Gene Information

Name : guaA (LSA_01810)
Accession : YP_004840582.1
Strain : Lactobacillus sanfranciscensis TMW 1.1304
Genome accession: NC_015978
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 177514 - 179163 bp
Length : 1650 bp
Strand : -
Note : -

DNA sequence :
TTGTCAGAATTACTGGTGCCGGTTTACGTGAATCACATCCACATGATGTTATCATTACTAAGGATGCCCCTAACTACAAA
AAATAGGAGAATAATTATGGTAAAAAATGAACGTAATTACGACTCTGTAATGGTCCTTGACTTTGGTAGTCAATACAACC
AATTAATTACTCGTCGTGTTCGTGAAATGGGAGTTTATTCAGAACTTAAACCCCACACAATGACCGCTAAAGAAATTAAA
GCGATGAATCCAAAGGCCATCATCTTTTCTGGTGGTCCTAATAGTGTTAATGGTGACGGCGCTCTAGCCGTTGATCCTGA
AATCTTTAATCTTGGTCTTCCTATCTTAGGAATTTGTTACGGAATGCAATTAATGGCCAAAGACCTTAAAGGTGGCGAAA
TTGTTACTGCCGATAACAGTGAATATGGCCAAGCTCAAATTGAAGTAACTGACAAAGATTCTAAGTTCTTCAAGGGCATG
AACGACAAACAAACTGTTCTAATGAGTCACGGTGACTTTGTTACCAAAGTTCCCGATGGTTTTGAGATAACAGCAACTAG
TGGCTCATGCCCTATCTCAGCCATGGCTGATCCAAAACGTGGCTTTTACGCCGTTCAATTCCATCCTGAAGTTAACTTAA
CTGAAGAAGGACGCGAAATGTTACACCACTTTGTCTTTGACATTGCTGGTGCTGAAGCCAACTGGTCAATGGATGACTTC
ATTGAAGATGCCATTGCCAACATTAAAGAAACCGTTGGTGATAAAAAAGTACTCCTCGGTCTTTCTGGTGGAGTTGACTC
ATCAGTAGTTGCGGTGCTTTTACACCGTGCCATTGGTGACCAACTTATCTCAGTTTTCGTTGACCACGGTTTATTACGGA
AAAACGAAGCTCAACAAGTGCTTAAAGCTCTAGGTGACGATTTCGGTTTAAACATTGATTTCGTTGATGCCAGTGAACTC
TTCTTAGGTAAACTAAAGGGTGTAACTGATCCCGAAACCAAACGGAAAATCATCGGAAAAGAATTTATCGATACCTTCTC
AACCGAAGCTCGTAAATTTGACGATGTTGATTTCTTAGCTCAAGGAACTCTTTATACTGATGTCATTGAATCTGGGACTG
ATACAGCTCAAACTATCAAGTCTCACCATAACGTTGGTGGTCTTCCTGATGACTTGAAATTCAAGTTAATCGAACCTTTG
AACAAATTGTTCAAAGATGAAGTTCGGGAACTTGGTGAAAAACTAGGGATGCCTAAAGCATTAGTTTGGCGTCAACCTTT
CCCAGGTCCTGGTTTAGCAATCCGAATCATTGGTGAAGTTACTCCAGAACGTTTACGCATGGTACGTGATTCTGATGCCA
TCTTACGTGATGAATTTGCTAAAGCTGGTTTGAACAAGACTGTTTGGCAATACTTCACTGCCCTTCCTGGAATTAAGAGT
GTTGGAGTTATGGGTGACGAACGGACTTATGACGAAGCCGTTAACATTCGTGCCGTAACCTCCGTTGATGGAATGACTGC
TGAATTTGCGGAAGTTCCTTGGGAAGTTTTAGGTAAGGTTTCTAAACGAATTGTTGATGAAGTAGCGGGAGTTAACCGTG
TACTTTACGACATTACGGGTAAGCCACCTGCAACAATTGAATATGAATAA

Protein sequence :
MSELLVPVYVNHIHMMLSLLRMPLTTKNRRIIMVKNERNYDSVMVLDFGSQYNQLITRRVREMGVYSELKPHTMTAKEIK
AMNPKAIIFSGGPNSVNGDGALAVDPEIFNLGLPILGICYGMQLMAKDLKGGEIVTADNSEYGQAQIEVTDKDSKFFKGM
NDKQTVLMSHGDFVTKVPDGFEITATSGSCPISAMADPKRGFYAVQFHPEVNLTEEGREMLHHFVFDIAGAEANWSMDDF
IEDAIANIKETVGDKKVLLGLSGGVDSSVVAVLLHRAIGDQLISVFVDHGLLRKNEAQQVLKALGDDFGLNIDFVDASEL
FLGKLKGVTDPETKRKIIGKEFIDTFSTEARKFDDVDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPDDLKFKLIEPL
NKLFKDEVRELGEKLGMPKALVWRQPFPGPGLAIRIIGEVTPERLRMVRDSDAILRDEFAKAGLNKTVWQYFTALPGIKS
VGVMGDERTYDEAVNIRAVTSVDGMTAEFAEVPWEVLGKVSKRIVDEVAGVNRVLYDITGKPPATIEYE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-159 62
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-159 62
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-159 62
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-122 50