Gene Information

Name : RHOM_15375 (RHOM_15375)
Accession : YP_004840113.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 3293111 - 3295210 bp
Length : 2100 bp
Strand : -
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCAGTTGGTGGTTACAGAGAAGCCCAGCGTAGCACAGGCAATTTCCCATGTGATCGGGGCGAAAGAGAGAAAAGACGG
TTACATGGAGGGAAACGGATTTCTCGTTTCATGGTGTGTAGGACATCTGGTAGAGCTGGCACAGCCGGAGATGTATTCAG
AAGCATGGAAAAAATGGAGCTATGAGAGCCTGCCCATGATACCGGAGCAGTGGCAGCATGAAGTGAAAAAGGAAACAGCA
ACGCAGTATAAAATCTTGAAAAATCTGATGCACGATACAAGAGTTGAAAGTGTGGTGTGTGCCACCGATGCCGGACGGGA
GGGAGAACTTATCTTCCGTCTGGTATATGAACAGGCAGGCTGCCGGAAACCAATGAAACGCCTGTGGATTTCATCAATGG
AGGAGAGTGCAATCCGTGACGGGTTTGAAAACTTAAAGCCGGGAAGCGATTATGACAGCCTGTACCAGTCTGCACTTTGC
AGACAGCAGGCAGACTGGCTGGTGGGATTAAATGGTACGAGATTATTTACTGTACTGTATGGCGGAAAGGTATTAAAGGT
GGGCAGAGTACAGACGCCCACCCTTGCCATGCTGGTAGACCGTGAAGTGAAGATTATGAATTTTGAAAAAGAGCAGTATT
ACATGGCTCATATTCTGATGGATGGGATAGATGCCATGACAGAACGGATTGACGATAAGGCAAGGGCAGAAAGTATTGCT
GCAGCGTGTGAAAGTCAGAGTGGAGTGGTTCGTTCCGTTATAAAGGAAAATAAAAGCGTTGCACCACCAAAACTTTATGA
CCTTACCACGCTTCAGCGGGATGCCAACCGTATCTTTGGTTTTACTGCAAAGCAGACATTGGAGTACACCCAGAGCCTTT
ATGAGAAAAAGCTGGTCACTTATCCGAGAACGGACAGCCAGTATTTATCCGATGATATGGAAGAAACTGCAAAAGCGGTA
ATCGGGGCAGTTTATCAGGCGATTCTCTTTGAGGAACAGACCGGAGCAGAGCCGGATATAAAAAGAGTGTTGAACAGTAA
AAAAGTGACCGACCACCATGCAATTATTCCCACCATAGAAATTACAAAGACAGACCTTTCCGCTGTGCCGGAGGGAGAAA
TGAAAATCTTATCCCTTGTCGCTAATCGTCTGTTATGTGCAACCGGGAAAAAGCAGTTGTATGAAACGGTAAAAGCAGAG
TTTTCCTGCGGTGGTTACAGCTTTCATGTATCCGGAAAAACGGTTCTGCAGAACGGGTGGAAAGAATTTGAAGCAGCATT
GAAACGTACCTACCGGGTAGAAAAAACAGATGAGGATAAGGAAGAGAAGAAACTGCCGGAGCTTTCTGAAGGCATGACGT
TTCCAGTTATCCAGACAAAGGTAACAGAGCATTTCACGCAGCCTCCCAAACATTTTACCGAGGACAGCCTGCTTTCTGCG
ATGGAACGTGCCGGAGCAGAGGATATGGGCGATGAGGTGGAACGCAAAGGACTTGGCACACCTGCCACCAGAGCTGACAT
TATTGAAAAGCTGGTCAAAGACGGTTTTGTGAAACGGGAGAAAAAGCAGATGCTTCCCACCGAGGACGGGATGAAGCTCA
TTACTGTTCTGCCGGATATGGTAAAATCCCCGAAGCTTACAGCAGATTGGGAGAATACGCTGACTTTGGTTGAAAAAGGC
GAATACACCATGCAGGAGTTCATGGATGGCATTGAAGATATGGTGCGGGAGCTGGTGCAAACCTACCACAGTATCAGTGA
CGATCAGAAGTCTTTGTTTGGAACGATGCAGGAAGTGCTTGGAAAATGCCCGAAATGCGGCAGCGATGTAGTAAAAGGAA
AATTCGGTGCTTACTGCAAACAAAAATGCGGCATGAATGTGGGTAGGGCAATGGGAGCAACGTTTTCCGATACACAGATG
AAAAGTCTGCTTGAAGGGAAAAAGACCCTTGTGAGAGGATTAAAAGGGAAAAAGGGAAGCTACGATGCGTACCTGATTCC
GGAGGGAATTGAGGATTATTCTTATATCAAAGACGGAAAGGAAATCAAAGGTTCGCAGTACAAATTCAAGATGGAATTTC
CACCGAGAAAAAGCAAGTGA

Protein sequence :
MQLVVTEKPSVAQAISHVIGAKERKDGYMEGNGFLVSWCVGHLVELAQPEMYSEAWKKWSYESLPMIPEQWQHEVKKETA
TQYKILKNLMHDTRVESVVCATDAGREGELIFRLVYEQAGCRKPMKRLWISSMEESAIRDGFENLKPGSDYDSLYQSALC
RQQADWLVGLNGTRLFTVLYGGKVLKVGRVQTPTLAMLVDREVKIMNFEKEQYYMAHILMDGIDAMTERIDDKARAESIA
AACESQSGVVRSVIKENKSVAPPKLYDLTTLQRDANRIFGFTAKQTLEYTQSLYEKKLVTYPRTDSQYLSDDMEETAKAV
IGAVYQAILFEEQTGAEPDIKRVLNSKKVTDHHAIIPTIEITKTDLSAVPEGEMKILSLVANRLLCATGKKQLYETVKAE
FSCGGYSFHVSGKTVLQNGWKEFEAALKRTYRVEKTDEDKEEKKLPELSEGMTFPVIQTKVTEHFTQPPKHFTEDSLLSA
MERAGAEDMGDEVERKGLGTPATRADIIEKLVKDGFVKREKKQMLPTEDGMKLITVLPDMVKSPKLTADWENTLTLVEKG
EYTMQEFMDGIEDMVRELVQTYHSISDDQKSLFGTMQEVLGKCPKCGSDVVKGKFGAYCKQKCGMNVGRAMGATFSDTQM
KSLLEGKKTLVRGLKGKKGSYDAYLIPEGIEDYSYIKDGKEIKGSQYKFKMEFPPRKSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EFAU085_00720 YP_008394244.1 DNA topoisomerase III Not tested Not named Protein 0.0 54
topB-2 NP_815968.1 DNA topoisomerase III Not tested Not named Protein 1e-167 52