Gene Information

Name : pyk (LSA_07670)
Accession : YP_004841112.1
Strain : Lactobacillus sanfranciscensis TMW 1.1304
Genome accession: NC_015978
Putative virulence/resistance : Virulence
Product : Pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 743402 - 745162 bp
Length : 1761 bp
Strand : -
Note : -

DNA sequence :
ATGAAGAGAACAAAAATCGTAAGTACACTTGGACCCGCTGCTAATGATGTTGATACTATTTCAGCATTATTAAACTCAGG
TGCCAATGTTTTTCGTTTCAACTTTTCACATGGAGATCATGAAGAACATTTGTCACGTATGAATATGGTAAAGGAAGCTG
AAAAGAAAACTGGTAAGCTCGCTGGTATTTTACTTGATACTAAAGGTGCTGAAATCAGAACTACTAAAGAAGTAGATGGT
GAAATCCAATTCAAGATTGGTGATAAGTTCAGAATTTCTATGGACGACACACTTGAAGGTACTAAGGAAAAAATTGCCGT
TACTTACCCAGGCTTATACGATGATGTTAAAGTTGGCGGACACGTATTATTCGATGATGGTTTAGTTGATGCTAAGGTTA
TCGATAAGGACGCTAAGAACCGCGAATTAGTTTGTGAAATTATGAATGATGGTGTACTTGGTTCACGTAAAGGTGTTAAC
GCACCTGGTGTATCAATTAACTTGCCAGGAATCACTGAAAAAGATTCAGATGATATTCGTTTTGGTTGTGAACATGGAAT
TAGCTTTATTTCTGCTTCATTTGTTCGTAAACCTCAAGATATTTTAGATATTCGTGCCTTATTAGAAGAAAAGAACATGA
CTGATGTTCAAGTATTTCCTAAGATTGAATCACAAGAAGGTATTGATAACTTTGCTGAAATCTTAAAAGTTTCAGATGGT
TTAATGGTTGCTCGTGGTGACATGGGTGTTGAAATTCCACCAGAAAATGTTCCAACTGTTCAAAAACGTCTTATCAAGAT
GTGTAATGAAGTTGGTAAACCAGTTATTACTGCTACTCAAATGTTAGATTCAATGCAAGAAGAACCTCGTCCAACTCGTG
CCGAAGTATCTGATGTTGCTAATGCTGTTTATGATGGTACTGATGCAACTATGCTTTCTGGTGAAAGTGCCCACGGTGAC
TATCCAGTTGAATCAGTTGCTATGATGGCTCGTATTGATAAAGTTGCTGATGATCATTTCCAAGAATTTGGTACTCCACG
TCCTGTATTTAATGACAGTGATGTTACTGAAGCTCTTGGCGAATCAGTTGCACGTATTGCTAAAGACATGGATATTCACA
CTATTGTTTGTGCTACTGGATCAGGTTATACTGCACGTATGATTTCGAAATATCATCCAAATGCTAATATTTTAGCTCTT
ACTTTTGATGATCGTGTACGTCGTGGTTTGACTGTTAACTATGCTGTTAACCCAGTACTTGTAAACAAACCAGAAACAGC
AGATGAAATGGTTGAACTTGCTACAGCTAAAGCAGTTGAAACTGGTTTAGCTAAAGAAGGCGAACAAATCATCATTCTTA
CTGGTGTTCCTTTGGGTGATGAAGGTACTACTAACACAGTTCGTGTTCAATTAATTGGTACTAAATTAGCTCAAGGTCAA
GGTATTGGTGACCAAGTTGTTATTGGTAAAACAGTTGTAGCTGATGACGCAAAATCAGCTAACGATAATACTGTTGATGG
TAGCGTGTTAGTTGTTAAAGATACTAACAAAGCTTACTTACCAGCTATGAAGAAAGCTAGCGCAATCGTTGTTGAAGAAG
GTGGTTTAACTTCATATGCAGCAGTTATTGGAATTTCATTGAATATTCCAGTAATCGTTGCCGCAAACGATGCTACTAAG
AACATTAAAAACGGTGCTTCAGTTACTGTTGATGCTCGTCGTGGTATGGTTTATGCAGGTAACCAATCAAAAAACGCTTA
A

Protein sequence :
MKRTKIVSTLGPAANDVDTISALLNSGANVFRFNFSHGDHEEHLSRMNMVKEAEKKTGKLAGILLDTKGAEIRTTKEVDG
EIQFKIGDKFRISMDDTLEGTKEKIAVTYPGLYDDVKVGGHVLFDDGLVDAKVIDKDAKNRELVCEIMNDGVLGSRKGVN
APGVSINLPGITEKDSDDIRFGCEHGISFISASFVRKPQDILDIRALLEEKNMTDVQVFPKIESQEGIDNFAEILKVSDG
LMVARGDMGVEIPPENVPTVQKRLIKMCNEVGKPVITATQMLDSMQEEPRPTRAEVSDVANAVYDGTDATMLSGESAHGD
YPVESVAMMARIDKVADDHFQEFGTPRPVFNDSDVTEALGESVARIAKDMDIHTIVCATGSGYTARMISKYHPNANILAL
TFDDRVRRGLTVNYAVNPVLVNKPETADEMVELATAKAVETGLAKEGEQIIILTGVPLGDEGTTNTVRVQLIGTKLAQGQ
GIGDQVVIGKTVVADDAKSANDNTVDGSVLVVKDTNKAYLPAMKKASAIVVEEGGLTSYAAVIGISLNIPVIVAANDATK
NIKNGASVTVDARRGMVYAGNQSKNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-94 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-95 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-95 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-94 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_004841112.1 Pyruvate kinase VFG0479 Protein 2e-95 46