Gene Information

Name : RHOM_13295 (RHOM_13295)
Accession : YP_004839697.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Resistance
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2890548 - 2891213 bp
Length : 666 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGCAAAATATTTTAGTCGTCGAAGATGATATTGATATTCAAGAAATATTGAATAATTACTTGACTGACGCTGGATATAA
AGTAATTATTGCTTCTGATGGTGTTGCTGGAATTGCTAAATTCAATTCAGAAATTGACCTCGTATTATTGGATATTATGC
TCCCTAAGATTGATGGTTATGGTGTGTGTGAGGTTATTCGGCAAAAGTCAAAAGTTCCCATTATTATGCTGACAGCTCTT
TCGGATGAAGAAAACCAGTTGCGAGGATTTGAACAACAAATTGATGACTATATTCCAAAGCCCTTTTCGCCCAAAATTCT
GCTCTGTAAAATTGCTGCTATTCTACGTCGCGGTTTACAAGATAACATTGATAAGGACATTATCATTTATAAGGATTTAC
GCATGGATATTGAGGGTTTCCATTTGTATTGTAAAGAGCAAGAAGTTATATTAACGCAGAAAGAATTTGATTTACTTCGC
CTTTTACTTGAAAATCAAGGTCGAGTATTTACACGACAAATGCTACTTGATCGGCTATGGGATTTTGATACCTATGTTGA
AGACCGTATTGTTGACAGCCATATCAAAAATCTAAGGAAAAAATTAAACGTAGATTATATAGAAACGATTAGAGGGGTGG
GATATAGAATTGATAAAAGCAATTAA

Protein sequence : 
MQNILVVEDDIDIQEILNNYLTDAGYKVIIASDGVAGIAKFNSEIDLVLLDIMLPKIDGYGVCEVIRQKSKVPIIMLTAL
SDEENQLRGFEQQIDDYIPKPFSPKILLCKIAAILRRGLQDNIDKDIIIYKDLRMDIEGFHLYCKEQEVILTQKEFDLLR
LLLENQGRVFTRQMLLDRLWDFDTYVEDRIVDSHIKNLRKKLNVDYIETIRGVGYRIDKSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 1e-39 44
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-38 42
vanRB YP_001698483.1 regulatory protein Not tested Not named Protein 1e-37 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHOM_13295 YP_004839697.1 DNA-binding response regulator HE999704.1.gene1202. Protein 5e-47 45
RHOM_13295 YP_004839697.1 DNA-binding response regulator AF310956.2.orf0.gene Protein 5e-40 44
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_007622.3794948.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_003923.1003417.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_013450.8614146.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002951.3238224.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_007793.3914065.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002758.1121390.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_010079.5776364.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002952.2859858.p0 Protein 2e-29 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator AE016830.1.gene2255. Protein 7e-39 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator U35369.1.gene1.p01 Protein 7e-39 42
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002952.2859905.p0 Protein 7e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_009782.5559369.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002951.3237708.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_003923.1003749.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002758.1121668.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_009641.5332272.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_013450.8614421.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_007793.3914279.p0 Protein 5e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_007622.3794472.p0 Protein 7e-36 41
RHOM_13295 YP_004839697.1 DNA-binding response regulator NC_002745.1124361.p0 Protein 5e-36 41