Gene Information

Name : ureC (SCAT_4358)
Accession : YP_004913857.1
Strain : Streptomyces cattleya NRRL 8057
Genome accession: NC_016111
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 4670999 - 4672738 bp
Length : 1740 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12401490, 16199586, 9287005; Product type e : enzyme

DNA sequence :
ATGAGCCGCACCACCGGCAGCTCGCACCTGAACCGGCACACCGACACCCGTACCACCGTCGACCCGCACGAGTACGCCGC
CACCTACGGGCCCCGGGCCGGCGACCGGATCCGGCTCGGCGACACTGGGCTGGTGATCCGCGTCGAATCCGACGCCCAGC
GGCCCGGCGACGAATTCCTCGCCGGCTTCGGCAAGACCGCCCGCGACGGACTCCACCTCAAGGCCGCCGCCGTCCGCGAC
ACCTGCGACGTGGTCATCAGCAACGTCGTCGTCATCGACGCCGCCCAGGGCGTCCGCAAGGTCTCCATCGGCATCCGCGA
GGGCCGCATCCACGCCATCGGCCGGGCCGGCAACCCCGACACCCTCGACGGGGTGGACGTGGTGGTGGGCACCGGCACCA
CCATCGTCTCCGGCGAGGGCATGATCGCCACCGCCGGCGCCGTGGACACCCACGTCCACCTGCTCTCGCCACGCGTCATG
GAGGCGTCGCTGGCCTCCGGGGTGACCACCGTCATCGGCCAGGAGTTCGGCCCGGTGTGGGGCGTGGGCGTCAACTCCCC
GTGGGCGCTGCGCCACGCGGTGAACGCCTTCGACGCCTGGCCGGTCAACATCGGCTTCCTGGCCCGCGGTTCGTCCTCCG
ACCCCGCCCCGCTGGTGGAGGCGCTGGCCGAGGGGGGCGCCTGCGGCTTCAAGGTCCACGAGGACATGGGCGCCCACGCC
CGCGCCCTGGACACCGCGCTGCGGGTGGCCGAGGACCACGACGTCCAGGTCGCCCTCCACTCCGACGGCCTCAACGAGTG
CCTGACCGTCGAGGACACCCTGCGCGTGCTGGACGGGCGCACCATCCACGCCTTCCACATCGAGGGCTGCGGCGGCGGCC
ACGTCCCCAACGTGCTCAAGATGGCCGGGGTCGGCAACGTCATCGGCTCCTCGACCAACCCCACGCTCCCCTTCGGCCGG
GACGCGGTCGCCGAGCACTACGGCATGATCGTCTCCGTCCACGGCCTCAAGCCCGACCTGCCCGGCGACGCCGCCATGGC
CCGCGACCGCATCCGGGCCGGCACCATGGGCGCCGAGGACGTCCTGCACGACCTCGGGGCGATCGGCATCACCTCCTCCG
ACGCCCAGGGCATGGGGCGGGCCGGGGAGACGGTGGCCCGCACCTTCGCCATGGCCGCCAAGATGAAGGCCGAGACCGGA
CCGCTCCCCGGCGACGGCCCCGCCGACGACAACGGCCGCGTCCTGCGCTACATCGCCAAGCTCACCATCAACCCGGCCAT
CGCCCACGGCCTCGCCCACGAGATCGGCTCCATCGAGACCGGCAAGCTCGCCGACATCGTGCTGTGGCACCCGCGCTACT
TCGGCGCCAAACCGCAGCTGGTGCTCAAGGCCGGCTTCCCCGCCTACGGCGTCACCGGCGACCCCAACGCCGCCACCGAC
ACCTGCGAACCCCTCGTGCTGGGACCGCAGTTCGGGGCCTACGGCGCCACCGCCGCCGACCTGTCGGTGGTCTTCACCGC
CTCCGCCGCGGCCGAGGCGGCCGGTGACCGGATGCCCACCAGGCGCCGCCGGGTCGCGGTCCGCGGCACCCGCGGCATCG
GCCCCGCCGACCTGGTGCTCAACTCCCGCACCGGCAGCGTCGACGTCGACCCCCGCAGCGGCCTGGTCACCCTCGACGGG
GAACCGCTCCGCTCCGACCCGGCCGAACAGGTCGCCCTGTCCCGGCTGTACTTCCTGTGA

Protein sequence :
MSRTTGSSHLNRHTDTRTTVDPHEYAATYGPRAGDRIRLGDTGLVIRVESDAQRPGDEFLAGFGKTARDGLHLKAAAVRD
TCDVVISNVVVIDAAQGVRKVSIGIREGRIHAIGRAGNPDTLDGVDVVVGTGTTIVSGEGMIATAGAVDTHVHLLSPRVM
EASLASGVTTVIGQEFGPVWGVGVNSPWALRHAVNAFDAWPVNIGFLARGSSSDPAPLVEALAEGGACGFKVHEDMGAHA
RALDTALRVAEDHDVQVALHSDGLNECLTVEDTLRVLDGRTIHAFHIEGCGGGHVPNVLKMAGVGNVIGSSTNPTLPFGR
DAVAEHYGMIVSVHGLKPDLPGDAAMARDRIRAGTMGAEDVLHDLGAIGITSSDAQGMGRAGETVARTFAMAAKMKAETG
PLPGDGPADDNGRVLRYIAKLTINPAIAHGLAHEIGSIETGKLADIVLWHPRYFGAKPQLVLKAGFPAYGVTGDPNAATD
TCEPLVLGPQFGAYGATAADLSVVFTASAAAEAAGDRMPTRRRRVAVRGTRGIGPADLVLNSRTGSVDVDPRSGLVTLDG
EPLRSDPAEQVALSRLYFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-92 46
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-92 46
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 8e-92 46
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-92 46
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 6e-96 45
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 6e-96 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004913857.1 urease subunit alpha VFG0270 Protein 2e-88 42