Gene Information

Name : clpB (LRC_02570)
Accession : YP_004831513.1
Strain : Lactobacillus ruminis ATCC 27782
Genome accession: NC_015975
Putative virulence/resistance : Virulence
Product : ATP-binding Clp protease subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 281252 - 283756 bp
Length : 2505 bp
Strand : +
Note : -

DNA sequence :
ATGGACGATTTATATACTGACAGCGCAAAACGCGTAATGGCGATTGCGCAGGAACAGGCAAATTATTTCAGACATCAGGC
AATCGGGACCGAACACTTGCTCTTGGCATTGACGATCGAAGACAAAGGCGTGGCAGGTCAGGTCTTAAAACAAGCGATGG
TGACGCCAGGCGATGTTCGTCGAGAAATCGAACGCTTAGCCGGGTACGGCAATTTGCTGCGTCAGTCGCCAAGCAACTAT
TTGCCGTATTCTCCAAAGGCCAAGTCCGTTTTGGACGAAACCAGGAAACAGGCATTTTTGACTGGGGCCGTCAGAATCGG
GACCGAACATTTTCTGTTAGCATTGTTGAGCGATGAGGACATCCTTTCGTCTCGAATTTTAACCAGTCTGCATGTGGATT
GCAAAAAACTTCGACAAATTCTTTTGCGCAAGCTCGGCATCAGTCAAAGTCAATTGCGTCGCGTGACAAAAAAAGCTGAG
GAACAGCAAGGAAAATCAAAAACGCCGACCTTGGACGAGCTTGGTCGCGACATGACCGAGATGGCTGCTGAAAATATGAT
TGATCCCGTAATCGGACGCGAAAAAGAAGTCAATCGGATTATCCAGATTTTGAGTCGCAGGACAAAAAACAATCCGGTTC
TTTTAGGCGAACCCGGCGTTGGCAAAACGGCGGTTGTTGAGGGCTTGGCACAAGCCATCGTCGAAGGTTGCGTTCCCGAA
AACTTGCTTAATGATCGTTTGATGATGCTTGATATGGGATCGCTTGTTGCCGGCACTAAATATCGCGGCGAATTCGAAGA
TCGCTTGAAAAAGATTCTCGAAGAAGTTTACAACGATGGAAACGTCATTTTATTTATTGATGAGATGCACACGCTCATTG
GTGCGGGTGGTGCTGAGGGAGCAATCGACGCATCCAATATTTTAAAGCCTGCGCTTGCAAGAGGAGAAGTGCAGGTCATC
GGAGCGACGACGCTTGATGAATATCAAAAGTATGTTGAATCAGATCCTGCCTTGGAACGGCGTTTTGCGACCGTTGTCGT
TGAAGAACCGAGCCAAGAGGCGGCATTGGAAATTTTGAAAGGAGTTCGTCCGCGCTACGAAGAACACCATAAGGTAAAAA
TTTCGGATGAGGCCTTGGAAGAAGCCGTACACTTAAGCAGTCGCTATATTACGAAACGCTTTTTGCCCGATAAGGCAATT
GATTTGATGGATGAGGCGGCAGCACGTTTGCGAATCGTTAAAGCAGGAAAAAACGTCAAGCTGCTGGATTTGAACAAAGA
ATTGTCCGAAATCGCCAAGAAACAAGAGCAGGCATTGCTTGACGAAAAATTTGAAGAGGCGGCAAAATTGCGCAACCAGG
CGTTGAAGACAAAAGAAAAGATTGCCAAAATCGAAGAAGCCAAGCGCAAAAAAGACGAAAAGAAGGAGTACGCCGGAATT
GTTTCAGCAGAAGACGTTGCGACGGTCGTTTCCGAGTGGACGGGAGTGCCCGTTACGCAGCTGACAAAAACAGAAAGCGA
ACGTTTGATCAATTTGGAAAAAATTCTGCATAAGCGCGTTGTCGGTCAAGATGAAGCTATCAAGGCCGTGTCGAAAGCAA
TCAGACGTGCAAGAAGCGGTTTGTCTGATCCGACTCGCCCAATCGGGTCATTCATGTTTCTTGGACCAACAGGCGTCGGA
AAGACCGAGCTTGCCAAGGCTTTGGCAGAAGCAATGTTTGGTTCGGAAGACGCCATGATCAGAATCGATATGAGCGAATA
TATGGAGAAATATTCAACCAGTCGTTTGATCGGGGCTCCTCCGGGATACGTCGGGTACGATGAAGGCGGACAGCTGACGG
AAAAGGTCCGCAACAAGCCTTATTCGGTCGTTTTGCTTGATGAAGTCGAAAAAGCCCATCCGGATGTTTTCAACATCTTG
CTTCAAGTGTTGGATGACGGCTATTTGACGGATTCAAAAGGACGAAAGGTCAATTTCAGGAACACGATCATTATTATGAC
GTCTAACCTTGGCGCAACGGCATTACGTGACGAAAAATCGGTCGGATTCGGTGCAACCGATCTCTCAAATGATTATGAGG
CAATGTCTTCCAAAATCAGAGAATCGCTGAAGAAGCATTTCAGGCCTGAATTCTTAAACAGAATTGACGAAATCGTCATC
TTCCATTCACTCGAAAAAGATGAGCTGCACCAAATCGTCAAGTTGATGGCAAAAAACGTCATTAAACGAATTGATGAGCA
AAAGGTCAAGCTCAAGGTTACTCCTGCGGCAATCGAAGTCGTCGCAAAAGCCGGCTTTGATCCCGAATATGGTGCTCGAC
CGATCAGACGGGCGTTGCAGACCGAAGTTGAGGATCTTTTGAGTGACGCATTGCTTCAAGGAAAGATTCAGATCGGAGAC
ACGGTCACGATTGGTGCCAAAAAGGGCAAAATTACTTTGACGGTCAATACGCCTAAAGAAGACAGCGAAAAAAAAGCAGC
CGTTAAAAAACAGACTGCCAAATAG

