Gene Information

Name : clpC (SCAT_2618)
Accession : YP_004912128.1
Strain : Streptomyces cattleya NRRL 8057
Genome accession: NC_016111
Putative virulence/resistance : Virulence
Product : class III stress response-related ATPase, AAA+ superfamily
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2743327 - 2745795 bp
Length : 2469 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12354604, 15529410, 16525504; Product type f : factor

DNA sequence :
ATGCTCAACCACAACTACATCGGCACCGAGCACATCCTCCTGGGTCTGATCCACGAGGGTGAGGGTGTCGCCGCTAAGGC
CCTGGAGAGCCTCGGCATTTCGCTTGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGT
CCGGCCACATCCCCTTCACCCCTCGTGCCAAGAAGGTCCTGGAGCTGTCGCTCCGTGAGGCCCTCCAGCTCGGCCACAAC
TACATCGGTACGGAGCACATCCTGCTCGGCCTGATCCGCGAGGGTGAGGGCGTGGCCGCGCAGGTGCTGGTGAAGCTTGG
CGCCGACCTCAACCGGGTGCGGCAGCAGGTCATCCAGCTCCTGTCGGGTTACCAGGGCGGCAAGGAGTCGGCCACGGCCG
GCGGCCCCGCCGAGGGCACCCCGTCCACTTCCCTGGTGCTCGACCAGTTCGGCCGCAACCTGACGCAGGCCGCCCGCGAG
ACCAAGCTCGACCCGGTGATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGTACCAAGAACAA
CCCCGTCCTCATCGGCGAGCCCGGCGTCGGCAAGACCGCCGTGGTCGAGGGGCTGGCCCAGGCCATCGTCAAGGGCGAGG
TCCCCGAGACGCTGAAGGACAAGCAGCTCTACACCCTCGACCTGGGCGCCCTGGTGGCCGGCTCCCGGTACCGCGGTGAC
TTCGAGGAGCGCCTGAAGAAGGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACAC
CCTGGTGGGTGCGGGCGCCGCCGAGGGCGCGATCGACGCCGCCAGCATCCTCAAGCCGATGCTCGCCCGCGGTGAGCTCC
AGACCATCGGCGCCACCACGCTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTGGAGCGCCGCTTCCAGCCG
ATCCAGGTCGCCGAGCCGTCGCTCCCGCACACCATCGAGATCCTCAAGGGCCTGCGGGACCGCTACGAGGCCCACCACCG
CGTCTCCATCACCGACGCGGCGCTGGTCGCGGCGGCCACCCTGGCCGACCGCTACATCTCCGACCGCTTCCTGCCGGACA
AGGCGATCGACCTGATCGACGAGGCGGGCTCGCGGATGCGCATCCGCCGGATGACCGCCCCGCCGGACCTGCGCGAGTTC
GACGAGAAGATCGCGGACGTGCGCCGGGAGAAGGAGTCGGCCATCGACTCCCAGGACTTCGAGAAGGCCGCGTCGCTGCG
CGACAAGGAGAAGCAGCTCCTGGCCGCGAAGACCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCG
AGGTGGACGAGGAGCTGATCGCCGAGGTCCTGGCGACCGCCACCGGCATCCCGGTCTTCAAGCTCACCGAGGAGGAGTCC
TCGCGTCTGCTGCGCATGGAGGACGAGCTCCACAAGCGCGTCATCGGGCAGAAGGACGCCATCAAGGCGCTCTCCCAGGC
CATCCGGCGTACCCGGGCCGGCCTGAAGGACCCGAAGCGTCCCGGCGGTTCGTTCATCTTCGCCGGCCCCTCCGGCGTCG
GTAAGACCGAGCTGTCCAAGACGCTGGCGGAGTTCCTCTTCGGCGACGAGGACGCGCTGATCCAGCTCGACATGTCGGAG
TTCAGCGAGAAGCACACCGTCTCCCGGTTGTTCGGCTCGCCCCCCGGCTACGTCGGCTACGAGGAGGGCGGCCAGCTCAC
CGAGAAGGTGCGCCGCAAGCCGTTCTCCGTGGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGACATCTTCAACTCGC
TGTTGCAGATCCTGGAGGACGGTCGGCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGGTCATCATCATG
ACCACCAACCTCGGTACCCGGGACATCTCCAAGGGCTTCAACCTCGGCTTCGCCGCCGCGGGTGACGTCAAGACCGGGTA
TGAGCGGATGAAGGCCAAGGTCGGCGAGGAGCTCAAGCAGCACTTCCGCCCCGAGTTCCTCAACCGTGTGGACGACATCG
TGGTCTTCCACCAGCTCACCGAGGACGACATCATCCAGATCGTCGACCTGATGATCGCCCGCGTCGACGAGCGGCTGAAG
GACCGGGACATGGGCATCGAGCTCAGCCCCGAGGCCAAGAAGCTGCTCGCCAAGAAGGGCTACGACCCGATCCTGGGCGC
CCGGCCGCTGCGTCGGACGATCCAGCGCGAGATCGAGGACCAGCTCTCCGAGAAGATCCTCTTCAACGAACTGCGCCCCG
GTCACATCGTGGTCGTCGGCACCGAGGGCGAGGGTGAGGAGAAGAAGTTCACCTTCCGCGGTGAGGAGAAGGTGACCGTC
GCCGACGCCCCGCCCATCGAGGCGGCCGGCAGCGGCGGCAGTGGCCCCAACCTCTCCAAGGACGTCTGA

Protein sequence :
MLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHN
YIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGGKESATAGGPAEGTPSTSLVLDQFGRNLTQAARE
TKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLKDKQLYTLDLGALVAGSRYRGD
FEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGATTLDEYRKHLEKDAALERRFQP
IQVAEPSLPHTIEILKGLRDRYEAHHRVSITDAALVAAATLADRYISDRFLPDKAIDLIDEAGSRMRIRRMTAPPDLREF
DEKIADVRREKESAIDSQDFEKAASLRDKEKQLLAAKTKREKEWKAGDMDVVAEVDEELIAEVLATATGIPVFKLTEEES
SRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELSKTLAEFLFGDEDALIQLDMSE
FSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILEDGRLTDSQGRVVDFKNTVIIM
TTNLGTRDISKGFNLGFAAAGDVKTGYERMKAKVGEELKQHFRPEFLNRVDDIVVFHQLTEDDIIQIVDLMIARVDERLK
DRDMGIELSPEAKKLLAKKGYDPILGARPLRRTIQREIEDQLSEKILFNELRPGHIVVVGTEGEGEEKKFTFRGEEKVTV
ADAPPIEAAGSGGSGPNLSKDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 76
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-93 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004912128.1 class III stress response-related ATPase, AAA+ superfamily VFG0079 Protein 0.0 62
clpC YP_004912128.1 class III stress response-related ATPase, AAA+ superfamily VFG0080 Protein 1e-149 52