Gene Information

Name : clpC (RATSFB_1246)
Accession : YP_004857734.1
Strain : Candidatus Arthromitus sp. SFB-rat-Yit
Genome accession: NC_016012
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1414595 - 1417033 bp
Length : 2439 bp
Strand : -
Note : -

DNA sequence :
ATGTTTGAAAAATTAACTGAAAGGGCTAGAAAGGTTATAAGCTATTCGGGTGATGATGCACTAAAGTTGGGTCATGGATT
TATAGGAACAGAACATATATTACTTGGTTTACTAAGAGAGGATGGACCTGCACAGAAAATTTTAAATTCTTTTGATGTAT
ATTATGATGATATATTTAAGGAAATTAGAACTATTTTATCTCCAGGAGAGATAGAAATAAAAAATAGTGAGATACCATTA
ACACCTAGGACTAAAAAGGTTATAGAGAGCAGTATAGATGAGGCTAAGAAATTAGGGCATAATCATGTATCTCCTGAACA
TATACTACTATCTATTATAAATGAAACTGACGGAGTTGCTTATAAGATACTAGATAAAAAAGGTGTGTCCATAGTAAAAA
TATGGAACCAAACTATAAATGCCCTTAATGTTACAATTGATATACAAAATCCACACGAAAAAGAACAACAACTTAAAAAT
TTACCGACACCTGTATTGGATCAGCATGGCAGAGATCTTACAAAATTGGCTAATGAAGGGAAATTAGATCCTGTTATAGG
AAGAGATATAGAAACACAAAGAGTTCTTGAAATATTGTGTAGAAGAATAAAAAATAATCCATGTTTAATAGGTGATCCGG
GAGTTGGTAAAACAGCTATTATCGAGGGGTTAGCACAAAAAATAACAGAAGGTAATATACCGGAGATATTGAAAAATAAA
CGTGTTGTGACCTTAGATTTATCTTCTTTGATTGCTGGAACAAAATACAGAGGAGAATTTGAGGAAAGATTAAAGAAAAT
AATGGAAGAGATAAAAAAATCCAAAAATATAATTTTGTTTATAGATGAGATACATACAATAATTGGTGCTGGTGGAGCCG
AGGGAGCTATAGATGCATCTAATATATTAAAACCAGCCTTAGCTAGAGGAGAAATACAGTGTATAGGAGCCACAACTATT
GATGAATATAGAAAATATATAGAAAAAGATACGGCTTTAGAACGAAGATTTCAACCCATATTTGTTGGAGAACCTAATGA
GGATGAAACGATAGATATATTAATGGGTATAAGAGATAAATATGAAACTCATCATAAAGTAAAAATTACTGATGAAGCTA
TAAGGTTTGCGGTTAGTCTATCTGTTAGATTTATCCCAGATAGATATTTACCAGATAAAGCTATAGATTTAATTGATGAG
GCTGCTGCAAAAATAAGGGTTAGAAATTTAACAGTACCTATTGAAGTTAAAGAAATAGAAGAGGAAATAGCAAAAGTTGG
TAAGGAAAAGCAAGAAGCGATAACTTTAGAAGATTTTGAGAAGGCAGCTTCGCTTAGGGATAAAGAACAGAAACTTAAAG
AAAGATTGGAAAATTCAAAAGAGAAGTGGAAAGTTGAAAAATATGACAAGGAATTTATACTTACTGAGCAGGAGTTAGCG
TCTGTTGTAGCAAGCTGGACTAAGATACCAGTTGAAAAATTAACACAAACAGAATCGGAAAAATTATTAAAATTAGAGGA
AATGTTAAAAAATAGAGTAATAGATCAAAATGAGGCTGTAACATCTGTTGCTAAGGCTGTTAAACGTGGACGTGTTGGAA
TTAAGGATCCTAAAAGACCTATTGGTTCATTTATATTTTTAGGGCCTACTGGAGTTGGTAAAACTGAATTGTGTAAGGCT
CTATCAGATATTGTTTTTGGAAGTGAAGAGAATATAATAAGATTTGATATGTCTGAATTTATGGAAAAACATACGGTATC
AAAGATTATTGGATCACCACCAGGGTATATTGGATTCCAAGAGGGGGGACAATTGACAGAGAAAGTCAGGAGATCACCAT
ATTCTATTATATTATTTGATGAAATAGAGAAGGCTCATCCGGATATATTTAATATAATGCTACAAATTTTAGAAGATGGA
CATTTAACAGATTCAAATGGGAAGAGAGTTAGTTTTAAAAATACAATAATAATATTAACGTCAAACATAGGAGCAGATAT
AATTAATAAAAATTCATCATTAGGTTTTATAAATCACAAGAATAATGAAGAAGAAATTTATACTAAAATGAAAAATAATG
TTTTGAGTGAGCTTAAGAAAAATTTTAGACCTGAGTTTTTAAATAGATTAGATGATGTGATAGTATTTAAACCGCTGGAT
AAAAAAAGTCTCACAAAAATATTAGATAAGATGCTACTTGATTTTAATATTAGAGTGTCAAGTCAAGATATATCAATTAA
TTTTAGTGAAGATGTAAAGAATTATATACTTGATAATAGTTTGAGTGAAAAATATGGGGCTAGGCCATTAAGAAGGTCTA
TAACTAAATATATTGAGGATACTTTGTCTGACCAAATATTATTAGGAAACATTAAATCTGGAGATAATGTGGAAGCTGTG
TTAAAAGACAATGAAATTTTTTATTTTAAGAAGCCTTAA

