Gene Information

Name : RHOM_04780 (RHOM_04780)
Accession : YP_004838008.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Virulence
Product : ATPase AAA-2
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1030354 - 1032807 bp
Length : 2454 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGCAGACAGCATATACAGCAAAGGCAAAAAAGGCGATTGATATTGCAACGCGGATATCAAAGTCATTGCATCACAGTTA
TATCGGCACGGAGCACATACTGCTTGGCCTGTTGAAAGAGGGAACTGGTGTGGCAAGCCAGGTACTTGCCGACAATGGTG
TAGAGTATGATAAGGTGCTGGAACTGATCGAGGAGCTGATTGCACCGGGGAATGCGGTTGCGGTTCTGGAGGACGGATTG
TCCCCGAGAGCGGCGCATGTGCTTGAGGTATCCAAAGCGGAGGCGGCGCGTTTCCACTCGGAGAAGATTGGAACAGAACA
CCTTTTAATTGCGATGATCAAGGAGACGGAATGTGTGGCGTCCAGACTGTTGAATACATTGTCTGTCAATGTGCAGAAAA
TGTATGTGGACACCCTGATCGCGATGGGCGAGGATGTAAGCCAGTATAAGGATGAATTCCAGAACGGAAAACCCGGAAAG
CGGAGAAATGCGGAGGGAACGCCGGCGCTGGATCAGTTTTCCAGAGATCTGACAGAACTTGCGCGCGCCGGAAAGCTCGA
TCCGGTGGTCGGCAGAGAGACGGAGATCGACCGCGTCATCCAGATTTTAAGCCGGAGAAGCAAGAACAATCCGTGCCTGA
TCGGAGAACCCGGCGTAGGAAAAACGGCGATTGTAGAGGGAATCGCAGAGCGCATTGCGGGCGGAATGGTTCCAGATACG
GTGCTTGGAAAAAGAGTGGTTTCCCTGGATCTTTCCGGGATTGTGGCAGGCTCAAAGTACAGAGGTGAATTTGAGGAGCG
CATCAAGAAGGTGCTGGCAGAGGTGGCGAAAGCTGGAAACGTCCTGCTGTTCATTGATGAGATTCATACCATCATCGGGG
CGGGCGGAGCGGAAGGCGCGATTGATGCATCCAACATTTTAAAACCTGCACTTGCGAGAGGCGAGGTGCAGGTGATCGGC
GCGACGACCATCGAAGAGTACCGCAAATATATCGAAAAAGATGCAGCTTTGGAGCGGCGTTTCCAGCCAGTCGTTGTGGA
GGAGCCGACGGAGGAAGAAGCCATTTCCATATTAAAGGGACTGCGTGGGCAGTATGAGAGCCACCACCATGTGACGATTA
CGGATGAGGCCGTGGAGGCGGCAGTGCGTCTTTCCGCGCGTTACATCAACGATCGATTCCTCCCGGACAAGGCGATTGAC
CTGATGGATGAGGCTGCGGCAAAAGTGCGCCTTCATGTGGGCGGAGACCCCAAGGAGGCTGCAGAACTCCGGCGGGAGAT
TGCGGAGTTGCAGGAGACATTGGAGGAAGCACTTTCCGGCGGAGACCTGGAAACGGCGAGGGAGTCGCAGGCAAAACGCC
AGGAACTGGAAGAAAAGTTGGAAAAACTGAATACAAAGGCAAAACAGGGCGGCAGACGGCATCACCAGACCGTCGGAGAG
GACGAGATTGCCGATGTGGTGTCGGGATGGACGAAAATCCCGGTGAAGAAGCTTACAGAGGGGGAGGCTGCCAGACTCAA
AAAACTGGAGGCAACCCTTCACAAGCGCGTGATCGGACAGGAGGAAGCGGTATCAGCTGTGGCGAAAGCCGTGCGGAGAG
