Gene Information

Name : dhaS (SCAT_3804)
Accession : YP_004913305.1
Strain : Streptomyces cattleya NRRL 8057
Genome accession: NC_016111
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase dhaS
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4079064 - 4080518 bp
Length : 1455 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology

DNA sequence : 
ATGGCATTCGAGTACGCGCCCGCCCCGGAATCGCGCGCGGTGGTCGACATCGCGCCGTCCTACGGGCTCTTCATCGACGG
CGAGTTCACCGAGGGCGCCCAGGGGATCCTCGACAAGACGGTCTCCCCCGCCACCGAGGAGGTGCTCGCCGAGTACACCC
GGGGCGGCGCCGAGGACGTGGACCGGGCGGTGCGCGCCGCCCGCAAGGCGTTCGAGAGCTGGTCGGCGCTGCCGGGCCGG
GAGCGCGCCAAGTACCTGTTCCGGATCGCCCGGATCGTCCAGGAGCGCTCGCGTGAGCTGGCGGTGCTGGAGACGCTGGA
CAACGGCAAGCCGATCCGCGAGTCCCGCGACACCGACCTGCCGCTGGTCGCCGCGCACTTCTTCTACTACGCGGGGTGGG
CCGACAAGCTCTCCTACGCCGGCTTCGGGGAGAACCCGCGTCCGCTGGGCGTGGCCGGCCAGGTCATCCCGTGGAACTTC
CCGCTGCTGATGCTGGCGTGGAAGATCGCCCCGGCGCTGGCCTGCGGCAACACCGTGGTGCTCAAGCCGGCCGAGACGAC
CCCGCTGTCGGCGCTGTTCTTCGCGGACATCTGCCGTCAGGCCGGGCTGCCCAAGGGCGTGGTCAACATCGTCACCGGGG
ACGGCGCCACCGGTGCCGCGCTGGTGGCCCACCCGGGCGTGGACAAGGTGGCCTTCACCGGTTCCACCGAGGTCGGCAAG
GCGATCGCCCGTACCGTCGCCGGGACCGGCAAGAAGGTCACCCTGGAGCTGGGCGGCAAGGCGGCCAACATCGTCTTCGA
CGACGCGCCGATCGACCAGGCGGTCGAGGGGATCGTCAACGGGATCTTCTTCAACCAGGGCCATGTGTGCTGCGCCGGTT
CCCGGCTGCTGGTCCAGGAGTCGGTCGCCGACGAGCTGCTGGACGCGCTCAAGCGGCGGATGGCCACCTTGCGGGTGGGC
GACCCGCTGGACAAGAACACCGACATCGGCGCCGTCAACTCCGCCGAGCAGCTGGCCCGGATCACCGAGCTGGCGCGGTC
CGGCGAGGAGGAGGGCGCCGAGCGCTGGTCGCCGGCGTGCGAACTCCCGGACAGCGGCTACTGGTTCGCGCCGACCCTGT
TCACCGGGGTCACCCAGGCGCACCGGATCGCCCGCGAGGAGATCTTCGGCCCGGTGCTGTCGGTGCTGACCTTCCGTACC
CCCGCCGAGGCCGTGGAGAAGGCCAACAACACCCCGTACGGGCTGTCGGCGGGCATCTGGACGGAGAAGGGGTCGCGCAT
CCTGTGGATGGCCGACAAGCTCCGGGCCGGGGTGGTGTGGGCCAACACGTTCAACAAGTTCGACCCGACGTCGCCGTTCG
GCGGCTACAAGGAGTCGGGCTACGGCCGCGAGGGCGGCCGGCACGGTCTGGAGGCGTACCTCGCCCCGTCGAAGCCGAAG
GCGAGTGAAGAATGA

Protein sequence : 
MAFEYAPAPESRAVVDIAPSYGLFIDGEFTEGAQGILDKTVSPATEEVLAEYTRGGAEDVDRAVRAARKAFESWSALPGR
ERAKYLFRIARIVQERSRELAVLETLDNGKPIRESRDTDLPLVAAHFFYYAGWADKLSYAGFGENPRPLGVAGQVIPWNF
PLLMLAWKIAPALACGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNIVTGDGATGAALVAHPGVDKVAFTGSTEVGK
AIARTVAGTGKKVTLELGGKAANIVFDDAPIDQAVEGIVNGIFFNQGHVCCAGSRLLVQESVADELLDALKRRMATLRVG
DPLDKNTDIGAVNSAEQLARITELARSGEEEGAERWSPACELPDSGYWFAPTLFTGVTQAHRIAREEIFGPVLSVLTFRT
PAEAVEKANNTPYGLSAGIWTEKGSRILWMADKLRAGVVWANTFNKFDPTSPFGGYKESGYGREGGRHGLEAYLAPSKPK
ASEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-71 43
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 1e-47 42
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 1e-48 42
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 2e-47 42
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 2e-48 42
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 2e-48 42
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 2e-48 42
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 1e-48 42
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 1e-62 42
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 7e-48 41
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 7e-48 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-72 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-72 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-72 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-72 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhaS YP_004913305.1 aldehyde dehydrogenase dhaS VFG0082 Protein 4e-71 43