Gene Information

Name : metB (Acin_2152)
Accession : YP_004897492.1
Strain : Acidaminococcus intestini RyC-MR95
Genome accession: NC_016077
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2168266 - 2169402 bp
Length : 1137 bp
Strand : +
Note : COG0626

DNA sequence :
ATGAAGTTTCAAACAACCTGTATCCATGGAGACGGGCCCAACGATGCAACGGGTGCCGTTTCACCGGCGATTTACTGTAC
GTCCACCTTTTCCCATCCTCATGTAGGAGAGTCAACAGGCTTCAACTACACCCGGGAATCCAATCCCACCCATGCCCGTT
TGGAAAAAGTCATGTCCGCCCTTGAAAGCGGCGTCGATTCCCTCGCCTTTTCGTCCGGTATGGCTGCCATTGATGCGGTG
ATGCGTCTTTTTGTATCCGGAGACCATATCCTTACAGGTTTTGATCTTTATGGCGGCTCCTTCCGTCTCTTCCGTTCCGT
CTACGAACCGTACGGTCTAACCTTTTCCGCCGTCCATACAAGCGACCTTGAAGCCGTGGAAAGAGCCATTACACCTAAAA
CAAAGGCCATCTATCTGGAAACACCGACAAATCCCACCATGGAAATCACCGACCTGCGCGCCCTGGCAGAACTTGCCCAC
AAAAAGGGTCTTCTGGTCATCGTTGACAATACGTTCCTCACCCCATATTTCCAACGCCCTCTGGAACTTGGCTGCGATAT
TGTCCTGCACAGCGGGACGAAGTACCTGGCCGGTCACAACGATATCCTCGCAGGCTTTGTAATCAGCCGGGAAAAATCCA
TCGCGGAAAAACTTCGTTCCATCTACAAAACGACAGGAGCCTGCCTGAGCGTTTTTGACGCCTGGCTCATGCTGCGCAGC
CTCCGCACCCTCCCCCTGCGTATGCGCCAGCACGAAAAAAATGCAGAAACGCTGGCTGCTTTCCTAAAGACCCAGCCCTA
TGTGCAAAAGGTCCTCTATCCAGGCCTTCCCGAACATCCGGGGTATGAGATCCAGAAAAAACAGGCCACCGGGTTTGGCG
GCATGATTTCGTTTTATGTTGATACACCGGAGCGGGCCAAGAAAATCCTTGAAGGGATTTCCCTCATCCAGTTTGCTGAA
AGTTTGGGCGGTGCCGAAAGCCTCATGACCTATCCCCGCACCCAGACTCACGCGGACTTGACGCCGGAAGAAGCAAAAGA
AAAGGGAATTACGGATACGCTTCTGCGCTTTTCCGTAGGTCTTGAAGATGTAGAAGACCTCAAGGAAGACCTTTTGTCCG
TCTTCAAAAATCTCTAA

Protein sequence :
MKFQTTCIHGDGPNDATGAVSPAIYCTSTFSHPHVGESTGFNYTRESNPTHARLEKVMSALESGVDSLAFSSGMAAIDAV
MRLFVSGDHILTGFDLYGGSFRLFRSVYEPYGLTFSAVHTSDLEAVERAITPKTKAIYLETPTNPTMEITDLRALAELAH
KKGLLVIVDNTFLTPYFQRPLELGCDIVLHSGTKYLAGHNDILAGFVISREKSIAEKLRSIYKTTGACLSVFDAWLMLRS
LRTLPLRMRQHEKNAETLAAFLKTQPYVQKVLYPGLPEHPGYEIQKKQATGFGGMISFYVDTPERAKKILEGISLIQFAE
SLGGAESLMTYPRTQTHADLTPEEAKEKGITDTLLRFSVGLEDVEDLKEDLLSVFKNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-70 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-69 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-55 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_004897492.1 cystathionine gamma-lyase BAC0207 Protein 6e-61 43