Gene Information

Name : hsdR (TEH_18970)
Accession : YP_004887388.1
Strain : Tetragenococcus halophilus NBRC 12172
Genome accession: NC_016052
Putative virulence/resistance : Unknown
Product : type I restriction-modification system restriction subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 1900162 - 1903257 bp
Length : 3096 bp
Strand : -
Note : protein synonym:type I restriction enzyme R protein

DNA sequence :
ATGTCTTTTGCGGAGGATAATTATGAAAATGCGATAATTGAGCTATTTTGCGATAAGTTAGACTACGATTATGTCCCTGG
TTGGGATGTAGATCGAGACTATAATGAACCGTTGTATTTAGACGAGTTAATGACGTCTTTAGAGCGAATTAATCCAACAC
TTTCCAGAGCGGCCATCGATGAGGCTGTGAATAAATTAAGGCGCTTTGATAATGGAACGCTAGTTCAGATAAATAAGGTG
TTTACAAGCTATCTACAGAATGGAATAGAAGTTTCTTATTATGATCGAGGCGAACAGAAGGCTAGTTTGGTTAAATTAGT
AGATTTTGAAAATATAAGCAAAAATTCATTTACAGTCATAAATCAGTGGACTATTGATGAGTATAGTAGGAAACGTCCTG
ATGTACTAGTATTTCTAAATGGTATTCCAGTAGTAGTATTTGAGCTTAAAAGCCCTTCGCGAGAAGAAACCAATGCATCG
GATGCTTATTTACAATTAAAAACTTATCAAAAGGAGATACCTAGTTTATTTAATTATAATGCTTTTTGTGTTATGAGTGA
TTTAGCAATTTCAAAAGCTGGAACTATAACTGCTGGTGAAGATCGTTTTATGGAATGGAAAACAATTGATGGTAGTTACG
AGAATACACAATATGCTCAATGGGATACTTTAATAGAGGGAATGTTTGAGAAAAAACGTTTTCTTGATATTCTTGAAAAT
TTTATTTGTTTTTCCGATGATGCAAAAATCTTAGCAGCTTATCATCAATATTTCGCTGTTCATAAAGCGGTTGTGTCTGC
TATAAAAGCAACAGAAACAGACGGACGTGGTGGTGTTTTTTGGCATACGCAGGGTAGTGGGAAGTCTTTGTCAATGGTAT
TTTTTACTCATATGATACAAAAGATTCTTAACTTACCCACAGTTGTGATATTAACTGATCGTAATGACTTAGATGAACAA
CTTTATGCGCAATTTGCTAAGTGTACTAATTTTTTAAGACAAGAACCAGTTCAAGCAAGTAATCGTGAAGAACTTAAAAA
TTTGCTTGATGGTCGCCAAGCAAATGGCATTATCTTTAGTACTATGCAAAAATTTGTAGAATCTGAGGAGCCTTTATCAG
AACGAAGAAATATAATTGTTATGGCAGATGAAGCTCATCGTGGGCAATATGGTTTGGATGAGAAAGTAGATACTAAAACA
GGTCAAATTAAATTTGGAGCAGCTCGTAGAGTACGTGATAGTTTACCTAATGCCAGCTATATTGGATTTACTGGCACGCC
AATTTCTAAAAAGGATAAATCTACTACTGAGGTTTTCGGGAACTATATTGATGTTTATGATATGACACAGGCTGTAGAAG
ATGGTGCAACTCGTCCTGTTTATTACGAAAGTCGTGTGATTCATTTAAAACTAGATAATGATGTTTTAAAACATATTGAT
GATGAGTACGATCTAATGGCAGAAAGTGCTGACAGCCAAGCAATTGAAAAAAGTAAGCAAGAATTAGGTCGTTTAGATTC
TATATTAGGCGCAGAGCAAACAATTAATGCTTTAGTCGATGATATTGTTCAACATTATGAAGAAAATCGTGAACAAGAGT
TAACAGGAAAAGCAATGGTTGTGGCTTATTCTCGTTCAATAGCGATAAAAATTTATCATAAGATGTTAGAGAAAAGACCA
AGTTGGGCTAAGACAATAGGCGTTGTAATGACTTCTAGCAATAATGATCCTGAAGAATGGCATAATATTATTGGTAATAA
AAAGCATAAAGAAGAAATGGCTAAGAAATTTAAAGATAGTGATGATGAATTTAAGATAGCCATTGTCGTTGATATGTGGT
TGACTGGATTTGATGTTCCTAGTTTAGCGACAATGTATGTTTATAAACCAATGAGTGGGCACAATTTAATGCAAGCAATT
GCTCGAGTGAATCGTGTTTACAAAGAAAAAGAGGGCGGTTTAATTGTTGATTATGTTGGAATTGCTGGTGCTTTAAAACA
GGCGATGAACGATTACACTCAAAGAGACAAAAGTAACTTTGGTGATCCTAATGTGGCTGAAACAGCTTTGCCTAAGTTTA
AAGAAAAACTAGAAGTTTGTCGTGACATCTTTCATGGTCTTGATTATTCTGCTTTTTTAGACGAAGACGCGACTAATCTT
ACCAGGGCAAAAATTATAAGTGGTGGTGTAAATTTTTTATCCAGTATTGATAAAGAAGAACAAAAAGAGGAATATCTAAA
ACAAGCTTTATTATTACGACAAGCACTACAACTTTGTCGTTCATTACTAGGAGCAAGAGAAAGGTTTGAAGCAGCATATT
TTGAAGCTGTGCGAACTGTATTAACCCGAATTAGTGGTGAGGGTGATAAATTATCGCTGAAAGAAATTAATGGACGCATT
AATAGTTTATTAAAAGCCAGTATTAAAAGTGAAGGAGTAGTTAATCTCTTTTCTGACGCTGAAACAGAGTTTTCATTATT
TGATCCACAATTTTTGGATGAAATTGCTAATATGAAGGAAAAGAACTTAGCTGTTGAACTTTTGAAAAAGTTAATTGCAG
AGCAAATTTCTCTTTATAAACAAACGAATTTAGTCAAATCTAAGAAATTTTCAGAGATGTTATCTAATTCTATGAAGGCA
TATTTGAACGGAATGTTGACAAATGAAGAAGTAATTCAAGAATTAAAAGATATGGCGAAAGATATGAAAAATGCTACTGA
AGAAGGAACTGATTTAGGTTTAACTGATGAAGAACTGGCATTTTATGACGCTATTACTAAACCGGAAGCTGTTGAGGATT
TCATTGAAAACGATCAGTTAGTATCATTGACTCATGAACTTACTGATATGTTACGAAAAAGCCGTACAGTTGATTGGCAA
AAGAAAGAATCAGCACGTGCTCATATGCGTCGTAAAGTAAAAAAACTTTTGCGTAAATATAAATATCCACCAGAAGGTAT
GGAAGAAGCAATTTCAACAGTAACTCAGCAATGTGAGTTGTGGGTAGATATTGGAAGCTATTATTATGATAGTGCCAGAG
AAGTAAATGGACTACCAATGGTGGCAGACAAAGACGAAAACTTTAGAGTTAGATAA

