Gene Information

Name : clpC (LSA_11430)
Accession : YP_004841463.1
Strain : Lactobacillus sanfranciscensis TMW 1.1304
Genome accession: NC_015978
Putative virulence/resistance : Virulence
Product : Negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1103294 - 1105771 bp
Length : 2478 bp
Strand : -
Note : -

DNA sequence :
CTGAAAGAAGGCTATTTAATGGAAGACTCATTAACACCTAGTGCAAAAAAAACACTTATGATTGCGCAAGAACAAGCACG
TGGTTTTCAACATCAATCGGTTGGAACTGAGCATTTATTATTGGCATTATCCATTGAAAAAAGTGGAATCGCTTACCAAA
CCTTAAATCAACTTTCTGTTACTGAACAGGATGTTAAAGAAGAAATTGAACAAATTGCCGGTTATGGTAATTTACAAAAC
GACGGAACAACTTATTTGCCATATTCTCCTAAGATGCGTGACATTTTAAATTTAGCTGGTCAAATTGCTAAACAATATGG
CAGCAAACGGGTTGGAACGGAACATTTGTTATTAGCGTTAACTAGCGAAAACGAAATCGTTTCATCAAGAATTCTTAACA
GCTTAGGAATTTCTCCTGAAGATGTTCGTAAGATTACGATTCGGAAAATGGGGGTTCCTGATCAAGGAATACCAACTGAA
TCTAAGAATGATGATAAAGAAAAAACACCAACGCTTGATTCATTTGCAAAAGATCTTACCAAAGCAGCTCGAGATGGCCA
ACTAGATCCAATTATTGGGCGTGATCAAGAAGTTCGTCGTGCAATTCAAATTTTAAGTCGGCGGACGAAAAATAATCCAG
TTCTAATCGGAGAGCCTGGGGTTGGTAAAACAGCAATTGCAGAAGGACTAGCTCAAAAAATTGTGGAAAAGAAAGTTCCT
CAAGATATGACCAATAAACGTGTTATGGCCCTTGATATGGGAAGCCTAGTTGCAGGGACTAAATATCGTGGGGAATTTGA
AAACCGACTTAAAAAAATTATTAATGAAATCAAAAGTAACGGACACGTTATTTTATTTGTTGATGAATTGCATACTTTAA
TTGGAGCTGGAGGAGCAGAAGGTGCCATTGATGCTTCTAATATTTTAAAGCCAACTTTAGCTCGTGGTGAAATTCAGATG
ATTGGGGCAACGACCTTAAATGAATACCAAAAGCATATTGAAGCTGATGCTGCTTTAGAACGTCGTTTTGCCACGGTACA
AATTGAAGAACCTAGTGTCGATGAAGCAAAGAAAATTTTGGCTGGTTTACGACCAAAATACGAAGAATATCATCATGTGA
AAATCACCGATGATGCGATTAATGCAGCTGTGGATTTATCAAGTCGTTACATTAGTGGTCGCTTTTTACCTGATAAAGCC
ATTGACTTGATGGATGAAGCTGCTGCTAAAGTTCGAATTGATGCAATGGGAGATTCTACTGAATTAGTTAAGCAACAACG
TGAACTTGATGAAGCAAGGTCGAATAAAGATCGTGCCATTGAAGAACAACGTTTTGACGATGCTGTAACTTTTCGTAGTC
AAGAACAACAACTGGAAAAATCGGTTGCTGCTCTAATGGAAAAAGACAAAAAGAAACGTGAACATGAAAATAAGCAACAT
AACTATAAACTCAAAGAAAACTCAGAGTCAGTTGCGCAAATTGTTGCTGAATGGACAGGCATTCCAGTTACGCACCTTAA
GAAAACGGATGCAGATCGATTGGTTAACTTGGAAAATGTATTGCATAAACGGGTGATTGGGCAAGATGAGGCGGTTACTG
CAGTTGCTAAAGCAGTAAGAAGAGCTCGAAGTGGATTGAAAGATCCTAATCGTCCAATTGGCTCATTTATTTTCCTTGGA
CCTACTGGTGTGGGAAAAACGGAATTAGCTAAGGATTTAGCAGAAGAAATGTTTGGCTCAGAAGACGATGTAATTAGAGT
CGATATGAGTGAGTACATGGAAAAATATTCTACTAGTCGTTTAGTTGGATCTGCTCCAGGATATGTTGGTTATGAAGAAG
GAGGTCAACTAACTGAAAAAGTTAGAAAACATCCTTACTCCGTTGTTTTGCTTGATGAAGTGGAAAAAGCACATCCAGAT
GTCTTTAACTTGCTCTTACAAGTTCTTGATGACGGATTTCTAACTGATTCTAAAGGTCGTAAAGTTGACTTTAAAAATAC
AATTATCATTATGACATCTAATTTAGGTGCCACAGCGTTACGTGAACAAAAAACAGTTGGTTTTGATGCCAACCGTTCAG
AAAACAACGATGCTGAAGTTAAACGAGTAATTCAAGAAAAGATGAAACAATTCTTCCGTCCTGAATTCTTAAACCGAGTT
GATGAAACAGTTATTTTCCATAGTTTAACCGAATCAGAACTTCATCGAATTGTTAAATTGATGACCAAACGTTTAGTAGA
TCGGGTTGAAAAACAAGGGTACATTTTAAAAATCACTCCTGCAGCCATTGATGCGGTTGCTAAAAAAGGTTACAACCCAG
AATACGGAGCTCGTCCTTTAAGAAGAGCACTTCAAAGTGAAATCGAAGATCCTTTAAGTGATGCATTGTTAGCTGGTAAA
TTTAAACCAGGTGATAAAATCACAATTGGAGCACAAAAAGGTAAAATTACGCTTACACATAAAACTCCAGTTATATAG