GACGCGTCGGATTAAAAGATCCCAAGCGTCCGATCGGCTCGTTCCTTTTTCTGGGACCGACCGGCGTCGGCAAGACCGAG
ATATCCAAGGCACTGGCGGAAGCTGTCTTTGGACAGGAGCAGGCAATGATCCGCATCGATATGTCTGAGTACATGGAGAA
ACACAGCGTGTCGAAAATGATCGGTTCGCCGCCTGGATATGTCGGACATGAGGACGGCGGACAGCTGAGTGAGAAAGTGC
GGAGAAATCCATACGCCGTGATTCTGTTTGACGAGATAGAGAAGGCACATCCGGATGTGTTTAATATTCTGCTGCAGGTG
CTTGACGACGGACATATCACAGATTCCCAGGGAAGAAAAGTGGACTTTAAGAATACCATCATCATTATGACCTCCAACGC
GGGAGCGCAGGCGATTGTGGAGCCGAAGAAGCTTGGCTTTGCTTCCGGCAATGACGAGAAGCAGAACTATGAGCGGATGA
AGGGCAGCGTGATGGAGGAGGTCCGCAGAATTTTCAAACCGGAATTCCTAAACCGTATTGACGAGACCATTGTATTCAGG
GCGCTGAATAAGGACGACATGAAACAGATCGTAGGTCTGATGACAAAAGAACTGGCGAAGCGCTGTGAAACACAACTTGG
CATTACACTTGTCGTGCGCGATGCCGCAAAGCAGTACATTGTGGATAAGGCGTATGACCCGAAGTATGGAGCCAGACCGC
TGCGGCGCAAGATTCAGGATGAGATTGAGGATCCGCTTGCGGAAAAACTTCTCGACGGAAGCATCCGGCGGGGTGACGAA
GTGATCGTCACGACGAAGAAAAATGCAATTTTTCTGGAGTCCAAGAAAAAGTAA

Protein sequence :
MQTAYTAKAKKAIDIATRISKSLHHSYIGTEHILLGLLKEGTGVASQVLADNGVEYDKVLELIEELIAPGNAVAVLEDGL
SPRAAHVLEVSKAEAARFHSEKIGTEHLLIAMIKETECVASRLLNTLSVNVQKMYVDTLIAMGEDVSQYKDEFQNGKPGK
RRNAEGTPALDQFSRDLTELARAGKLDPVVGRETEIDRVIQILSRRSKNNPCLIGEPGVGKTAIVEGIAERIAGGMVPDT
VLGKRVVSLDLSGIVAGSKYRGEFEERIKKVLAEVAKAGNVLLFIDEIHTIIGAGGAEGAIDASNILKPALARGEVQVIG
ATTIEEYRKYIEKDAALERRFQPVVVEEPTEEEAISILKGLRGQYESHHHVTITDEAVEAAVRLSARYINDRFLPDKAID
LMDEAAAKVRLHVGGDPKEAAELRREIAELQETLEEALSGGDLETARESQAKRQELEEKLEKLNTKAKQGGRRHHQTVGE
DEIADVVSGWTKIPVKKLTEGEAARLKKLEATLHKRVIGQEEAVSAVAKAVRRGRVGLKDPKRPIGSFLFLGPTGVGKTE
ISKALAEAVFGQEQAMIRIDMSEYMEKHSVSKMIGSPPGYVGHEDGGQLSEKVRRNPYAVILFDEIEKAHPDVFNILLQV
LDDGHITDSQGRKVDFKNTIIIMTSNAGAQAIVEPKKLGFASGNDEKQNYERMKGSVMEEVRRIFKPEFLNRIDETIVFR
ALNKDDMKQIVGLMTKELAKRCETQLGITLVVRDAAKQYIVDKAYDPKYGARPLRRKIQDEIEDPLAEKLLDGSIRRGDE
VIVTTKKNAIFLESKKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 7e-179 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHOM_04780 YP_004838008.1 ATPase AAA-2 VFG0079 Protein 0.0 55
RHOM_04780 YP_004838008.1 ATPase AAA-2 VFG0080 Protein 5e-145 52