Protein sequence :
MSFAEDNYENAIIELFCDKLDYDYVPGWDVDRDYNEPLYLDELMTSLERINPTLSRAAIDEAVNKLRRFDNGTLVQINKV
FTSYLQNGIEVSYYDRGEQKASLVKLVDFENISKNSFTVINQWTIDEYSRKRPDVLVFLNGIPVVVFELKSPSREETNAS
DAYLQLKTYQKEIPSLFNYNAFCVMSDLAISKAGTITAGEDRFMEWKTIDGSYENTQYAQWDTLIEGMFEKKRFLDILEN
FICFSDDAKILAAYHQYFAVHKAVVSAIKATETDGRGGVFWHTQGSGKSLSMVFFTHMIQKILNLPTVVILTDRNDLDEQ
LYAQFAKCTNFLRQEPVQASNREELKNLLDGRQANGIIFSTMQKFVESEEPLSERRNIIVMADEAHRGQYGLDEKVDTKT
GQIKFGAARRVRDSLPNASYIGFTGTPISKKDKSTTEVFGNYIDVYDMTQAVEDGATRPVYYESRVIHLKLDNDVLKHID
DEYDLMAESADSQAIEKSKQELGRLDSILGAEQTINALVDDIVQHYEENREQELTGKAMVVAYSRSIAIKIYHKMLEKRP
SWAKTIGVVMTSSNNDPEEWHNIIGNKKHKEEMAKKFKDSDDEFKIAIVVDMWLTGFDVPSLATMYVYKPMSGHNLMQAI
ARVNRVYKEKEGGLIVDYVGIAGALKQAMNDYTQRDKSNFGDPNVAETALPKFKEKLEVCRDIFHGLDYSAFLDEDATNL
TRAKIISGGVNFLSSIDKEEQKEEYLKQALLLRQALQLCRSLLGARERFEAAYFEAVRTVLTRISGEGDKLSLKEINGRI
NSLLKASIKSEGVVNLFSDAETEFSLFDPQFLDEIANMKEKNLAVELLKKLIAEQISLYKQTNLVKSKKFSEMLSNSMKA
YLNGMLTNEEVIQELKDMAKDMKNATEEGTDLGLTDEELAFYDAITKPEAVEDFIENDQLVSLTHELTDMLRKSRTVDWQ
KKESARAHMRRKVKKLLRKYKYPPEGMEEAISTVTQQCELWVDIGSYYYDSAREVNGLPMVADKDENFRVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 3e-177 42
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 9e-175 42
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 3e-176 42