Gene Information

Name : guaA (MEALZ_0102)
Accession : YP_004915414.1
Strain : Methylomicrobium alcaliphilum 20Z
Genome accession: NC_016112
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 112533 - 114122 bp
Length : 1590 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3894345; Product type e : enzyme

DNA sequence :
GTGAGCCAGCAAGCATCGACCAACATTCATCTGTATAAAATCCTGATACTGGATTTCGGGTCCCAATACACCCAATTAAT
CGCCCGGAGGATACGAGAAATCGGTGTGTATTGCGAAATACTTTCTTGTGATTGCGAGATCGATGACATCATCGGATTTG
CACCGAATGGCATTATATTGTCGGGTGGTCCGGAAACGGTCACTAGCGATGATACGCCGCGTGCGCCGCAACGGGTTTTT
GCATTGGGTGTTCCGGTATTGGGTATTTGCTACGGTATGCAGACCATGACCGAGCAATTAGGCGGTAGAGTCGAGTCGTC
CAGTCATCGGGAATTCGGTTATGCGCAAATTCGCGCGCATGCGCATTCTAAGTTATTGAAAGGTATTGAAGATCATACAT
CGCCGGAAGGCTTCGGTTTGCTGGATGTGTGGATGAGTCATGGCGATAGGGTTGTCGAATTGCCGGAAGGTTTTATTCGT
ATTGCCAGTTCCGACGGAGCGCCTATTGCCGGTATCGCGCATGAAGAAAAGTTGTTTTATGGTTTGCAATTTCATCCAGA
AGTGACGCATACCCGGCAGGGTTCAAGAATACTGTCGCGTTTTGTGCTCGACATTTGCGGTTGCGAGGCGCTGTGGACGG
CCGATAATATCATCGAAGACAGTGTACATGCGGTTCGTCGTAAAGTCGGCTCCGATCGAGTGATTTTAGGGCTTTCAGGC
GGGGTGGATTCGTCGGTTGTGGCGGCTTTATTGCATGAGGCAATCGGCGATCAATTGACATGTGTGTTTGTCGATACCGG
CTTGTTGCGCTTGCACGAAGGCGATCAGGTCATGGCTACATTTGCCGAGCACATGGGCGTTCGGGTAATTAGGGTCGATG
CCGAGCAACGTTACCTAGAGGCATTGCAAGGAGTGGCGGATCCGGAGCAGAAACGAAAAATTATCGGTAACTTGTTCGTT
GAGATCTTCGATGAGGAAGCCGCTAAACTGGCCGATGCGAAATGGTTGGCGCAAGGCACGATTTATCCGGATGTGATCGA
GTCGGCGGGCGCGAAAAGCGGTAAGGCTCATTTAATCAAGTCTCACCATAACGTCGGTGGCTTGCCGGAAAATATGACGC
TTAAGTTGCTGGAACCCTTGCGTGAATTGTTCAAGGATGAGGTTAGAAAGCTTGGTTTGGAGCTTGGCTTGCCTTACGAA
ATGGTATTTCGTCATCCCTTTCCTGGGCCGGGCTTGGGTGTGCGGATTTTAGGTGAAGTCAAAAAAGACTATGCCGATTT
GTTGCGACAGGCCGATGCGATATTTATCGAAGAATTATATCGGCACCAACTGTATGAAAAGGTCAGTCAGGCATTTGCGG
TGTTTTTGCCGGTCAAGTCGGTCGGCGTAATGGGCGACGGGCGGCGTTACGATTATGTGATTGCCTTGCGCGCGGTTGAA
ACCATCGATTTCATGACGGCGCGTTGGGCGCATTTACCTTACGATTTTTTGGATTTGGTTTCGCGTCGGATCATTAACGA
AGTCTCGGGTATTTCTCGGGTGACTTACGATATTTCCGGCAAACCGCCGGCTACGATTGAGTGGGAATAG

Protein sequence :
MSQQASTNIHLYKILILDFGSQYTQLIARRIREIGVYCEILSCDCEIDDIIGFAPNGIILSGGPETVTSDDTPRAPQRVF
ALGVPVLGICYGMQTMTEQLGGRVESSSHREFGYAQIRAHAHSKLLKGIEDHTSPEGFGLLDVWMSHGDRVVELPEGFIR
IASSDGAPIAGIAHEEKLFYGLQFHPEVTHTRQGSRILSRFVLDICGCEALWTADNIIEDSVHAVRRKVGSDRVILGLSG
GVDSSVVAALLHEAIGDQLTCVFVDTGLLRLHEGDQVMATFAEHMGVRVIRVDAEQRYLEALQGVADPEQKRKIIGNLFV
EIFDEEAAKLADAKWLAQGTIYPDVIESAGAKSGKAHLIKSHHNVGGLPENMTLKLLEPLRELFKDEVRKLGLELGLPYE
MVFRHPFPGPGLGVRILGEVKKDYADLLRQADAIFIEELYRHQLYEKVSQAFAVFLPVKSVGVMGDGRRYDYVIALRAVE
TIDFMTARWAHLPYDFLDLVSRRIINEVSGISRVTYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-127 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-127 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-126 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-114 48