Gene Information

Name : metB (KSE_47320)
Accession : YP_004906468.1
Strain : Kitasatospora setae KM-6054
Genome accession: NC_016109
Putative virulence/resistance : Resistance
Product : putative cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 5232869 - 5234023 bp
Length : 1155 bp
Strand : +
Note : protein synonym:O-succinylhomoserine (thiol)-lyase

DNA sequence :
ATGACCGAGCACCAGCTTTCCCACGGCTTCGAGACCCTCGCCATCCACGCGGGGCAGGAAGCGGACCCCCGGACCGGGGC
AGTCGTGACGCCGATCTACCAGGTGTCCACCTACAAGCAGGACGGCGTCGGCGGACTGCGCGAGGGCTACGAGTACAGCC
GCTCCGCCAACCCGACCCGCACCGCGCTGGAGGAGTGCCTGGCCGCGATCGAGGGCGGCGCGCGCGGCCTCGCCTTCGCC
TCCGGGCTGGCCGCCGAGGACACCCTGCTGCGCACCCTGCTCAAGCCCGGCGACCACATCGTCATCCCGAACGACGCGTA
CGGCGGCACCTTCCGGCTGTTCGCCAAGGTGCTGACCCGCTGGGGCGTCGAGTTCTCCGTCGCCGACACGCACCACCCGG
AGAAGGTCCGCGAGGCGATCCGGCCGACCACCCGCGCGGTGTGGGTGGAGACCCCGTCCAACCCGCTGCTCGGCATCACC
GACCTGGCCGCCGTCGCCGACATCGCGCACACCGCCGGCGCGAAGCTGGTCGTCGACAACACCTTCGCCAGCCCCTACCT
GCAGCAGCCGATCGCGTTCGGCGCGGACGTCGTGGTGCACTCCACCACCAAGTACATGGGCGGGCACTCGGACGTGGTCG
GCGGCGCCCTGGTGGTGGCCGACCCGGGCCTGGCCGAGGAGGTCGCCTACCACCAGAACGCGATGGGCGCGGTGGCCGGG
CCGTTCGACTCCTGGCTGGTGCTGCGCGGCATCAAGACGCTCGGCGTCCGGATGGACCGGCACTCGGAGAACGCCGAGAA
GGTCGCCGAACTGCTGTCCGGCCACCCGAAGGTGACCCAGGTGCTCTACCCCGGCCTGCCCACCCACGCCGGGCACGACA
TCGCCGCCAAGCAGATGAAGGCGTTCGGCGGCATGGTGTCGTTCCGCGTCGCGGGCGGCGAGCAGGCGGCCGTCGAGGTC
TGCAACCGGGCCGAACTCTTCACCCTGGGCGAGTCGCTGGGCGGCGTCGAGTCGCTGATCGAGCACCCCGGCCGGATGAC
CCACGCCTCCGCGGCCGGCTCCCCGCTGGAGGTGCCCGCCGACCTGGTGCGGATCTCGGTCGGCATCGAGGCCGCCGCCG
ACCTGCTCGCCGACCTGGAGCAGGCGCTCGGCTGA

Protein sequence :
MTEHQLSHGFETLAIHAGQEADPRTGAVVTPIYQVSTYKQDGVGGLREGYEYSRSANPTRTALEECLAAIEGGARGLAFA
SGLAAEDTLLRTLLKPGDHIVIPNDAYGGTFRLFAKVLTRWGVEFSVADTHHPEKVREAIRPTTRAVWVETPSNPLLGIT
DLAAVADIAHTAGAKLVVDNTFASPYLQQPIAFGADVVVHSTTKYMGGHSDVVGGALVVADPGLAEEVAYHQNAMGAVAG
PFDSWLVLRGIKTLGVRMDRHSENAEKVAELLSGHPKVTQVLYPGLPTHAGHDIAAKQMKAFGGMVSFRVAGGEQAAVEV
CNRAELFTLGESLGGVESLIEHPGRMTHASAAGSPLEVPADLVRISVGIEAAADLLADLEQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-77 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-78 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-58 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_004906468.1 putative cystathionine gamma-synthase BAC0207 Protein 9e-60 42