Protein sequence :
MKEGYLMEDSLTPSAKKTLMIAQEQARGFQHQSVGTEHLLLALSIEKSGIAYQTLNQLSVTEQDVKEEIEQIAGYGNLQN
DGTTYLPYSPKMRDILNLAGQIAKQYGSKRVGTEHLLLALTSENEIVSSRILNSLGISPEDVRKITIRKMGVPDQGIPTE
SKNDDKEKTPTLDSFAKDLTKAARDGQLDPIIGRDQEVRRAIQILSRRTKNNPVLIGEPGVGKTAIAEGLAQKIVEKKVP
QDMTNKRVMALDMGSLVAGTKYRGEFENRLKKIINEIKSNGHVILFVDELHTLIGAGGAEGAIDASNILKPTLARGEIQM
IGATTLNEYQKHIEADAALERRFATVQIEEPSVDEAKKILAGLRPKYEEYHHVKITDDAINAAVDLSSRYISGRFLPDKA
IDLMDEAAAKVRIDAMGDSTELVKQQRELDEARSNKDRAIEEQRFDDAVTFRSQEQQLEKSVAALMEKDKKKREHENKQH
NYKLKENSESVAQIVAEWTGIPVTHLKKTDADRLVNLENVLHKRVIGQDEAVTAVAKAVRRARSGLKDPNRPIGSFIFLG
PTGVGKTELAKDLAEEMFGSEDDVIRVDMSEYMEKYSTSRLVGSAPGYVGYEEGGQLTEKVRKHPYSVVLLDEVEKAHPD
VFNLLLQVLDDGFLTDSKGRKVDFKNTIIIMTSNLGATALREQKTVGFDANRSENNDAEVKRVIQEKMKQFFRPEFLNRV
DETVIFHSLTESELHRIVKLMTKRLVDRVEKQGYILKITPAAIDAVAKKGYNPEYGARPLRRALQSEIEDPLSDALLAGK
FKPGDKITIGAQKGKITLTHKTPVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004841463.1 Negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 55
clpC YP_004841463.1 Negative regulator of genetic competence clpC/mecB VFG0080 Protein 2e-143 50