Gene Information

Name : Bcoa_1194 (Bcoa_1194)
Accession : YP_004859188.1
Strain : Bacillus coagulans 36D1
Genome accession: NC_016023
Putative virulence/resistance : Virulence
Product : ATPase AAA
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1283842 - 1286292 bp
Length : 2451 bp
Strand : -
Note : KEGG: afl:Aflv_0077 class III stress response-related ATPase, ClpC; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; UvrB/UvrC protein; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGATGTTTGGAAGATTTACAGAGAGAGCCCAGAAAGTGCTGGCCCTTTCCCAGGAAGAAGCAATCCGCCTGAAACATAA
CAATATCGGAACGGAACATATTTTGCTCGGACTTGTCCGCGAAGGGGAAGGCATCGCGGCAAAAGCGCTGTACGGCCTGG
GTTTAAGCGCCGAAAAAATCCAGGAAGAAGTGGAAACCCTGATCGGGAACGGCCAGGAAATTTCCCAAACGATCCACTAC
ACGCCAAGGGCCAAAAAAGTGATTGAACTGTCAATGGATGAAGCGAGAAAACTCGGGCACTCCTATGTTGGAACGGAACA
TATCCTCCTCGGGCTGATCCGTGAAGGTGAAGGCGTGGCGGCACGCGTGCTGACAAATCTCGGCGTTAGCTTAAATAAAG
CAAGGCAACAGGTGCTCCAATTATTGGGCAACAGTGAAGCGTCCGTACAGGGCGGTTCGGCGGCCAGCGTCAGCACACCG
ACACTGGACAGTCTGGCCCGCGATTTAACAGCGATCGCACGGGAAGATTCCCTTGATCCTGTAATCGGGCGCAGCAAAGA
AATTCAACGCGTCATTGAAGTACTGAGCCGGAGGACAAAAAACAACCCTGTCCTTATCGGGGAACCGGGCGTTGGGAAAA
CGGCCATTGCAGAAGGCCTTGCCCAGCAAATTGTGCATAATGAAGTGCCGGAAACGCTGCGTGACAAACGGGTTATGACG
CTTGATATGGGTACGGTTGTGGCCGGTACAAAATACCGTGGCGAATTTGAAGACCGCCTGAAAAAAGTCATGGATGAAAT
CCGCCAGGCCGGTAATATCATTCTTTTCATCGATGAATTGCATACCTTAATTGGGGCCGGCGGTGCGGAAGGAGCCATTG
ATGCTTCCAATATTTTAAAACCGTCGCTTGCCCGCGGCGAACTGCAGTGCATCGGGGCAACAACACTGGATGAATACCGG
AAATATATTGAAAAAGATGCTGCACTGGAAAGAAGGTTCCAGCCGATCCAGGTCGATGAGCCGACGATTGATGAGTCGAT
CCAGATTTTAAAAGGGCTGCGCGATCGCTATGAAGCACACCATCGCGTCTCGATTACCGATGAGGCGATCGAAGCCGCTG
TAAAACTTTCGGACCGCTATATCGCAGACCGGTTCCTGCCGGATAAAGCGATTGACTTAATCGATGAAGCCGGATCGAAA
GTGCGTCTTCGTTCCTTTACAACGCCGCCGAATTTGAAAGAACTGGAATTGAAACTGGAAGAGGTACGCAAGGAAAAAGA
TGCGGCCGTCCAGAGCCAGGAATTTGAAAAAGCGGCTGCGTTAAGGGATACCGAACAGAAACTGCGCGAACAGCTGGAGG
AAACGAAGAAAAACTGGAAGGCAAAACAAGGACAGGAAAACAGTGAAGTCACAGTCGATGATATTGCGCTTGTTGTTTCG
AGCTGGACGGGAGTTCCGGTGACGAAACTGGCACAAACCGAAACGGAAAGGCTTCTGCACCTTGAAGAGATCCTTCACTC
CCGAGTGATCGGGCAGGAAGAAGCGGTACTTGCAGTGGCGAAAGCAGTCCGCCGTGCACGGGCAGGGTTAAAAGATCCGA
AACGCCCGATCGGTTCCTTCATTTTCCTCGGGCCGACAGGGGTCGGAAAAACAGAACTGGCGCGGGCGCTTGCGGAAGCG
ATGTTCGGCGATGAGGATGCCATGATCCGGATCGACATGTCCGAATACATGGAGAAACATTCGACTTCCCGCCTCGTAGG
TTCGCCGCCTGGATATGTCGGTTTTGAAGAAGGCGGGCAGCTGACGGAAAAGGTACGGAGAAAACCGTATTCGGTTGTGC
TGCTTGATGAAATTGAAAAAGCGCACCCGGATGTGTTCAACATTTTGCTCCAGGTACTGGATGACGGCCGGCTGACCGAT
TCCAAGGGCCGCACGGTTGATTTTAGCAATACGATTGTCATCATGACATCGAATGTCGGCGCAGATGCTTTAAAACGCAA
CAAGAGCGTCGGCTTCACCATTCAGGATACCGTCGAGGCCGATTATAAAGACATGAAGGACAAAGTGCTCGAGGAACTGA
AAAAAGCGTTCCGGCCTGAGTTTTTGAACCGTGTTGATGAAACCATTGTGTTCCATTCGCTCGAGAAGAAACAGTTGAAC
GAAATTGTCACGTTGATGGCGAAAGAATTGTCGGACCGGTTAAAAGAGCATCATATCGAACTTGTGCTGACGGATGCCGC
AAAAGAAAAAGTGGCGGAAAAAGGCTACGATCCGGAATACGGCGCGCGGCCGCTGCGCAGATCGATTCAGAAAAACATCG
AAGACCGCCTTTCGGAAGAAATGCTGAAAGGCAATATAAAAGAAGGGCAAAAGGTATTGGTCGATGTAAAAGACGGCGAA
TTTACTTTTGCCAGTGTGGCAGAGTCGGAAGCTGTATCGTCCAATTCTTAA

Protein sequence :
MMFGRFTERAQKVLALSQEEAIRLKHNNIGTEHILLGLVREGEGIAAKALYGLGLSAEKIQEEVETLIGNGQEISQTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLTNLGVSLNKARQQVLQLLGNSEASVQGGSAASVSTP
TLDSLARDLTAIAREDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVHNEVPETLRDKRVMT
LDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEYR
KYIEKDAALERRFQPIQVDEPTIDESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYIADRFLPDKAIDLIDEAGSK
VRLRSFTTPPNLKELELKLEEVRKEKDAAVQSQEFEKAAALRDTEQKLREQLEETKKNWKAKQGQENSEVTVDDIALVVS
SWTGVPVTKLAQTETERLLHLEEILHSRVIGQEEAVLAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAEA
MFGDEDAMIRIDMSEYMEKHSTSRLVGSPPGYVGFEEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTD
SKGRTVDFSNTIVIMTSNVGADALKRNKSVGFTIQDTVEADYKDMKDKVLEELKKAFRPEFLNRVDETIVFHSLEKKQLN
EIVTLMAKELSDRLKEHHIELVLTDAAKEKVAEKGYDPEYGARPLRRSIQKNIEDRLSEEMLKGNIKEGQKVLVDVKDGE
FTFASVAESEAVSSNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 4e-93 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcoa_1194 YP_004859188.1 ATPase AAA VFG0079 Protein 0.0 80
Bcoa_1194 YP_004859188.1 ATPase AAA VFG0080 Protein 4e-147 53