Gene Information

Name : pyk (SCAT_4244)
Accession : YP_004913743.1
Strain : Streptomyces cattleya NRRL 8057
Genome accession: NC_016111
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 4540546 - 4541976 bp
Length : 1431 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10559165, 10932722, 10966427, 11489127, 17022686; Product type e : enzyme

DNA sequence :
ATGCGCCGAGCCAAAATCGTCTGCACCCTGGGTCCCGCCGTCGACTCCTACGACCAGCTCAAGGCGCTGGTCGAGGCCGG
GATGAACGTGGCCCGCTTCAACTTCAGCCACGGCACCCACGCCGAGCACGAGGAGCGGTACCACCGCGTGCGCAAGGTCG
CCGAGGAGAGCGGCCAGGCGGTGGGCGTCCTCGCCGACCTCCAGGGGCCCAAGATCCGCCTGGAGACCTTCGCCGACGGC
CCGGTGGAGCTGGTGGCGGGCGACGAGTTCACCATCACCACCGAGGACGTCCCCGGCGACAAGCACCTCTGCGGCACCAC
CTACAAGGGCCTCCCCGGTGACGTCAGCCAGGGCGACCCGGTGCTGATCAACGACGGCAACGTGGCGCTGCGGGTGGTCG
AGGTGACCGGTACCCAGGTGCGCTGCCTGGTGGTCGAGGGCGGCATCGTCTCCGACCACAAGGGCATCAACCTGCCCGGT
ACCGCCGTCAACGTCCCGGCGCTGTCCGAAAAGGACGTGGAGGACCTGCGGTTCGCCCTGCGCATGGGCGTGGACATGGT
GGCCCTCTCCTTCGTCCGGGACGCCAAGGACGTCCGCGACGTGCACCGCGTGATGGACGAGGAGGGGCGCCGCGTCCCGG
TCATCGCCAAGGTGGAGAAGCCTCAGGCGGTGGAGAACATGGAGGACGTGGTCGCCGCCTTCGACGGCGTCATGGTGGCC
CGCGGCGACCTCGCCGTGGAGTACCCGCTGGAGAAGGTGCCGGTGGTGCAGAAGCGGCTGGTCGAGCTGTGCCGCCGCAA
CGCCAAGCCGGTGATCGTCGCCACCCAGATGATGGAGTCGATGATCAACTCCTCCCGGCCGACCCGCGCCGAGGCGTCCG
ACGTGGCCAACGCGGTGCTCGACGGCGCCGACGCGGTGATGCTGTCGGCCGAGTCCTCGGTCGGCAAGTACCCGATCGAG
ACCGTCAAGACGATGTCCCGGATCGTGGTGGCCGCCGAGACCGAGCTGCTCAAGCGGGGGCTCCAGCCGCTGGCGCCGGG
CAAGAAGCCGCGCACCCAGGGCGGCGCGGTGGCCAGGGCCGCCGCCGAACTCGCCGACTTCCTCGACGCCAAGACGCTGG
TGGCCTTCACCAAGTCCGGTGACACCGCCCGCCGGCTCGCCCGCTACCGGGTCCCGGCGCCGGTGCTCGCCTTCACCACC
GACGCCGCCACCCGCAACCAGCTCGCCCTCACCTGGGGGGTCAGCACGCACCTGGTGCGCCACGTCGACCACACCGACGC
CATGGTGGACCTGGTCGACCAGGAGATGCTCAAGCTCAGCGAGTACACCAAGGGCGACACCGTGATCATCACGGCCGGCT
CCCCGCCCGGCGTCCCCGGCACCACCAACCTGGTGCGCGTCCACCACCTCGGCGAGCGCGACAGCGACTGA

Protein sequence :
MRRAKIVCTLGPAVDSYDQLKALVEAGMNVARFNFSHGTHAEHEERYHRVRKVAEESGQAVGVLADLQGPKIRLETFADG
PVELVAGDEFTITTEDVPGDKHLCGTTYKGLPGDVSQGDPVLINDGNVALRVVEVTGTQVRCLVVEGGIVSDHKGINLPG
TAVNVPALSEKDVEDLRFALRMGVDMVALSFVRDAKDVRDVHRVMDEEGRRVPVIAKVEKPQAVENMEDVVAAFDGVMVA
RGDLAVEYPLEKVPVVQKRLVELCRRNAKPVIVATQMMESMINSSRPTRAEASDVANAVLDGADAVMLSAESSVGKYPIE
TVKTMSRIVVAAETELLKRGLQPLAPGKKPRTQGGAVARAAAELADFLDAKTLVAFTKSGDTARRLARYRVPAPVLAFTT
DAATRNQLALTWGVSTHLVRHVDHTDAMVDLVDQEMLKLSEYTKGDTVIITAGSPPGVPGTTNLVRVHHLGERDSD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-80 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-80 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-80 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-79 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004913743.1 pyruvate kinase VFG0479 Protein 3e-80 41