCTTCGGCCTAAGAATTAA

Protein sequence :
MSELLQDEQEQIRQRRSKLIEIRERGIAFPTDFRRNVVVGELLAEYGEKTKEELEAEPIRVKVAGRMMTRRIMGKASFCH
IQDMSGQMQLYVARDHLPEGFYNEQFKKWDIGDIVGAEGVLFKTNVGELSIKVDDIRLLTKALRPLPEKFHGIADQEIKY
RQRYLDLIMSDQSRKTFLIRSKIVTYIRDFLVARQFLEVETPMMQAIPGGATARPFKTHHNALDMELFLRIAPELYLKRL
IVGGFERVFEINRNFRNEGLSTRHNPEFTMLEFYQAYAEYHDLMDLTEEMVRGIALEVLGQTLITYQGEHYDFGKPFDRM
TVVESILHFNPDLTVDDLATREASAKVAENLKIPVKDGYGLGKLQIEIFEKTVEHRLMNPTFITAYPVEVSPLARRNDDD
PHVTDRFEFFVGGREIANGFTELNDAEDQAERFRKQVEEKEAGDDEAMHYDADYVTALEHGMPPTAGEGIGIDRLVMLFT
DAPSIRDVLLFPHLRPKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-146 59
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 7e-88 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_004917290.1 lysyl-tRNA synthetase VFG1668 Protein 1e-146 59