Gene Information

Name : RHOM_13490 (RHOM_13490)
Accession : YP_004839736.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 2931644 - 2932309 bp
Length : 666 bp
Strand : -
Note : COG1136 ABC-type antimicrobial peptide transport system, ATPase component

DNA sequence : 
ATGAGCATTTTACAAACAATCGACTTAAAGAAGTATTACGGCACAGAACCAAATATTACTCGTGCCCTTAATGGTGTAAA
TTTTACTGTGGAACAGGGAGAATTTGTTGCCGTAGTTGGAACTTCCGGCAGCGGTAAGTCTACATTGCTTCACATGATGG
GAGGACTTGATACCCCCACTTCCGGCAGCGTGATTGTACGGGGAGAAGAACTCGCAAAAAAGAATGATGATGAATTGACA
ATTTTCCGCCGTCGTAACATCGGATTTATCTTCCAAAATTATAATCTGGTTCCGATTTTGAATGTATATGAAAATATCGT
CCTGCCTGTGGAACTGGATGGCGATACAGTAGACCAGAAATTTATGGACGAAGTTGTGTATATGTTGGCTTTAGAAGATA
AACTGGAAAATATGCCGAACAATCTTTCAGGCGGTCAACAGCAACGTGTAGCGATTGCACGAGCTTTAATTACGAAGCCT
GCGATTATCCTTGCTGATGAACCGACCGGAAATCTTGATAGCAAGACCAGTGCAGATGTGTTAGGGCTTTTGAAGCATAC
CAGCGGAGAATTTAATCAGACCATTGTAATGATTACTCACAACAACGAGATCGCTCAACTCGCAGACCGCATTGTACGGA
TTGAAGATGGTAAAATTGTTGGCTAA

Protein sequence : 
MSILQTIDLKKYYGTEPNITRALNGVNFTVEQGEFVAVVGTSGSGKSTLLHMMGGLDTPTSGSVIVRGEELAKKNDDELT
IFRRRNIGFIFQNYNLVPILNVYENIVLPVELDGDTVDQKFMDEVVYMLALEDKLENMPNNLSGGQQQRVAIARALITKP
AIILADEPTGNLDSKTSADVLGLLKHTSGEFNQTIVMITHNNEIAQLADRIVRIEDGKIVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-37 44
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 7e-38 44
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 7e-38 44
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 7e-38 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHOM_13490 YP_004839736.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 1e-84 80
RHOM_13490 YP_004839736.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 3e-58 55
RHOM_13490 YP_004839736.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 4e-36 44
RHOM_13490 YP_004839736.1 macrolide export ATP-binding/permease MacB NC_012469.1.7685735. Protein 3e-36 41