Gene Information

Name : lysS (SCAT_5412)
Accession : YP_004914903.1
Strain : Streptomyces cattleya NRRL 8057
Genome accession: NC_016111
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 5826599 - 5829901 bp
Length : 3303 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology

DNA sequence :
ATGGGCAGCGACGGCCGCACCACCTCGGTCACCCGGCTCCACCGGGTCACCGCACGCGTCCCCGCCTGGGTCGGCGGCTT
CTTCGGCCTGCTCGGCACGGCCTGCGCGCTCACCACGCTGATCAGCCCGCTGCGCTTCCTGCTCGATCCGGTGCTGCGGG
TGGTCAACGAATGGCTGGTGCCCGCCTCCCCGAACCTGGCGTACGCGGTCTTCCTGCTGCTGCTCGCCGGCGCGCTGCTG
GCCCGCAAACGGGCCGCGTGGTGGGTGGTCACCTTCTACACCGCGCTGCTGCTGGCCGCCGAGGCGATCACGGCGGACCT
GGTGGGCGTGGTCGAGGCGGTGGTCTCGCTGACCATCACCGGGGTCGTGCTGGCGGTGCTGCTGGTGTCCCGGTCGCAGT
TCCCGGCCCGGGTGCGGCGCGGCGCGTTCTGGCGGGCGCTGGGCGTCCTGGTGCTGGGGCTGGCGGTCTTCGTGCTGATC
GGCTGGGGGCTCACCGAACTCTTCCCCGGCGGGCTGCCGCCGGGGGTACGGCTGCTGTGGGCGGCCAACCGGGTCTGCGG
CGGGCTGATCAGCACCCGGCACTTCAACCACCACCCGCCGGTCGCCCTCGGCTTCCTGCTCGGTCTCTTCGGCGCGCTGG
CGCTGCTCAACGCCGCCGCCGTGCTCTTCCGCTCGCAGAAGGCCCAGGCCGGACTCCACGGCGACGAGGAGACCCGGATC
CGCGCCCTGCTCGCCCAGTACGGCGGCCAGGACTCGCTGGGCTACTTCGCCACCCGCCGCGACAAGGCCGTCGTCTTCGC
CCCCGGCGGCGGCGCCGCGGTCACCTACCGGGTCGAGGCCGGGGTCTGCCTGGCCAGCTCCGACCCGGTGGGGGAGCACG
GCGCCTGGGGCCCGGCCATCGACGCCTGGCTCGACCTCGCCCGCCGCTACGCCTGGACCCCGGCCGTGATGGGCGCCGGC
GAGGAAGGCGCCAAGGCGTATGCACGGGCCGGCCTCAACGCCCTGCAACTGGGTGACGAGGCCGTCCTGCACACCGCCGA
GTTCGACCTGAACGGCCGCGAGATGCGGGTCACCCGGCAAGCGGTCAACCGGGTCCGGCGCACCGGCATGACACTGCGCG
TCCGCCGCCACGGCGCGCTGACCCCGCAGGAGATGGCCGAGGTCGTCGCGCTCGCCGACGCCTGGCGCGACACCGAGGTG
GAACGCGGCTTCTCCATGGCGCTCGGCCGCCTCGGCGACCCCGCGGACGGCGACTGCCTGCTCGCCGAGGCGGTCACCGC
GCAGGGGCGCACCGTGGCGCTGCTCTCCTTCGTCCCCTGGGGACGCGACGGCATCTCGCTGGACGTGATGCGCCGCGACC
GGGCCGCGCCCAACGGCGTCATGGAGTTCATGGTCGCCGAACTGGCCGGCCACGCCACACGCCTGGGCATCCGGCGCATC
TCGCTCAACTTCGCCGTCTTCCGGGCCGTCTTCGAGCAGGGGGCACGCATCGGCGCCGGCCCGGTGCTGCGGGTCTGGCG
CAGGCTGCTGCTGTTCTTCTCCAAGTGGTGGCAGCTGGAGGCGCTCTACCGGTCCAACGTCAAGTACCGCCCCGAGTGGG
TGCCGCGCTTCCTGTGCTTCGCCGAGGCCCGGCAGATCGCCCGGATCGGGCTGGCGGCCGGCATCGCCGAGGGCTTCGTG
GAGTTCCCCCGGTTCGGCCGCCGCCGTCCCCCCTCCGGGGTGCGCCCCCCGGTCAGCGCCGCCCCGCTGCCCCCGCTCAC
CGCCCGCGAACTGGCCCTGCTCGCCGGGGAACGGGCCACCACCACCGTCGAGGACGTCTCCGCCCTGCCCGAACAGGTAC
GGGTACGCCGGGCCAAGCTCGACCGGCTGCGCGAGCAGGGCACCGACCCGTACCCGGTGCTCGCCGGGCGCACCGACACC
CTCGGCCAGGTCCTCGCCCGCCACCCCGCGCTGCCCCCCGGCACCAGGACCGGCCACCAGGTCACCGTCGCCGGCCGCGT
GCTGCGCAGCCGCGACTTCGGCGGCGTGGTCTTCGCCGTGCTGCGCGACTGGTCCGGCGACCTCCAGATCGCGCTCACCC
GGGCCGACTCCGGCGAGGAGGAGCTGCGCCGCTTCACCTCCGACACCGACCTCGGCGACCATCTGGAGGTCACCGGTGAG
GTGGGCGCCAGCGACCGCGGCGAGCCCACCGTCTTCGTCCACTCCTGGCGCATGACGGCCAAGTGCCTGCGCCCGCTGCC
CGACAAGCGCCGCGGCCTGACCGACCCGGAGGCCCGGGTCCGCCGCCGCTACGTCGACCTGGTGGTCCGCCCCGAGGCCC
GCGAGGTGCTGCGGGTGCGCGGCGCGGCGGTGCGGGCGTTGCGCGAACAACTCGCCGCCCGGGACTACCTGGAGGTGGAG
ACCCCCATGCTCCAGCAGGTGCACGGCGGCGCCAACGCCCGTCCGTTCACCACCCACATGCACGCCTACGGCCTCGACCT
GTACCTGCGCATCGCCCCCGAGCTGTATCTCAAACGACTCTGCGTCGGCGGCGTGGAGCGCGTCTTCGAACTCGGCCGCA
CCTTCCGCAACGAAGGCACCTCCTACAAGCACAACCCCGAGTTCACCATGCTGGAGGCGTACCAGGCGTTCGCCACTTAC
GACGACATGCTCCAGCTGACCCGGGAGCTGATCCAGGCCGCCGCCACCGCCGCGTACGGCACCCCCGTCGCGCGCCGCAC
CGCCCCGGACGGCACCGCGGTGGAGTACGACATCTCCGGCGAGTGGCCGGTGCGCACCGTCTACGGCGCGCTCGGCGAGG
CGCTGGGCGAACCGGTGGGCCCGGACACCCCGGTGCACACCCTGATCGAGCTGTGCGACCGGGCCGGGGTACCGCACCAG
CCGGGGATGACCCACGGCGAGCTGGTGCTGGAGATGTACGAGCGCCTGGTGGAGGAGGCCACCACGCTGCCCACGTTCTA
CAAGGACTTCCCCACCGACGTCTCCCCGCTGACCCGGCAGCACCGCACCGACCCCCGGCTCGCCGAACGCTGGGACCTGG
TCGCCTTCGGCACCGAACTGGGCACCGCCTACTCGGAGTTGACCGACCCGGTGGAACAGCGCAAACGCCTCACCAAGCAG
TCCCTGCTGGCGGCCGGGGGCGACCCGGAGGCGATGGAGGTCGACGAGGACTTCCTGACCGCCCTGGAGTACGCCATGCC
GCCCACCGGCGGGCTCGGGCTCGGCGTCGACCGGCTGGTGATGTTCCTGACCGGGCTGTCGATCCGCGACACGCTCCCGT
TCCCGCTCGTCCGCCGTCGCTGA

