Gene Information

Name : merA (SLG_p_00120)
Accession : YP_004831132.1
Strain :
Genome accession: NC_015974
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 12874 - 14292 bp
Length : 1419 bp
Strand : -
Note : protein synonym:Hg(II) reductase

DNA sequence :
ATGAACGACTGTTGCAACCGCCCCGGGCAGGAAGGATTTGACGTGGCCGTCATCGGCGCGGGTTCTGCCGGGTTCTCCGC
CGCGATCGCCGCTGCCGATCTGGGCGCGAAAGTGGCGCTCGTCGGTCACGGCACGATTGGCGGCACCTGTGTCAATGTTG
GCTGCGTTCCTTCCAAGACGCTGATCCGCGCCGCCGAAGCGGTGCATGGTGGGCTTGCCGCCGCGCGCTTTCCCGGCCTT
GGGGGCGCTGTCCAGATGGATGACTGGTCCGTATTGGCGGCGTCGAAGGACGATCTTGTCACGACGCTGCGCCAAAAAAA
ATATGTCGATCTGCTGCCCGCCTATGACGGTGTGAGCTATATCGAGGGCAAGGCACGCTTTGCCGATGGTGCGCTGATTG
TCGGCGATGCGCCCATGAAGGTCGGCAAGGTCATATTGGCGATGGGTGCGCACGCCGCCGTGCCGCCGATTCCGGGGATG
GACAGCGTGCCCTACCTAACCAGCACATCGGCGCTGGCGCTGGATCGCTTGCCCAAATCGCTGCTGGTGATCGGTGGCGG
GGTGATCGGGGTAGAACTGGGACAGATGTTTTCGCGTCTGGGCGTTGATGTCACCATCTGCTGCCGAAGCCGCCTGCTCC
CCGAAATGGACCCGGAAGTGAGTGCCGCGCTGAAAAACTATTTGGAAGCCGAGGGCGTGCGGGTTTGCGCAGGTGTCGGC
TATCAGCGTATCGCCCAAACACAGAGCGGGGTCGAATTGACCTGCGAGGGGCATTGTGACACCGTCGCGGCGGAACAGGT
GCTCATCGCCACCGGACGCCGACCCAATAGCGACGGGCTTGGGCTGGAGGAGCGCGGCATAGTGCTTGCCCGTAATGGTG
GAATCGTCGTCGATGACCACCTCGAAACGTCGGTTCCAGGCATTTACGCGGCGGGCGATGTAACGGGACGGGACCAGTTC
GTCTACATGGCCGCCTATGGCGCAAAACTGGCCGCGCGCAACGCGGTGACGGGCAACCAATACCGCTACGACAATTCCTC
CATGCCATCCGTCGTCTTCACCGACCCGCAAGTCGCCAGCGCCGGCCTCACTGAAACGACAGCACGGGCGCAAGGCCTGG
ACATCAAGGTTTCGCTGCTCCCGCTCGATGCTGTGCCAAGGGCACTGGCAGCACGCGATACGCGGGGTCTCATCAAACTG
ATTGCCGACAAGGCGAACGACCGTTTGCTGGGCGGCCAGATCATGGCACCCGAAGGCGCGGATTCGATCCAGACACTGGT
GCTGGCGATCAAACACGGCATGACCACCCTGGAATTGGGTGCAACGATATTTCCTTACCTGACCACTGTGGAAGGCCTCA
AACTGGCGGCCCAAACGTTTGATAAGGATGTCGCCAAACTGTCTTGCTGCGCCGGGTGA

Protein sequence :
MNDCCNRPGQEGFDVAVIGAGSAGFSAAIAAADLGAKVALVGHGTIGGTCVNVGCVPSKTLIRAAEAVHGGLAAARFPGL
GGAVQMDDWSVLAASKDDLVTTLRQKKYVDLLPAYDGVSYIEGKARFADGALIVGDAPMKVGKVILAMGAHAAVPPIPGM
DSVPYLTSTSALALDRLPKSLLVIGGGVIGVELGQMFSRLGVDVTICCRSRLLPEMDPEVSAALKNYLEAEGVRVCAGVG
YQRIAQTQSGVELTCEGHCDTVAAEQVLIATGRRPNSDGLGLEERGIVLARNGGIVVDDHLETSVPGIYAAGDVTGRDQF
VYMAAYGAKLAARNAVTGNQYRYDNSSMPSVVFTDPQVASAGLTETTARAQGLDIKVSLLPLDAVPRALAARDTRGLIKL
IADKANDRLLGGQIMAPEGADSIQTLVLAIKHGMTTLELGATIFPYLTTVEGLKLAAQTFDKDVAKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 3e-67 47
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-80 46
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-80 46
merA ABQ57371.1 MerA Not tested SGI1 Protein 9e-70 46
merA AGK07021.1 MerA Not tested SGI1 Protein 9e-70 46
merA AGK07079.1 MerA Not tested SGI1 Protein 9e-70 46
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 4e-68 46
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 3e-68 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-67 45
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 5e-68 45
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 4e-68 45
merA AFG30120.1 MerA Not tested PAGI-2 Protein 4e-68 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_004831132.1 mercuric reductase BAC0651 Protein 7e-81 46
merA YP_004831132.1 mercuric reductase BAC0652 Protein 6e-70 46
merA YP_004831132.1 mercuric reductase BAC0653 Protein 1e-69 45
merA YP_004831132.1 mercuric reductase BAC0650 Protein 3e-69 43