Gene Information

Name : NH8B_2057 (NH8B_2057)
Accession : YP_004847286.1
Strain : Pseudogulbenkiania sp. NH8B
Genome accession: NC_016002
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2149555 - 2151864 bp
Length : 2310 bp
Strand : +
Note : -

DNA sequence :
ATGGCCGGCTGCTGCGACCACGACCCCAAAAACAAACCCGACCCCTTGGAGCGGCATGTCGTCCCGGCTCGACGCCATGC
GGGCCCGAAGTATCGTGTGGCTCCGATGGCAGCGCAAAGCCATCGGCACGACCACGCTCACGACCATGCCGATGGCCAGT
GCTGCGCGCCCGCCGCGATCGCCTTTGGCGCGCTCGCCGCGCCGGAAACGGTCGCAAACGGCATGCGGACCGCCATGCGC
ATCATGCAGATGGACTGCCCCACAGAAGAGGCGCTGATTCGCCGGAAACTGGGCACGATGGCGTCCGTCAAGAGCCTGGA
GTTCAACCTGATGCAGCGGGTGCTGACGGTGGTGCATGCCCCCGATGCGCTGGCCCCGATCCTGGAGGCGGTGCGCTCTC
TCGGCTTCGAGCCCGAAGTCCCGGATGCCCAAGGCCAGCTTGCAAAGCCGGTGGCGCAGAAGAAACCGTGGTGGCCTTTG
GCTCTTGCCGGCACGGCGGCCATCGCCTCGGAGGCGGCGGGGTGGGGCGGTTTGCCGGGCACCCTGTCCGCCGCACTGGC
CATTCTCGCTGTCGCTTCATGCGGGCTGACCACCTACAAGAAGGGATGGGTGGCGATTCGCCACCGCAACCTGAACATCA
ACGCTCTCATGAGCATCGCCGTGACCGGCGCACTGTTGTTGGGGCAGTGGCCCGAGGCGGCCATGGTGATGGTGCTGTTC
ACGCTCGCCGAACTGATCGAGGCCAAGTCGCTCGACCGGGCCCGTCATGCGATTAAGGGGCTGATGGAACTGGCGCCGGA
GGTGGCGACCAGTTTGCAAGCCGACGGGACGTGGCAGGAGGTCGAGGCCAGGACGGTGACGGTGGGCAGCCTGGTCCGGG
TCCGGCCCGGCGAGCGTATCGGGCTCGATGGCGAGATCGTGCGCGGTCGCTCCAGCATCAACCAGGCACCGATCACGGGT
GAGAGCATGCCGGTCGACAAGGGCGAGGGCGACGCCGTGTTTGCCGGCACCATCAACCAGTCGGGTTCCTTCGAGTACCG
CGTCACGTCTGTAGCGGCCGATACCACGCTGGCGCGCATCATTCATGCCGTCGAACAAGCACAAGGCTCAAAAGCACCGA
CGCAGCGCTTTGTCGACCAGTTCGCCCGCGTCTACACCCCGGCCGTGTTCGCCATTGCCCTGGCCGTGGCCGTGCTGCCA
CCCTGGCTGCTGGGCGGCAACTGGCACGACTGGATCTACAAGGCGCTGGTCTTGCTGGTGATCGCCTGCCCGTGCGCGCT
GGTGATCTCCACCCCTGTCACCATCGTCAGCGGCCTGGCCGCCGCGGCGCGCCATGGCATTCTGATCAAGGGCGGCATCT
ATCTGGAGCAAGGCCGCCTGCTGAAATGGCTGGCGCTCGACAAGACCGGCACCATTACCCATGGCCAACCGCAACAAACC
GACTTCGAGCTACACGCTGACGTCGCAGCGGAACACTGCCGCCGCCTGGCGGCCAGCCTGGCCGGCCGTTCTGATCACCC
CGTATCGCAAGCCATCGCCAACCAAGCCGAACAGGACGGTGCCAAACGGGACAATGTCGCCGCTTTCGAGGCGCTACCGG
GGCGCGGCGTACGCGGTATGATCGCCGGCAAGCGCTACTTTCTCGGCAATCATCGCCTGGTGCATGAACTCGATCGGTGC
ACTCCTTCGCTGGAAGCGCGTCTCGATGAGCTGGAACGCCAGGGCAAAAGCGTCGTCATGCTCATCGACGAACACCAGGT
CCTGGCCTTGTTCGCCGTGGCCGACACGGTCAAGAGCTCCAGTCGCGACGCCATCGCCGAACTGCACGCATTAGGAGTCA
AGACGGTCATGCTGACCGGCGACAACCCACATACGGCAGCAGCGATAGCGAAGCAAGTGGGCATCGACCAGGTTCGCGGT
AACCAGATGCCCGAAGACAAGCTGAAAGCCGTCGAATCCTTCGAAAAAGCAGGTCCGGTGGGGATGGTGGGGGATGGCAT
CAACGACGCCCCGGCACTGGCTCGTGCCCACATTGGCTTTGCCATGGGCGCGATGGGCACCGACACGGCGATCGAAACCG
CTGACGTTGCCTTGATGGATGACGACTTGCGCAAGATTCCGACCTTTATCCGCCTGTCGCGCGCCACTCGCTCCGTACTG
CTCCAGAACATTACCCTGGCGCTGGGGATCAAGGGGCTATTCCTGGCGCTGACCTTGGGCGGCCTGGGGACGATGTGGAT
GGCGGTGTTCGCCGACGTGGGTGCGAGCCTGCTGGTGGTCGGGAATGGCTTGAGGCTGCTGCGACAGTAG