Protein sequence :
MGSDGRTTSVTRLHRVTARVPAWVGGFFGLLGTACALTTLISPLRFLLDPVLRVVNEWLVPASPNLAYAVFLLLLAGALL
ARKRAAWWVVTFYTALLLAAEAITADLVGVVEAVVSLTITGVVLAVLLVSRSQFPARVRRGAFWRALGVLVLGLAVFVLI
GWGLTELFPGGLPPGVRLLWAANRVCGGLISTRHFNHHPPVALGFLLGLFGALALLNAAAVLFRSQKAQAGLHGDEETRI
RALLAQYGGQDSLGYFATRRDKAVVFAPGGGAAVTYRVEAGVCLASSDPVGEHGAWGPAIDAWLDLARRYAWTPAVMGAG
EEGAKAYARAGLNALQLGDEAVLHTAEFDLNGREMRVTRQAVNRVRRTGMTLRVRRHGALTPQEMAEVVALADAWRDTEV
ERGFSMALGRLGDPADGDCLLAEAVTAQGRTVALLSFVPWGRDGISLDVMRRDRAAPNGVMEFMVAELAGHATRLGIRRI
SLNFAVFRAVFEQGARIGAGPVLRVWRRLLLFFSKWWQLEALYRSNVKYRPEWVPRFLCFAEARQIARIGLAAGIAEGFV
EFPRFGRRRPPSGVRPPVSAAPLPPLTARELALLAGERATTTVEDVSALPEQVRVRRAKLDRLREQGTDPYPVLAGRTDT
LGQVLARHPALPPGTRTGHQVTVAGRVLRSRDFGGVVFAVLRDWSGDLQIALTRADSGEEELRRFTSDTDLGDHLEVTGE
VGASDRGEPTVFVHSWRMTAKCLRPLPDKRRGLTDPEARVRRRYVDLVVRPEAREVLRVRGAAVRALREQLAARDYLEVE
TPMLQQVHGGANARPFTTHMHAYGLDLYLRIAPELYLKRLCVGGVERVFELGRTFRNEGTSYKHNPEFTMLEAYQAFATY
DDMLQLTRELIQAAATAAYGTPVARRTAPDGTAVEYDISGEWPVRTVYGALGEALGEPVGPDTPVHTLIELCDRAGVPHQ
PGMTHGELVLEMYERLVEEATTLPTFYKDFPTDVSPLTRQHRTDPRLAERWDLVAFGTELGTAYSELTDPVEQRKRLTKQ
SLLAAGGDPEAMEVDEDFLTALEYAMPPTGGLGLGVDRLVMFLTGLSIRDTLPFPLVRRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-157 44
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-157 44
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-156 44
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 2e-157 44