Gene Information

Name : Entas_3851 (Entas_3851)
Accession : YP_004830346.1
Strain : Enterobacter asburiae LF7a
Genome accession: NC_015968
Putative virulence/resistance : Virulence
Product : type VI secretion ATPase, ClpV1 family
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4143126 - 4145720 bp
Length : 2595 bp
Strand : -
Note : TIGRFAM: ATPase, type VI secretion system, ClpV1; PFAM: ATPase associated with various cellular activities, AAA-2; ATPase, AAA-type, core; Clp ATPase, C-terminal; KEGG: aha:AHA_1841 ClpA/ClpB family protein; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGATTAGGATTGAAATAGCCGCTCTTGTAGAACGGTTGCATCCTCTCGTTCGTCGTGCTCTTGAACAGGCCGCGGCGGC
GAGTGTTAATCAGCATGCAACTGAAATTAGTGTAATTCATTTATTAAATGAATTAATTGACGCTCCTCTTTGCGATATTC
GGTTCATATTTGATGAATATGGTATCGATGTCGGGCGCGCAGAATCTTTATTACATGTTAGTCCTCTCGATCGTACTGAC
TATCCGCAGTCATACCCTTCATTTTCACCATTGCTTATCGAATGGTTACAGGATAGCTGGTTACTGGCGTCGACGGAGCT
GAATCATAAAGAGCTGCGTAGCGGAGCCTTGTTTTTGGTTTTGCTGACACATCGTCATCGCTACCTTCCGGTTGATTTTT
GCCGCCTAATCGAAGGAATACACCGTGAGCAGTTGACTGCCAGACTTAATCAAATCACAAAGGATTCCGCTGAGAATAGT
ACTACTGATTCTCCCTTATCCGTAACTACTCCGGTCAATGTTGGTGGAGAGGGCTCGCTACTTTCTCGCTTTACTACCGA
TATAACCGAGGCTGCACGTGAGAACCGGCTCGACCCCGTTTTATGTCGGGATGAAGAGATAGACCTGATGATCGATATTC
TTTGTCGTCGTCGCAAAAACAATCCCATTGTTGTCGGTGAAGCTGGCGTGGGGAAAAGTGCGCTGATTGAAGGATTGGCT
ATTCGCATCGTTGCGAACCAGGTACCAGACCAGCTTAAAGGAACGGTAGTGCTTTCGTTGGATCTGGGGGCGATGCAAGC
GGGAGCCTCAGTTAAAGGAGAGTTTGAGAAGAGATTCAAAGGGATCATGCAGGAAATCTTTGATGCGCCAATGCCAGTCA
TTTTGTTTATTGATGAAGCGCATACTCTGATAGGTGCGGGCAATACGCAGGGAGGGCTGGATGTTTCAAACTTACTCAAG
CCCGCGCTGGCCAGAGGGGAGTTAAAAACAATCGCTGCCACGACCTGGCGGGAGTACAAAAAATACATTGAGAAAGACGC
GGCATTAACCCGACGCTTCCAGCTTGTAAAAGTCAACGAACCTGATCTCGCTCAGGCAACAACCATTCTCCGGGGGTTGG
TGGCTCGTTATGAAATCGCGCATAACGTTCTTGTTGATGACGAGGCGCTGGTCGCTGCAGTTCAATTAAGTGCTCGTTAT
ATTTCAGGCCGACAACTTCCTGATAAAGCTATCGATGTTCTTGATACCGCCTGTGCGCGCTGCGCCATTAACCTGACGGC
TCCACCCCGAGAGTTCACCCGGCTTGAAACCCGATTGAAAGAAACGGAACAAGAAATTCATCATATTGAACGTGAGCAGC
GCATAGGACTAAACGAATATGCGGAACGCCTGGGTGAGCTTTTTTCATTGCGTCAACGTCTCCAGACCGAACGGGAAATC
CTTGAAAAGCAGTGGGATAGCCAGAAGACACTGGTTTCAGAAATAATCTCCTTGCGCCAGTCTCTCCTTAAAGAAGAAGC
ATCTTCCGATACCGCATTGCAATTAGCGGATCGTGAAGCGCAGCTGATTACGTTACAAAAAACGCAGAAGTGCCTTTCAA
CACATGTCGACAAAGATCAGATTTCGGCGGTCATCGCTGAATGGACGGGCGTACCTCTACAGCAGATCACGCAAAATGAG
CTGAAAGTTATCACAGAACTTCCTGATTTCCTTTCTAAAACCATTAAAGGTCAGGATCTTGCCATTGGGCATCTTCATCG