Protein sequence :
MAGCCDHDPKNKPDPLERHVVPARRHAGPKYRVAPMAAQSHRHDHAHDHADGQCCAPAAIAFGALAAPETVANGMRTAMR
IMQMDCPTEEALIRRKLGTMASVKSLEFNLMQRVLTVVHAPDALAPILEAVRSLGFEPEVPDAQGQLAKPVAQKKPWWPL
ALAGTAAIASEAAGWGGLPGTLSAALAILAVASCGLTTYKKGWVAIRHRNLNINALMSIAVTGALLLGQWPEAAMVMVLF
TLAELIEAKSLDRARHAIKGLMELAPEVATSLQADGTWQEVEARTVTVGSLVRVRPGERIGLDGEIVRGRSSINQAPITG
ESMPVDKGEGDAVFAGTINQSGSFEYRVTSVAADTTLARIIHAVEQAQGSKAPTQRFVDQFARVYTPAVFAIALAVAVLP
PWLLGGNWHDWIYKALVLLVIACPCALVISTPVTIVSGLAAAARHGILIKGGIYLEQGRLLKWLALDKTGTITHGQPQQT
DFELHADVAAEHCRRLAASLAGRSDHPVSQAIANQAEQDGAKRDNVAAFEALPGRGVRGMIAGKRYFLGNHRLVHELDRC
TPSLEARLDELERQGKSVVMLIDEHQVLALFAVADTVKSSSRDAIAELHALGVKTVMLTGDNPHTAAAIAKQVGIDQVRG
NQMPEDKLKAVESFEKAGPVGMVGDGINDAPALARAHIGFAMGAMGTDTAIETADVALMDDDLRKIPTFIRLSRATRSVL
LQNITLALGIKGLFLALTLGGLGTMWMAVFADVGASLLVVGNGLRLLRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-112 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-112 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 4e-113 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NH8B_2057 YP_004847286.1 heavy metal translocating P-type ATPase BAC0298 Protein 0.0 69
NH8B_2057 YP_004847286.1 heavy metal translocating P-type ATPase BAC0461 Protein 5e-83 43
NH8B_2057 YP_004847286.1 heavy metal translocating P-type ATPase BAC0455 Protein 1e-86 41