Gene Information

Name : metC (TEH_05980)
Accession : YP_004886089.1
Strain : Tetragenococcus halophilus NBRC 12172
Genome accession: NC_016052
Putative virulence/resistance : Resistance
Product : cystathionine lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.-
Position : 615153 - 616298 bp
Length : 1146 bp
Strand : +
Note : The N-terminus of this ORF was identified by Edman sequencing.; protein synonym:C-S lyase; protein synonym:L-cysteine desulfhydrase

DNA sequence :
ATGGAATTCAATACAAAATTAATACACGGTGGCACTTCAATGGATGAAACAACAGGAGGGATGTCGGTTCCTATTCATAT
GGCAACGACCTTTCAACAAAAAAAGATCGGGCAAAGTAAATATGATTACTCACGTTCGGCAAATCCGACACGTGAAGCAG
TTGAAGAGTTGATTGCTGATCTTGAAGGAGGAGCTGCTGGTCTTGCTTTTGCTTCTGGTTCAGCAGCAATTAATACGATT
TTTTCTTTGTTTTCTGCAGGTGACCATTTTGTCGTCGGTAATGATGTTTACGGTGGGACTTTTCGTTTGATTGACTCAGT
GTTAAAACGTCTCGGACTAACATTTACAGTTGTTGATACCCGTGATTTAACTGCGGTTAAACAAGCGATTACCCCTAAGA
CAAAAGCAATTTATCTTGAAACGCCTACCAATCCGCTACTTCGTGTGACTGATGTAAAAGCTGTCACAGAAATTGCGCAT
GAAAATAATCTATTAAGTATCATCGATAATACTTTTAGTTCTCCTTATATCCAGCGTCCAATTGAATTTGATGTAGATAT
TGTTATTCACAGTGCTTCTAAATACTTGGGTGGACACAGTGATGTGATTGCAGGTCTTGTGGTTACAAAAGACGCACAAT
TAGCAGAAGAGCTTCGTTTCTTGCAAAATGCGATTGGTGCTATTTTATCCCCACATGATAGCTGGCTCTTACAAAGAGGG
ATGAAAACATTAGGATTACGAATGAGAGCTCACTTACAAAATGCTGATGCTGTTTTTGACTATCTAAGTAAACAAGAAAT
GGTAGAAAAAATTTATTATCCAGGGGATCCTGAAAACGAGGACTTTACTATCGCTAAAAAACAAATGAATGGGTTTGGAG
CGATGATCTCGTTTGAATTACAAGAGGGTTTGGATCCTAGCGCATTTGTTGAACAATTACAAGTAATTACCCTAGCAGAA
AGTCTTGGTGCAGTGGAAAGTTTGATCGAAATTCCTGCTTTGATGACCCATGGTTCAATTCCGCGCGCAACTCGTATAGC
AAATGGGATAAAAGATGAACTGATTCGCCTATCTGTTGGTGTAGAAGATCCAAAAGATCTTTTAGCTGATCTTGAACAAA
GTTTTAACCATTTGAAAGGAAAATAG

Protein sequence :
MEFNTKLIHGGTSMDETTGGMSVPIHMATTFQQKKIGQSKYDYSRSANPTREAVEELIADLEGGAAGLAFASGSAAINTI
FSLFSAGDHFVVGNDVYGGTFRLIDSVLKRLGLTFTVVDTRDLTAVKQAITPKTKAIYLETPTNPLLRVTDVKAVTEIAH
ENNLLSIIDNTFSSPYIQRPIEFDVDIVIHSASKYLGGHSDVIAGLVVTKDAQLAEELRFLQNAIGAILSPHDSWLLQRG
MKTLGLRMRAHLQNADAVFDYLSKQEMVEKIYYPGDPENEDFTIAKKQMNGFGAMISFELQEGLDPSAFVEQLQVITLAE
SLGAVESLIEIPALMTHGSIPRATRIANGIKDELIRLSVGVEDPKDLLADLEQSFNHLKGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-75 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-76 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-61 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_004886089.1 cystathionine lyase BAC0207 Protein 2e-58 41