Protein sequence :
MFEKLTERARKVISYSGDDALKLGHGFIGTEHILLGLLREDGPAQKILNSFDVYYDDIFKEIRTILSPGEIEIKNSEIPL
TPRTKKVIESSIDEAKKLGHNHVSPEHILLSIINETDGVAYKILDKKGVSIVKIWNQTINALNVTIDIQNPHEKEQQLKN
LPTPVLDQHGRDLTKLANEGKLDPVIGRDIETQRVLEILCRRIKNNPCLIGDPGVGKTAIIEGLAQKITEGNIPEILKNK
RVVTLDLSSLIAGTKYRGEFEERLKKIMEEIKKSKNIILFIDEIHTIIGAGGAEGAIDASNILKPALARGEIQCIGATTI
DEYRKYIEKDTALERRFQPIFVGEPNEDETIDILMGIRDKYETHHKVKITDEAIRFAVSLSVRFIPDRYLPDKAIDLIDE
AAAKIRVRNLTVPIEVKEIEEEIAKVGKEKQEAITLEDFEKAASLRDKEQKLKERLENSKEKWKVEKYDKEFILTEQELA
SVVASWTKIPVEKLTQTESEKLLKLEEMLKNRVIDQNEAVTSVAKAVKRGRVGIKDPKRPIGSFIFLGPTGVGKTELCKA
LSDIVFGSEENIIRFDMSEFMEKHTVSKIIGSPPGYIGFQEGGQLTEKVRRSPYSIILFDEIEKAHPDIFNIMLQILEDG
HLTDSNGKRVSFKNTIIILTSNIGADIINKNSSLGFINHKNNEEEIYTKMKNNVLSELKKNFRPEFLNRLDDVIVFKPLD
KKSLTKILDKMLLDFNIRVSSQDISINFSEDVKNYILDNSLSEKYGARPLRRSITKYIEDTLSDQILLGNIKSGDNVEAV
LKDNEIFYFKKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004857734.1 negative regulator of genetic competence ClpC/mecB VFG0079 Protein 0.0 55
clpC YP_004857734.1 negative regulator of genetic competence ClpC/mecB VFG0080 Protein 3e-138 52