ACATTTATTAACCGCGCGTGCAGATTTAAGGCGAACCGGACGTCCCCTGGGCGCTTTTTTGCTGGTGGGGCCAAGCGGTG
TCGGTAAAACAGAAACCGTGTTACAACTCACCGAACTCCTTTTTGGGGGGAATGCCTGGTTAACGACCATCAATATGTCG
GAATTTCAGGAGAAGCACACTGTTTCAAGGCTTATTGGCTCTCCTCCTGGCTACGTTGGGTACGGCGAAGGCGGGATCCT
GACAGAGGCTATACGTAAAAAGCCCTATTCGGTTGTGCTGCTGGATGAAGTCGAAAAAGCGCATCCAGACGTGCTGAATT
TATTCTATCAAGCCTTTGATAAAGGGGAGATGGCGGATGGCGAAGGGCAGCTTATTGATTGCAAGAATATCGCCTTTTTC
CTGACATCAAATCTGGGTTACCAGACCATCGTTGAAATGAGTGATAGTCCGGAGCAGATACCTGATGCGCTCTATCCAGA
ACTGGCTGCATTCTTCAAACCGGCCTTACTTGCACGTATGGAAACTGTACCTTTCCTCCCGTTAGGCAGTGAGATATTGG
TGTCCATTATTCGCAGCAAGCTTGCTGAGTTGTCGAATAAATTATCCACACGATTTAACGCGGAAATTATTATTGACGAG
GCGGTATATCAGGAGATTTTTGACCGGGCAACCCGCAAAGAAAATGGCGCTCGAATGCTGGAGTCTGTAATAGACGGAGC
ACTACTGCCGCCTGTTTCCATGGTGATTTTACAAAAACTTTCCCACGGCGATACTATCAGCCGTATACATTTTGGCATTG
AGGCGAATAATTTCACCGTTGAGGTCGAAAGCTAA

Protein sequence :
MIRIEIAALVERLHPLVRRALEQAAAASVNQHATEISVIHLLNELIDAPLCDIRFIFDEYGIDVGRAESLLHVSPLDRTD
YPQSYPSFSPLLIEWLQDSWLLASTELNHKELRSGALFLVLLTHRHRYLPVDFCRLIEGIHREQLTARLNQITKDSAENS
TTDSPLSVTTPVNVGGEGSLLSRFTTDITEAARENRLDPVLCRDEEIDLMIDILCRRRKNNPIVVGEAGVGKSALIEGLA
IRIVANQVPDQLKGTVVLSLDLGAMQAGASVKGEFEKRFKGIMQEIFDAPMPVILFIDEAHTLIGAGNTQGGLDVSNLLK
PALARGELKTIAATTWREYKKYIEKDAALTRRFQLVKVNEPDLAQATTILRGLVARYEIAHNVLVDDEALVAAVQLSARY
ISGRQLPDKAIDVLDTACARCAINLTAPPREFTRLETRLKETEQEIHHIEREQRIGLNEYAERLGELFSLRQRLQTEREI
LEKQWDSQKTLVSEIISLRQSLLKEEASSDTALQLADREAQLITLQKTQKCLSTHVDKDQISAVIAEWTGVPLQQITQNE
LKVITELPDFLSKTIKGQDLAIGHLHRHLLTARADLRRTGRPLGAFLLVGPSGVGKTETVLQLTELLFGGNAWLTTINMS
EFQEKHTVSRLIGSPPGYVGYGEGGILTEAIRKKPYSVVLLDEVEKAHPDVLNLFYQAFDKGEMADGEGQLIDCKNIAFF
LTSNLGYQTIVEMSDSPEQIPDALYPELAAFFKPALLARMETVPFLPLGSEILVSIIRSKLAELSNKLSTRFNAEIIIDE
AVYQEIFDRATRKENGARMLESVIDGALLPPVSMVILQKLSHGDTISRIHFGIEANNFTVEVES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 0.0 61
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 0.0 61
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-127 42
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-104 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Entas_3851 YP_004830346.1 type VI secretion ATPase, ClpV1 family VFG2084 Protein 0.0 58
Entas_3851 YP_004830346.1 type VI secretion ATPase, ClpV1 family VFG2076 Protein 1e-141 41
Entas_3851 YP_004830346.1 type VI secretion ATPase, ClpV1 family VFG0079 Protein 8e-103 41