Gene Information

Name : RHOM_01890 (RHOM_01890)
Accession : YP_004837432.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 414481 - 416589 bp
Length : 2109 bp
Strand : +
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGGCTCAACATAAATTGGTAATTGCCGAAAAACCATCAGTTGCCCAGAGTTTGGCGGCTGTGATCGGTGCAACCGTCCG
TAAGGACGGGTATCTGGAGGGCAACGGCTGGCGTGTCAGCTGGTGCGTGGGCCACCTGGCCGGTCTTGCGGATGCAGACA
GCTATGACCCAAAGTATGCCAAGTGGCGATATGATGATCTGCCTATCCTGCCGGAACATTGGCAGATGGTGGTGGGAAAA
GATAAGAAAAAGCAGTTTGATATTCTCAAAAAGCTGATGAATGCCCCGGATGTGACGGAAGTGGTAAATGCCTGTGATGC
CGGACGCGAGGGCGAGATGATCTTCCGTAGCGTCTATGAGCTGGCAGGTTGCAAGAAGCCGATGAAAAGGCTCTGGATTT
CTTCGATGGAGGACTCCGCCATAAGGAAAGGCTTTGCAAACCTGCGCCCCGGTGCGGACTATGACGGACTTCGGGATGCT
GCCCTCTGCCGTGCCAAGGCCGACTGGCTGGTGGGGATCAATGCGACAAGGCTTTTTTCCGTGCTGTATCACCGAACCCT
CAACATCGGGCGCGTGATGTCCCCGACGCTGGCGCTTATTGTTCAGCGAGAAGCTGAGATCGACACCTTTAAGCCGATTC
CCTTTTATACCGTGGCGCTGGAGCTGCCCGGTCTTACCGTATCCGGGGAGCGCATGGCGGATAAGGCTGCTGCTGAGCAG
CTGAAAGAAGCCTGTCAGGGTGTAAATGTCACAATCAAAAAGGTGGAGTGCAAGGAAAAGTCCGAAAAGCCGCCTGCCCT
CTATGACCTGACTACTCTGCAAAGAGATGCCAACCGCCTGCTTGGATTTACAGCCCAGCAGACCCTGGACTATCTGCAAA
GCCTGTATGAAAAAAAGCTCTGCACCTATCCCCGTACTGACAGCCGCTATCTGACTGGCGATATGGCAGACAGCCTGCCG
GTGCTGGTCAATCTGGTTGCCAATGCTATGCCGTTTCGCAAAGGAATCGCCATTACCTGTGATCCGCAGACGGTAATCAA
CGATAAGAAAGTAACCGACCACCACGCAGTAATCCCTACCAGAAATCTCAAGGATGCAGACCTTTCTGCCCTTCCTGCGG
GAGAAAAAGCGGTGCTGGAGCTGGTGGCCCTGCGTCTGATGTGCGCCGTAGCCCAGCCCCATATCTATTCGGAAACCGTT
GTGATTGCAGCGTGTGCCGGTGGGGAGTTTACCACAAAAGGAAAAACAGTGAAGCATCCCGGATGGAAAGCACTGGAGGA
CGCTTATCGTGCCAAAATGAAGGATACAGAGCCGAAAAAAGAGGGCGTAGAGAAAGCCCTGCCGGAGCTGACCGAAGGAC
AGACACTTTCGGTTTCTGCGGCAATCGTCAAAGAAGGCAAAAGCAGTCTGCCTCAGCACTTTACGGAGGACACCCTATTG
TCCGCAATGGAGACTGCCGGGAAAGATGATATGCCAGAGGATGCTGAGAGAAAAGGTCTGGGGACACCGGCCACCCGTGC
CGGTATTTTGGAAAAGCTGGTATCTGCCGGTTTTCTGGAGCGAAAAAAGAACAGAAAAACGGTGCAGCTTCTTCCTTCCC
ACGATGCAGTATCCCTTATCACGGTGCTGCCGGAACAACTGCAATCGCCGCTTCTGACTGCCGAGTGGGAGTACCGCCTG
GGAGAGATCGAGCGCGGGCAGCTTGCCCCGGAGGAGTTTCTGGACGGGATCAGCACCATGCTGAAAGATCTGGTGGGGAC
TTATCAGGTCATCAAGGGAACTGAGTACCTGTTCACTCCGCCCCGCGAGGTGGTGGGCAAATGCCCTCGCTGCGGCGGTG
AAGTTGCAGAACTGCAAAAAGGCTTCTTCTGTCAGAATGATTCTTGCAAATTTGCAATCTGGAAAAACAACAAATGGTGG
GCTGCCAAGAAAAAACAGCCGACCAAAGCTGTGGTGTCTGCGCTGCTGAACGATGGCTGTGTCCGTGTGACGGGGCTATA
TTCGGAGAAAACCGGAAAGACCTACGATGCCGCTGTGGTTTTGGAGGATGATGGACAGTACGCCAACTTCAAGCTGGAAT
TTGACCAGCGGAAAGGAGGCAGCCGATGA

Protein sequence :
MAQHKLVIAEKPSVAQSLAAVIGATVRKDGYLEGNGWRVSWCVGHLAGLADADSYDPKYAKWRYDDLPILPEHWQMVVGK
DKKKQFDILKKLMNAPDVTEVVNACDAGREGEMIFRSVYELAGCKKPMKRLWISSMEDSAIRKGFANLRPGADYDGLRDA
ALCRAKADWLVGINATRLFSVLYHRTLNIGRVMSPTLALIVQREAEIDTFKPIPFYTVALELPGLTVSGERMADKAAAEQ
LKEACQGVNVTIKKVECKEKSEKPPALYDLTTLQRDANRLLGFTAQQTLDYLQSLYEKKLCTYPRTDSRYLTGDMADSLP
VLVNLVANAMPFRKGIAITCDPQTVINDKKVTDHHAVIPTRNLKDADLSALPAGEKAVLELVALRLMCAVAQPHIYSETV
VIAACAGGEFTTKGKTVKHPGWKALEDAYRAKMKDTEPKKEGVEKALPELTEGQTLSVSAAIVKEGKSSLPQHFTEDTLL
SAMETAGKDDMPEDAERKGLGTPATRAGILEKLVSAGFLERKKNRKTVQLLPSHDAVSLITVLPEQLQSPLLTAEWEYRL
GEIERGQLAPEEFLDGISTMLKDLVGTYQVIKGTEYLFTPPREVVGKCPRCGGEVAELQKGFFCQNDSCKFAIWKNNKWW
AAKKKQPTKAVVSALLNDGCVRVTGLYSEKTGKTYDAAVVLEDDGQYANFKLEFDQRKGGSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB-2 NP_815968.1 DNA topoisomerase III Not tested Not named Protein 0.0 56
EFAU085_00720 YP_008394244.1 DNA topoisomerase III Not tested Not named Protein 3e-175 55