Gene Information

Name : Acin_0724 (Acin_0724)
Accession : YP_004896099.1
Strain : Acidaminococcus intestini RyC-MR95
Genome accession: NC_016077
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 737584 - 739071 bp
Length : 1488 bp
Strand : +
Note : COG1012

DNA sequence :
ATGCAAAAAGTCGATCTTTTAAAAGAATATGGTCTGTACATCAACGGTGAATTTGTACCCGCCTCAGACGGAACTACGTT
TGCCGCCCATAATCCAGCCAATGGGGAAGCTTTGGCTCTGTGCGCCGAAGCCACCAAACAAGACGTGGACCGCGCCGTCA
AGGCGGCCCGTGAGGCACTCCCCAGCTGGTCCAAAACCTCTCCCATTGAGCGTCAGAACCTGCTCCTTAAGATTGCGGAC
ATCATCGATGAGAATAAGGAACGGCTGGCCCTTGTGGAGACCCTCGACAACGGCAAACCCATCCGTGAGACCATGGCCGC
TGATATTCCTTTAGGCTCGGATCACTTCCGTTATTTTGCGGGCTGCCTGCGCGCATGGGAAGGCTCTGCCACCATGCTTG
ACGACAACACCATGTCCCTTGTTCTCCATGAACCTGTAGGTGTCGTCGGTCAGGTCATCCCTTGGAACTTCCCCTTTACC
ATGGCCTGCTGGAAGCTTGCACCGGCTCTTGCTGCAGGCAATACGGTTGTCATTAAGCCGTCTTCCCATACCTCTTTGTC
CCTGCTGGAACTGCTTCGCCTCATTGACGGCGTCCTGCCCAAAGGGGTCGTGAACCTCATTACCGGCAAAGGTTCCCGCA
GCGGTCAGTGGCTCCTGGATCATCCGGACCTTGATAAGCTGGCCTTTACCGGTTCCACAGAAGTCGGTCACGGCGTCTAT
CAGGCCGCTTGTGACAAACTGATTCCTGTGACCTTGGAACTTGGCGGTAAATCGGCGAATATCGTTTTTGATGACGCTGA
CCTTAAGCAAGCCATTGACGGTACCTGCAAGGGCATCCTCTTCAATCAGGGCCAGGTCTGCTGTGCCGGTTCCCGTCTCT
TTGTCCAGGAAGGCATCTTTGATGAATTTGTCAGCCACCTGAAAGACACCTTTGAACATGTCCGGATCGGGGATCCGACA
GACCCGAATACCCAGCTGGGCGCCCAGATTTATCGTTCCCAGCAGGAAAAAGTCCTGAACTATGTCAAAATCGGCGTGGA
AGAAGGGGCAGAACTTGTGACAGGCGGCGAACGCTACACCGAAAATGGCTGTGATAAAGGCTTTTTCATGAAACCAACCA
TCCTCATCAGCCATACCAATGACTGCCGCGTCTGCCAGGAAGAAATCTTTGGCCCCGTTGTGGTCATCCAGAAATTCAAG
ACCCTTGACGAAGTGATTGACCTTGCAAACGCCAGTGAATACGGTCTAGGCGGTGCCGTCTTCACAAAGAACATCGATAC
GGCCCTCAAAGTGGCCCGTTCCGTCCGCACGGGACGGATGTGGGTCAACACCTATAACGACCTGCCCGCCGGCGCACCTT
TTGGCGGCTACAAAAAATCCGGGATTGGCCGGGAAACCCACAAAGTCCTCTTGGAACATTACAGTCAGTTGAAGAACATT
CTCATCAACCTGCGTGAAGGGGTGAGTGGGATGTATGACGTGAAATGA

Protein sequence :
MQKVDLLKEYGLYINGEFVPASDGTTFAAHNPANGEALALCAEATKQDVDRAVKAAREALPSWSKTSPIERQNLLLKIAD
IIDENKERLALVETLDNGKPIRETMAADIPLGSDHFRYFAGCLRAWEGSATMLDDNTMSLVLHEPVGVVGQVIPWNFPFT
MACWKLAPALAAGNTVVIKPSSHTSLSLLELLRLIDGVLPKGVVNLITGKGSRSGQWLLDHPDLDKLAFTGSTEVGHGVY
QAACDKLIPVTLELGGKSANIVFDDADLKQAIDGTCKGILFNQGQVCCAGSRLFVQEGIFDEFVSHLKDTFEHVRIGDPT
DPNTQLGAQIYRSQQEKVLNYVKIGVEEGAELVTGGERYTENGCDKGFFMKPTILISHTNDCRVCQEEIFGPVVVIQKFK
TLDEVIDLANASEYGLGGAVFTKNIDTALKVARSVRTGRMWVNTYNDLPAGAPFGGYKKSGIGRETHKVLLEHYSQLKNI
LINLREGVSGMYDVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-102 50
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-104 50
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-104 50
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-104 50
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-104 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acin_0724 YP_004896099.1 aldehyde dehydrogenase VFG0082 Protein 2e-102 50