Gene Information

Name : RHOM_06955 (RHOM_06955)
Accession : YP_004838438.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Virulence
Product : Na+-transporting two-sector ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1532454 - 1533764 bp
Length : 1311 bp
Strand : +
Note : COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
ATGACACATCAATTTGAAAAATATTTACAACTTGGAGAAAAGACCTACTTCAACCGCCTTGGAAAGGTTGTAAAGATTGT
CGGACTTACGATTGAATCTGTCGGACCGGATGCAAAGTTAAACGATCTCTGCAGAATTGTCATTGACAGAGAGAAAGACC
ACGCGGTGATGGCGGAGGTAGTCGGATTCAGGGATAAGAGACTTTTGCTGATGCCGTTTGAAAATGTGGAAGGCATCGGG
GTAGGATGTATCGTTGAGAATACCGGACATCCGCTTGGGGTGCTTGTCGGGGACGGCGTTCTGGGACACACACTGGACGG
TATCGGAAGACCGACCGACGGCGGAGTCATTGAGGGCGGATGCGAATATCCGGTCGAGGCGGATCCGCCGGATCCGATGA
GCCGTAAGATTATCTCGGAGGTGCTTCCGCTTGGCGTAAAGGCGGTAGACGGGCTGATTACCGTGGGAAAAGGACAGCGT
ATCGGAATCTTTGCGGGTTCCGGTGTCGGAAAGAGCACCCTGCTCGGTATGTTCGCCCGCAATACAAAAGCGGACATTAA
TGTCATTGCCCTGATCGGAGAGCGTGGCCGTGAGGTGCGCGAGTTTATCGAGAGGGATCTCGGGGAAGAGGGAATGAAGC
GTTCCGTCGTCGTGGTGGCGACTTCCGATAAGCCGGCACTGATCCGTAACAAGGCTGCGAAGACGGCGACCGCAATCGCC
GAATATTTCAGGGATCAGGGAAAAGATGTACTGCTGATGATGGACTCTTTGACCCGATTCTCCATGGCACAGCGTGAGAT
CGGCCTCGCGTCCGGAGAACCGCCTGTAACAAGGGGATATCCGCCGAGTGTATACTCGGAGATGCCGAAGCTTCTGGAAC
GTGCCGGTACTTCGGACAAGGGTTCCATCACAGGACTTTACACCGTTCTAGTAGACGGTGATGATTTTAATGAGCCGATT
ACCGATACAGCCCGAAGCATTTTGGACGGACACATCGTGCTTTCCAGAAAACTGGGACACAAGAATCATTACCCGGCGAT
TGATATTTTACAGAGTATTTCCCGTGTTATGAGCGCCATAGCGACCAGCGAGCACAAGGAGCTTGCCGGACGTTTAAAGA
ATGTACTGGCTACTTATAACGAAGCGGAGGATCTGATCAACATCGGAGCTTACAAGAGCGGTTCCAACCGTGAGATTGAC
TATGCGGTTCAGAAGATCAACGCAGTGAATCAGTTCCTGTGCCAGAGGACAGATGAAAAGTTCCTGTTTGACGAGGAAAT
CGATTTATTGAAGAAACTATTTGAAGATTAA

Protein sequence :
MTHQFEKYLQLGEKTYFNRLGKVVKIVGLTIESVGPDAKLNDLCRIVIDREKDHAVMAEVVGFRDKRLLLMPFENVEGIG
VGCIVENTGHPLGVLVGDGVLGHTLDGIGRPTDGGVIEGGCEYPVEADPPDPMSRKIISEVLPLGVKAVDGLITVGKGQR
IGIFAGSGVGKSTLLGMFARNTKADINVIALIGERGREVREFIERDLGEEGMKRSVVVVATSDKPALIRNKAAKTATAIA
EYFRDQGKDVLLMMDSLTRFSMAQREIGLASGEPPVTRGYPPSVYSEMPKLLERAGTSDKGSITGLYTVLVDGDDFNEPI
TDTARSILDGHIVLSRKLGHKNHYPAIDILQSISRVMSAIATSEHKELAGRLKNVLATYNEAEDLINIGAYKSGSNREID
YAVQKINAVNQFLCQRTDEKFLFDEEIDLLKKLFED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-99 55
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-97 53
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-97 53
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-98 53
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-98 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-97 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-98 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-98 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-95 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-95 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-79 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-79 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-79 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-79 50
escN AAC31513.1 L0034 Virulence LEE Protein 1e-79 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-79 50
escN AAC38383.1 EscN Virulence LEE Protein 6e-80 50
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-79 50
unnamed AAL06369.1 EscN Virulence LEE Protein 5e-77 50
escN AAK26715.1 EscN Virulence LEE Protein 3e-78 49
escN AAL57542.1 EscN Virulence LEE Protein 3e-78 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-78 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-78 49
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-79 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-79 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-83 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-82 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 7e-82 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 5e-82 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-82 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-82 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-80 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-71 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 5e-72 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 8e-73 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-73 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 4e-73 46
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-80 46
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 7e-75 46
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 3e-75 46
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-75 46
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 8e-62 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 7e-69 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 7e-69 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-67 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 7e-67 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-67 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 7e-67 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 4e-64 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0048 Protein 1e-98 55
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0390 Protein 2e-104 54
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0192 Protein 2e-103 54
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG2144 Protein 3e-101 52
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0812 Protein 8e-80 50
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0730 Protein 4e-80 50
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG1254 Protein 3e-88 50
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0515 Protein 3e-82 48
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG2459 Protein 3e-67 48
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG2499 Protein 1e-82 47
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG2331 Protein 1e-82 46
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG0555 Protein 3e-67 42
RHOM_06955 YP_004838438.1 Na+-transporting two-sector ATPase VFG1008 Protein 6e-64 41