Protein sequence :
MDDLYTDSAKRVMAIAQEQANYFRHQAIGTEHLLLALTIEDKGVAGQVLKQAMVTPGDVRREIERLAGYGNLLRQSPSNY
LPYSPKAKSVLDETRKQAFLTGAVRIGTEHFLLALLSDEDILSSRILTSLHVDCKKLRQILLRKLGISQSQLRRVTKKAE
EQQGKSKTPTLDELGRDMTEMAAENMIDPVIGREKEVNRIIQILSRRTKNNPVLLGEPGVGKTAVVEGLAQAIVEGCVPE
NLLNDRLMMLDMGSLVAGTKYRGEFEDRLKKILEEVYNDGNVILFIDEMHTLIGAGGAEGAIDASNILKPALARGEVQVI
GATTLDEYQKYVESDPALERRFATVVVEEPSQEAALEILKGVRPRYEEHHKVKISDEALEEAVHLSSRYITKRFLPDKAI
DLMDEAAARLRIVKAGKNVKLLDLNKELSEIAKKQEQALLDEKFEEAAKLRNQALKTKEKIAKIEEAKRKKDEKKEYAGI
VSAEDVATVVSEWTGVPVTQLTKTESERLINLEKILHKRVVGQDEAIKAVSKAIRRARSGLSDPTRPIGSFMFLGPTGVG
KTELAKALAEAMFGSEDAMIRIDMSEYMEKYSTSRLIGAPPGYVGYDEGGQLTEKVRNKPYSVVLLDEVEKAHPDVFNIL
LQVLDDGYLTDSKGRKVNFRNTIIIMTSNLGATALRDEKSVGFGATDLSNDYEAMSSKIRESLKKHFRPEFLNRIDEIVI
FHSLEKDELHQIVKLMAKNVIKRIDEQKVKLKVTPAAIEVVAKAGFDPEYGARPIRRALQTEVEDLLSDALLQGKIQIGD
TVTIGAKKGKITLTVNTPKEDSEKKAAVKKQTAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_004831513.1 ATP-binding Clp protease subunit VFG0079 Protein 0.0 56
clpB YP_004831513.1 ATP-binding Clp protease subunit VFG0080 Protein 5e-145 50