Gene Information

Name : Bcoa_1787 (Bcoa_1787)
Accession : YP_004859762.1
Strain : Bacillus coagulans 36D1
Genome accession: NC_016023
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1939973 - 1942108 bp
Length : 2136 bp
Strand : +
Note : KEGG: sag:SAG1257 cation transporter E1-E2 family ATPase; TIGRFAM: ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; ATPase, P-type, heavy metal translocating; PFAM: ATPase, P-type, ATPase-as

DNA sequence :
ATGTCTAATCAACAAACCTTACCATCTGAACAAGAAATGAAAACCTATCGCGTTCAAGGATTATCTTGTACAAATTGTGC
AGCCAAATTTGAAAATAACGTGAAAAATTTAGAAGGTGTAAAGGACGCAAAAGTAAATTTTGGAGCATCCAAAATTACAG
TTTATGGTGAAACAACGATTGAAGAATTAGAAAAAGCAGGGGCCTTTGAGAATTTAAAGATTCAGGATGAAAAAGAACAA
AGGATAGAGTATAAGCCTTTTTGGAAGGAAAAAGAAAATATTAAGGTTTATATTTCGGCTGCATTGCTCATTATTAGTTG
GTTTCTAGGAAGGCAATTTGGTGAAAATAATATTATCCCTACGATTGGATATGCTGCATCGATTTTAATAGGTGGATATT
CCTTATTTATTGAAGGCCTTAGAAATTTAAGTAAATTTAAATTCGATATGGATACGCTCATGACGATCGCCATAATAGGA
GCCGCGTTGATTGGACAATGGGGTGAAGGAGCAACCGTTGTGATCCTTTTCGCCATTAGCGAAGCCTTAGAGCGTTATTC
AATGGATAAAGCTCGTCAATCGATTGGAATGTTGATGGATATCGCTCCAAAAGAAGCGTTAATTCGCCGTGAAAATGAAG
AAATAATGGTTCACGTGGAGGATATTCAAATCGGTGATATTATGATCGTCAAGCCTGGGCAAAAATTAGCGATGGACGGA
ATAGTTATAAAGGGTACATCCACATTAAATGAGGCTGCTATCACTGGAGAAAGTGTTCCAGTAACCAAAACCATTGATGA
TGAGGTCTATGCTGGCACATTAAATGAAGAAGGATTATTAGAAGTAAAAGTAACCAAACGGGTTGAAGATAACACATTAT
CGAAAATTATTCATTTAGTAGAAGAAGCTCAAGCAGAGAAAGCACCTTCTCAAGCATTTGTTGATAAATTTGCAAAATAT
TACACACCAGCTATCATCATTTTGGCTACATTAATTGCGATTATTCCACCGTTATTATTCGGAGGAGATTGGAGTTACTG
GATATATGAAGGATTAGCTGTATTAGTGGTTGGTTGCCCTTGTGCCTTAGTTGTTTCAACTCCAGTTGCAGTAGTTACTG
CCATAGGAAATGCGGCAAGAAACGGTGTTTTAATTAAAGGTGGGATTCATTTAGAAGAAGCAGGTCACTTAAAGGTTATT
GCTTTTGATAAAACAGGTACACTTACAAAAGGTATTCCAGCGGTTACAGATATTGTGACATTTGGTGGAAATGAAAATGA
GTTGATGACGATTACAGCTGCCATCGAAAAGGGTTCCCAGCATCCACTTGGTACAGCCATTATAAGAAAAGCAGAAGAAA
ATGGATTGAATATTAATGGAGTTTCGGTTGAAGAGTTTCAATCCATTACAGGTAAAGGCGTAAAAGCGAAAGTAAATAAT
GAAATGTATTATGTAGGAAGTTCAACTCTTTTTGAAGAATTGCACGGTAGTATCGAAAACGATAAAAAACAAAAAATTGA
AAAGATGCAAACACAAGGGAAAACGGTGATAGTGTTAGGAACGGAAAAAGAAATTCTTTCGTTTATTGCTGTTGCTGATG
AAATAAGAGAATCATCGAAATCCGTGATCCGTAAACTTCATCAAATTGGAATTGAAAAAACTGTTATGCTTACAGGTGAT
AACAAAAGAACAGCAGAAGTCGTCGGAAAAGAAGTAGGTGTTTCTGATATTAAGGCCGATTTGCTACCAGAAGATAAATT
AAATTTCATTAAAGAACTTCGAGGGAAAAATCAAGGTGTCGCAATGGTCGGTGATGGTGTGAACGATGCACCTGCTCTTG
CAGCTTCAACTGTTGGTGTTGCGATGGGAGGAGCTGGAACCGATACAGCATTAGAAACAGCTGATATTGCGTTAATGTCT
GATGATTTAAGTAAATTGCCATATACCATCAAATTAAGTCGTAAGGCTTTATCTATCATCAAACAAAACATTACATTCTC
TTTAGCAATTAAATTAGTAGCATTGTTGTTAGTAATCCCCGGTTGGTTAACGCTTTGGATAGCGATATTTTCCGATATGG
GAGCAACATTACTTGTAACGCTAAACAGTTTAAGGTTATTGAAGGTTAAAGAATGA

Protein sequence :
MSNQQTLPSEQEMKTYRVQGLSCTNCAAKFENNVKNLEGVKDAKVNFGASKITVYGETTIEELEKAGAFENLKIQDEKEQ
RIEYKPFWKEKENIKVYISAALLIISWFLGRQFGENNIIPTIGYAASILIGGYSLFIEGLRNLSKFKFDMDTLMTIAIIG
AALIGQWGEGATVVILFAISEALERYSMDKARQSIGMLMDIAPKEALIRRENEEIMVHVEDIQIGDIMIVKPGQKLAMDG
IVIKGTSTLNEAAITGESVPVTKTIDDEVYAGTLNEEGLLEVKVTKRVEDNTLSKIIHLVEEAQAEKAPSQAFVDKFAKY
YTPAIIILATLIAIIPPLLFGGDWSYWIYEGLAVLVVGCPCALVVSTPVAVVTAIGNAARNGVLIKGGIHLEEAGHLKVI
AFDKTGTLTKGIPAVTDIVTFGGNENELMTITAAIEKGSQHPLGTAIIRKAEENGLNINGVSVEEFQSITGKGVKAKVNN
EMYYVGSSTLFEELHGSIENDKKQKIEKMQTQGKTVIVLGTEKEILSFIAVADEIRESSKSVIRKLHQIGIEKTVMLTGD
NKRTAEVVGKEVGVSDIKADLLPEDKLNFIKELRGKNQGVAMVGDGVNDAPALAASTVGVAMGGAGTDTALETADIALMS
DDLSKLPYTIKLSRKALSIIKQNITFSLAIKLVALLLVIPGWLTLWIAIFSDMGATLLVTLNSLRLLKVKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 65
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 63
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcoa_1787 YP_004859762.1 cadmium-translocating P-type ATPase BAC0298 Protein 3e-112 46
Bcoa_1787 YP_004859762.1 cadmium-translocating P-type ATPase BAC0092 Protein 1e-95 42
Bcoa_1787 YP_004859762.1 cadmium-translocating P-type ATPase BAC0124 Protein 2e-91 41