Gene Information

Name : Bcoa_0274 (Bcoa_0274)
Accession : YP_004858278.1
Strain : Bacillus coagulans 36D1
Genome accession: NC_016023
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 273604 - 274593 bp
Length : 990 bp
Strand : -
Note : PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; KEGG: erh:ERH_0070 D-lactate dehydrogenase

DNA sequence :
ATGAGAAAAGTTGTTGCCTATGAGACGCGGGCGGATGAATTCCCCTTATTTCAGAAATTCGCGAGAAAATTTGATTTGGA
TATCAAGTATGTGGATGATGTGTTAACCCCTGAAACGGCAATGAAAGCAATGGGGGCTGAAGCGGTGACGATCCTTGGGA
ATTATCCGGTGGGCGCCGAAACTTTTATGGCTTTAAGAGATGCCGGTGTAAAATATATTGGCTTGAGGACTGCAGGGTAT
AATCATATCGATCAGGAAGCCGCCAAAGCATATGGCATTCGTTTTTCGAATGTGGCGTATTCGCCCTATTGTGTTGCCGA
TTTTGCAACGATGCTGATTTTGATGTGTGTAAGGAAAGCAAAACAGATCTTAAGCCGTGTGGAGACACAAGATTTTTCTG
TGGAAGGGATTCAGGGCAGGGAAATGCATAACTTAACGATCGGGATTATTGGCGCCGGCAGAATCGGCAGTATTGTTGCG
AAAAATTTGTCCGGTTTTGGCTGCAACATCATTGCACACGATACCGTTGAAAGAGATGAATTGCGCGGCATTTTGAAATA
TGTATCTTTGGATGAACTGCTGAAGGAAAGCGATGTGATAACCATCCACACACCCTTATTTGATCGTACATACCATATGA
TTAACCAGGATCGGATTGCAAAAATGAAGGACGGCGTTTGCATCATCAATTGTTCCCGTGGTGCCGTAGTGGATACGGAT
GCGCTTATCGCAGGGATCGAGGCGGGGAAAGTCGGCGCTGCCGGGATTGATGTACTGGAAGATGAGGAAGGGATTTTTCA
TTATGACCGCCGCACGGATATTTTGGCCCACCACCAGCTGGCTATTCTGAGATCTTTTCCCAATGTGATCGTCACGCCGC
ACACTGCGTTTTACACCGATCAGGCGGTTAGCGATATGGTGGAAATGGCGCTAACATCGCTTGTATCCTTTATGGAGACG
GGGAAGAGCAGGTGGGAGATAAAATCATGA

Protein sequence :
MRKVVAYETRADEFPLFQKFARKFDLDIKYVDDVLTPETAMKAMGAEAVTILGNYPVGAETFMALRDAGVKYIGLRTAGY
NHIDQEAAKAYGIRFSNVAYSPYCVADFATMLILMCVRKAKQILSRVETQDFSVEGIQGREMHNLTIGIIGAGRIGSIVA
KNLSGFGCNIIAHDTVERDELRGILKYVSLDELLKESDVITIHTPLFDRTYHMINQDRIAKMKDGVCIINCSRGAVVDTD
ALIAGIEAGKVGAAGIDVLEDEEGIFHYDRRTDILAHHQLAILRSFPNVIVTPHTAFYTDQAVSDMVEMALTSLVSFMET
GKSRWEIKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 7e-51 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcoa_0274 YP_004858278.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein AF310956.2.orf4.gene Protein 3e-51 42
Bcoa_0274 YP_004858278.1 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein AF155139.2.orf4.gene Protein 3e-52 41