Gene Information

Name : ureC (MEALZ_1772)
Accession : YP_004917052.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Virulence
Product : urease alpha subunit
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 2038527 - 2040230 bp
Length : 1704 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1400317, 1624427, 2211515, 7721685, 7855593, 7909161, 8318888, 8808930; Product type e : enzyme

DNA sequence :
ATGAGTAAATTGAGCCGTCGGGCTTATGCCGATATGTTCGGTCCGACTACCGGAGACCGCGTGCGTTTGGCCGATAGCGA
ATTGTTTCTCGAAGTCGAGAAAGACCTGACGATCTACGGCGACGAGGTCAAATTCGGCGGCGGCAAGGTGATTCGCGACG
GCATGGGACAGAGTCAGGCCGGCTCGCAAACCGCGATGGATCTGGTGATTACGAATGCATTGATCGTCGATCATTGGGGC
ATCGTCAAGGCCGACGTCGGCATCAAAAATGGCCGTATCGCCGCGATCGGGAAGGCCGGTAATCCCGACGTGCAAGAAGG
TGTCGACATCATCATCGGGCCCGGCACCGAGATCATTGCAGGGGAAGGGCAGATACTGACCGCCGGCGGCATCGACGCGC
ACATTCATTTCATTTGTCCGCAGCAGGTCGACGAAGCGCTGATGTCCGGCGTCACGACGATGCTCGGCGGCGGTACGGGG
CCCGCGACCGGCACCAATGCGACGACTTGCACGCCGGGGCCGTGGAACATTCACCGCATGCTGCAGGCCTTGGACGGATT
GCCGATGAATTTCGGTCTGCTCGGCAAGGGCAATGCGAGTCTTCCTGAAGCGCTCGAAGAACAAATCCGCGCCGGCGCGA
TGGGTTTGAAACTGCATGAGGACTGGGGCACGACGCCGGCCGCGATCGATTGTTGTTTGTCGGTGGCCGAGCGTTTCGAC
GTGCAGGTCGCGATCCATACCGATACCTTGAACGAGTCGGGTTTCGTCGAAGATACGATCGCCGCATTCAAGGGCCGGAC
GATTCATACTTACCATACCGAAGGCGCCGGCGGCGGCCACGCGCCGGATATCATCAAGGCCTGCGGTCAGGCCAATGTCC
TACCGTCGTCGACCAATCCGACTCGGCCCTATACGATCAATACCGTCGACGAGCATCTGGACATGCTGATGGTTTGCCAT
CATCTCGATCCGGGCATACCCGAGGATGTCGCATTCGCCGAATCGCGCATCCGCCGCGAAACGATCGCGGCCGAGGATAT
TCTGCACGATCTCGGCGCGTTTTCAATGATTTCGTCCGATTCCCAGGCGATGGGGCGAGTTGGCGAAGTGATCACGCGGA
CCTGGCAGACCGCGCACAAAATGAAGGTGCAGCGCGGCAGTCTTCCGGGAGACAATGCGCGCCACGACAATTTTCGCATC
AAGCGCTATATCGCCAAATACACGATCAATCCGGCAATCAGTCATGGTATCTCGCATGAGGTCGGTTCGGTCGAAGTCGG
TAAATTAGCCGATCTGGTGCTCTGGCAGCCGGCTTTTTTCGGAGTCAAACCCAGTTTGATATTGAAAGGTGGTTTCATCG
CTGCCGCGCCGATGGGCGATCCTAATGCGTCGATTCCGACGCCGCAGCCGGTTCATTACCGGCCAATGTTCGGTTCGTTC
GGACAAGCTGCAGCGTCGACATCGATGATGTTTTTATCGCAAGCGGCTGTCGTCGCGGGGCTGGCCGATAATATTCGGCT
CGGGAAGCGCATCGGCGTTACTCGCGGGACGCGTTCGGTCGGCAAGCATTCGATGATACATAATCATTATCAACCGGTCA
TCGAAGTCGACCCGCAAACCTACGTGGTTCGCGCCGATGGGGTGTTGCTTACCTGTGAGCCTGCGGACGTGTTGCCCTTC
GCTCAACGTTATTTTCTATTTTGA

Protein sequence :
MSKLSRRAYADMFGPTTGDRVRLADSELFLEVEKDLTIYGDEVKFGGGKVIRDGMGQSQAGSQTAMDLVITNALIVDHWG
IVKADVGIKNGRIAAIGKAGNPDVQEGVDIIIGPGTEIIAGEGQILTAGGIDAHIHFICPQQVDEALMSGVTTMLGGGTG
PATGTNATTCTPGPWNIHRMLQALDGLPMNFGLLGKGNASLPEALEEQIRAGAMGLKLHEDWGTTPAAIDCCLSVAERFD
VQVAIHTDTLNESGFVEDTIAAFKGRTIHTYHTEGAGGGHAPDIIKACGQANVLPSSTNPTRPYTINTVDEHLDMLMVCH
HLDPGIPEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTAHKMKVQRGSLPGDNARHDNFRI
KRYIAKYTINPAISHGISHEVGSVEVGKLADLVLWQPAFFGVKPSLILKGGFIAAAPMGDPNASIPTPQPVHYRPMFGSF
GQAAASTSMMFLSQAAVVAGLADNIRLGKRIGVTRGTRSVGKHSMIHNHYQPVIEVDPQTYVVRADGVLLTCEPADVLPF
AQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 72
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 72
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-162 62
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-162 62
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-162 62
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-162 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004917052.1 urease alpha subunit VFG0270 Protein 3e-155 63