Gene Information

Name : ureC (SCAT_0338)
Accession : YP_004909883.1
Strain : Streptomyces cattleya NRRL 8057
Genome accession: NC_016111
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 400346 - 402067 bp
Length : 1722 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12401490, 16199586, 9287005; Product type e : enzyme

DNA sequence :
ATGCGTGAACTGAGCCGCCCCGCCTACGCCGACCTGTTCGGCCCCACCACCGGCGACCGCGTCCGCCTCGCCGACACGGC
CCTGTTCGTGGAGATCGAACGTGATCTCTCCGGCGGCCCCGGCGCCTCCGGCGACGAAGCGGTCTTCGGCGGCGGCAAGG
TGATCCGCGAATCCATGGGCCAGTCCCGCCTCACCCGGGCCCAGGGCGCCCCGGACACCGTGATCACCGGCGCGATCGTG
CTCGACCACTGGGGCGTGGTCAAGGCCGACGTGGGCATCCGCGACGGCCGGATCACCGCCCTGGGCAAGGCCGGCAACCC
CGAGACCATGGACGGGGTCCACCCCGCGCTGGTGATCGGCCCGGAGACGGAGATCATCGCCGGCAACGGCCGGATCCTCA
CGGCCGGCGCCATCGACGCCCACGTCCACTTCATCTGCCCGCAACTGGTCGACGAGGCGCTGGCGGCCGGGGTCACCACG
CTGGTGGGCGGCGGCACCGGCCCCGCCGAGGGCAGCAAGGCCACCACCATCACCCCGGGCGCCTGGCATCTGGCCCGGAT
GTTCGAGGCGATGGAGGACCTCCCGGTCAACGTCGGTCTGCTGGGCAAGGGCAACACCGTCAGCAGCGAGTCGATGTACG
ACCAACTGCGGGCCGGGGCCGTGGGCTTCAAGATCCACGAGGACTGGGGGGCCACCCCGGCGGTCATCGACGCCTGCCTG
ACCGTCTGCGACGCCACCGGCGCCCAGGTCGCCATCCACACCGACACCCTCAACGAGGCCGGGTTCGTGGAGGACACCCT
CGCCGCCATCGCCGGCCGGGGCATCCACGCCTACCACACCGAAGGCGCCGGCGGCGGCCACGCACCCGACATCATCACCG
TGGTCTCCCGGCCCAACGTGCTGCCCTCGTCCACCAACCCCACCCGCCCGCACACCGCCAACACCGTCGAGGAACACCTC
GACATGCTGATGGTCTGCCACCACCTCAACCCGGCCGTCCCGGAGGACCTGGCGTTCGCCGAGTCCCGCATCCGGCCGTC
CACCATCGCGGCCGAGGACGTGTTGCACGACCTCGGGGCGATCTCCATCATCTCCTCCGACTCGCAGGCGATGGGCCGCA
TCGGCGAAGTGGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAGGAACGCCGCGGCGCCCTGCCCGGCGACGGCGCC
GCCGACAACCACCGGGCCCGTCGCTACGTCGCCAAGTACACCATCAACCCGGCGATCGCCCAGGGCCTGGACGACGAGAT
CGGCTCGGTGGAGCCGGGCAAACTCGCCGACCTCGTGCTGTGGGACCCGGCGTTCTTCGGCGTCAAGCCCCAACTCGTCG
TCAAGGGCGGCCAGATCGCCTACGCGCAGATGGGCGACGCCAACGCCTCCATCCCGACCCCGCAGCCGGTCCTGCCACGG
CCGATGTTCGGCGCCACCGGACGCGCCGCCGCCTCCGGCTCGTTCAACTTCGTCACCCCCACCGCACTCGACGCCGGCCT
GTCCGAACGGCTGGGCCTGCGCAAGGAGTTCCGCGCCATCCGCAGCACCCGCGGTGTCACCAAGGCCGACATGCGGGAGA
ACGACGCCATGCCGGACGTGGTGGTCGACCCCGACACCTTCACCGTACGCATCGACGGCCAGGTGGTGGAGGCGCGGCCG
GCCGAGAAACTCCCCATGGCCCAGCGGTACTTCCTGTTCTGA

Protein sequence :
MRELSRPAYADLFGPTTGDRVRLADTALFVEIERDLSGGPGASGDEAVFGGGKVIRESMGQSRLTRAQGAPDTVITGAIV
LDHWGVVKADVGIRDGRITALGKAGNPETMDGVHPALVIGPETEIIAGNGRILTAGAIDAHVHFICPQLVDEALAAGVTT
LVGGGTGPAEGSKATTITPGAWHLARMFEAMEDLPVNVGLLGKGNTVSSESMYDQLRAGAVGFKIHEDWGATPAVIDACL
TVCDATGAQVAIHTDTLNEAGFVEDTLAAIAGRGIHAYHTEGAGGGHAPDIITVVSRPNVLPSSTNPTRPHTANTVEEHL
DMLMVCHHLNPAVPEDLAFAESRIRPSTIAAEDVLHDLGAISIISSDSQAMGRIGEVVLRTWQTAHVMKERRGALPGDGA
ADNHRARRYVAKYTINPAIAQGLDDEIGSVEPGKLADLVLWDPAFFGVKPQLVVKGGQIAYAQMGDANASIPTPQPVLPR
PMFGATGRAAASGSFNFVTPTALDAGLSERLGLRKEFRAIRSTRGVTKADMRENDAMPDVVVDPDTFTVRIDGQVVEARP
AEKLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-164 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-164 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 5e-153 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-153 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-153 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-153 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004909883.1 urease subunit alpha VFG0270 Protein 1e-138 56