Gene Information

Name : RHOM_03315 (RHOM_03315)
Accession : YP_004837717.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 715770 - 717548 bp
Length : 1779 bp
Strand : +
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGTTAAGAAAGACAAAAATTGTATGTACGTTAGGACCGTCGACGGATGATGAGAATGTGATGCGCAGCCTGATCGAGGA
AGGCATGAATGTGGCGCGCTTTAACTTTTCACATGGAGGACACGAGGAGCAGTTTGGAAGACTTACGATGCTTCGCAAGC
TGCGAGAGGAAATGAAGCGTCCGGTGGCGGCTCTACTGGATACAAAGGGGCCGGAGATCCGTCTGAAAGAGTTCGCAAGC
GGCAAGGTGGAGCTGAAGAACGGACAGACATTTACTCTGACGACGGAGGATATCGTGGGCGATGAGAGCCGTGTGGCGAT
CACGTACAAGGATCTGCCGGACGATGTGAAGCCGGGAGATACCATTCTGATCGATGACGGACTGATCGGTCTGGAAGTCA
AGAAGATCCAGAAAGTATCGGGCACAAAGGCGGATGCAGAGGGCAAAATGCCGATGGATATTGTCTGTACCGTTATGAAC
GGCGGTATGGTTTCCAATAAAAAGGGCGTGAATGTTCCGAACGTGGAGCTTTCCATGCCGTACATCAGCGAGAAAGACTA
CGGCGATATTGTATTTGCGGTGGAGAACGACTATGATTTCATTGCGGCATCCTTCGTGCGCTGCGCGGATGACGTGCTTG
CAATCCGCAAGATTCTTGAGGAAAAAGGCGGCGAGGACATTCATATCATCGCGAAGATCGAGAACATGCAGGGTGTGCAG
AACATCGATGAGATCATCCGCGTCTCCGACGGTATCATGGTTGCCCGTGGCGACATGGGTGTAGAGATTCCGCTTGAGGA
CGTTCCTGTCATTCAGAAGATGATTATCAAGAAAGTCAGCGGTGCCGGAAAAGTGGTTATCACGGCGACCCAGATGTTGG
ATTCCATGATGAAACATCCGCGTCCGACCCGCGCGGAGGCGACAGACGTTGCCAACGCAATCTATGACGGAACAAGTGCG
ATCATGCTTTCCGGTGAGACGGCTGCCGGCCAGTATCCGATCGAGGCATTGAAGACGATGGTCCGCATTGCGGTTCGCAC
CGAGTGCGATATCAACTATCTGCAGCGTTTCAAGGACCGTAAGAATATGAGCAGCCCGGATGTGACGAACGCGATTTCCC
ATGCAACCTGTACGATGGCGGGAGACCTCAATGCGGCGGCGATTCTGGCAGTATCCAAGTCCGGACGCACAGCGCGCATG
ATCTCCAAGTACCGCCCGTACTCTCCGATCATCGGCGCGTGCCTGACGGAGAAAGTATACCGTCAGCTCGGACTTTCCTG
GGGCGTTGCACCGCTGCTTCTTGAGCAGAAGAATAAGGCGGAAGAACTGTTTGACTATGCGGTTGACACTGCAGAGACGG
CAGGTCTGATCAGCAAGGGCGATGTGGTTGTTCTGACTGCCGGCGTACCGCTTGGCGTATCCGGAACGACCAACCTCATC
AAGGTGCAGGTGGCAGGACATATCCTGGTAAAAGGAAAAGGAATTGCAGGTAAGAAGATTGCAGCAAACCTGTGCGTCTG
CCACAGCGAGGAAGATCTTGCGAACTTCAAAGAGGGAGACATCATCGTTGCTGCAGATACCAACAACTGCATGATGAAGC
AGATGCGTCAGGCATCCGGTCTCATCGTGGAGGCGGACAGCGACAGCTGCCATGCAGCGATTGCAGGACTCAGCCTGGAT
ATTCCGGTACTGATCGGCGCGAAGAACGCACTGGAGGTATTAAAGTCCAGCGCTTATGTAGAGCTTGACAGCGAAAACGG
AGTTGTGACAGCGATCTAA

Protein sequence :
MLRKTKIVCTLGPSTDDENVMRSLIEEGMNVARFNFSHGGHEEQFGRLTMLRKLREEMKRPVAALLDTKGPEIRLKEFAS
GKVELKNGQTFTLTTEDIVGDESRVAITYKDLPDDVKPGDTILIDDGLIGLEVKKIQKVSGTKADAEGKMPMDIVCTVMN
GGMVSNKKGVNVPNVELSMPYISEKDYGDIVFAVENDYDFIAASFVRCADDVLAIRKILEEKGGEDIHIIAKIENMQGVQ
NIDEIIRVSDGIMVARGDMGVEIPLEDVPVIQKMIIKKVSGAGKVVITATQMLDSMMKHPRPTRAEATDVANAIYDGTSA
IMLSGETAAGQYPIEALKTMVRIAVRTECDINYLQRFKDRKNMSSPDVTNAISHATCTMAGDLNAAAILAVSKSGRTARM
ISKYRPYSPIIGACLTEKVYRQLGLSWGVAPLLLEQKNKAEELFDYAVDTAETAGLISKGDVVVLTAGVPLGVSGTTNLI
KVQVAGHILVKGKGIAGKKIAANLCVCHSEEDLANFKEGDIIVAADTNNCMMKQMRQASGLIVEADSDSCHAAIAGLSLD
IPVLIGAKNALEVLKSSAYVELDSENGVVTAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-92 47
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-92 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-91 47
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-92 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHOM_03315 YP_004837717.1 pyruvate kinase VFG0479 Protein 1e-92 47