Gene Information

Name : yrhB (GYO_2965)
Accession : YP_004878201.1
Strain : Bacillus subtilis TU-B-10
Genome accession: NC_016047
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2733790 - 2734929 bp
Length : 1140 bp
Strand : -
Note : -

DNA sequence :
ATGAAGAAAAAAACATTGATGATTCATGGGGGAATCACAGGTGATGAGAAAACAGGCGCAGTGTCCGTGCCTATTTATCA
AGTAAGCACGTACAAGCAGCCGAAAGCAGGGCAGCATACCGGCTATGAGTATTCAAGAACGGCCAATCCGACAAGGTCCG
CTCTCGAAGCACTTGTGACAGAGCTGGAAGGCGGGGAAGCAGGCTATGCGTTCAGTTCTGGAATGGCTGCTATTACAGCG
GTTATGATGCTGTTTAACAGCGGAGATCATGTCGTGTTGACTGATGATGTGTATGGCGGAACATACCGCGTGATGACAAA
GGTACTTAATCGTCTTGGCATTGAATCAACATTTGTCGATACAAGCAGCAGAGAAGAAGTTGAAAAAGCGATTCGCCCAA
ACACAAAAGCCATTTATATTGAGACACCGACAAACCCGCTGCTCAAAATCACCGACTTGGCGCTCATGGCTGATATCGCA
AAAAAAGCGGGTGTTCTGCTTATCGTCGACAATACCTTTAACACTCCTTATTTTCAGCAGCCGCTTACTTTAGGAGCTGA
TATCGTGCTTCACAGTGCGACAAAATATCTTGGCGGACACAGTGACGTCGTCGGCGGTTTAGTTGTGACAGCTTCGAAAG
AGCTTGGAGAAGAGCTGCATTTTGTGCAAAACTCCACAGGCGGCGTCCTTGGCCCTCAAGATTCCTGGCTGTTAATGAGA
GGAATCAAAACATTGGGACTCAGAATGGAAGCGATCGATCAAAATGCGCGGAAAATCGCAAGTTTTCTGGAGAATCATCC
TGGTGTCCAAACGTTATATTATCCTGGTTCTTCAAATCATCCCGGACATGAGCTCGCAAAAACACAAGGGTCTGGCTTCG
GTGGCATGATCTCCTTTGATATCGGCAGTGAAGAGCGGGTTGATGCATTTTTAGGGAATCTGAAACTGTTTACCATTGCT
GAAAGCCTGGGCGCGGTAGAAAGCTTAATTTCTGTTCCGGCAAGAATGACACATGCCTCTATTCCGAGAGAGCGCAGGCT
TGAATTAGGCATTACGGACGGATTGATTAGAATTTCTGTAGGAATTGAAGATGCGGAGGATTTGCTGGAAGATATTGAGC
AGGCGCTTGAAAATATATAA

Protein sequence :
MKKKTLMIHGGITGDEKTGAVSVPIYQVSTYKQPKAGQHTGYEYSRTANPTRSALEALVTELEGGEAGYAFSSGMAAITA
VMMLFNSGDHVVLTDDVYGGTYRVMTKVLNRLGIESTFVDTSSREEVEKAIRPNTKAIYIETPTNPLLKITDLALMADIA
KKAGVLLIVDNTFNTPYFQQPLTLGADIVLHSATKYLGGHSDVVGGLVVTASKELGEELHFVQNSTGGVLGPQDSWLLMR
GIKTLGLRMEAIDQNARKIASFLENHPGVQTLYYPGSSNHPGHELAKTQGSGFGGMISFDIGSEERVDAFLGNLKLFTIA
ESLGAVESLISVPARMTHASIPRERRLELGITDGLIRISVGIEDAEDLLEDIEQALENI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-103 59
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-101 58
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-73 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yrhB YP_004878201.1 cystathionine gamma-synthase BAC0207 Protein 2e-64 44