Gene Information

Name : RHOM_06460 (RHOM_06460)
Accession : YP_004838341.1
Strain : Roseburia hominis A2-183
Genome accession: NC_015977
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 1428104 - 1428769 bp
Length : 666 bp
Strand : +
Note : COG1136 ABC-type antimicrobial peptide transport system, ATPase component

DNA sequence : 
ATGAGCGTTTTACAGGCGATTGATCTGAAAAAGTATTACGGCACAGAGCCGAACATTACCCGCGCCCTTGACGGTGTGAA
CTTCTCCGTGGAGGACGGCGAGTTTGTGGCCGTTGTGGGAACATCCGGCAGCGGCAAGTCCACCCTGCTTCACATGATGG
GCGGGCTGGACACTCCCACCAGCGGAACCGTGATCGTCCGGGGCGAAGAACTGGCAAAGAAGAACGATGAACAGCTTACC
ATCTTTCGCCGCCGCAACATCGGCTTTATCTTCCAGAACTATAACCTTGTTCCTATTCTGAATGTGTATGAGAACATCGT
CCTGCCGGTGGAGCTGGACGGGGACACGGTGGATCAGAAGTTTTTGGACGAGATCGTTCACCTGCTGGGGCTGGAAGATA
AACTGAAAAATATGCCGAATAATCTTTCTGGCGGACAGCAGCAGCGTGTGGCGATTGCCCGCGCTCTGATTACCAAACCG
GCTATTGTGCTGGCCGATGAGCCAACCGGTAACCTTGACAGCAAGACCAGCGCCGAGGTGCTGGGACTTATCAAGCGCAC
CAGCGCGGAGTTCCGGCAAACCGTTGTAATGATTACCCACAATGACGACATAGCCCGCCTTGCAGATCGGATTGTCCGCA
TTGAGGATGGCAGGATTGTGGAATAA

Protein sequence : 
MSVLQAIDLKKYYGTEPNITRALDGVNFSVEDGEFVAVVGTSGSGKSTLLHMMGGLDTPTSGTVIVRGEELAKKNDEQLT
IFRRRNIGFIFQNYNLVPILNVYENIVLPVELDGDTVDQKFLDEIVHLLGLEDKLKNMPNNLSGGQQQRVAIARALITKP
AIVLADEPTGNLDSKTSAEVLGLIKRTSAEFRQTVVMITHNDDIARLADRIVRIEDGRIVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-37 45
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-38 45
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 6e-38 45
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 6e-38 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHOM_06460 YP_004838341.1 macrolide export ATP-binding/permease MacB CP001581.1.gene598.p Protein 2e-83 75
RHOM_06460 YP_004838341.1 macrolide export ATP-binding/permease MacB CP001581.1.gene798.p Protein 3e-57 53
RHOM_06460 YP_004838341.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686878. Protein 3e-35 42
RHOM_06460 YP_004838341.1 macrolide export ATP-binding/permease MacB NC_012469.1.7685735. Protein 1e-35 41