Gene Information

Name : Entas_3338 (Entas_3338)
Accession : YP_004829843.1
Strain : Enterobacter asburiae LF7a
Genome accession: NC_015968
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 3578073 - 3581135 bp
Length : 3063 bp
Strand : +
Note : PFAM: Acriflavin resistance protein; KEGG: ent:Ent638_2568 acriflavin resistance protein

DNA sequence :
ATGGATATCTCTCGTCAGTTTATCAATAACCCCATTCGCGTCTGGCTGACGATCCTGCTGCTGGGTGTGGGGGGCATTTT
CGCCCTGCTCAATATCGGCAGACTGGAAGATCCCGCCTTTACCATCAAAACTGCCGTGGTCATCACCCACTATCCCGGCG
CCTCTGCTCAGCAGGTTGAAGAGGAGGTTACGCTGCCGCTGGAGAATGCGCTTCAGCAATTGCCTTATCTGGACAATGTC
AGCTCCATCTCTTCAAACGGCCTGTCGCAAATCACCGTGAACATTGCCTCACGCTATCATTCGAACGAACTGCCGCAGAT
CTGGGACGAACTGCGCCGTCGCGTGGGCGATGCGTCGCGCCAGTTCCCGCCCGGCGTCGTTACCCCCTTCGTGAATGATG
ATTTTGGCGACGTGTTCGGCTTTTTCTTCGCGATTTCCGGGGATGAATTCAGTAATCCAGAACTGGTGAGATATGCCGAA
CAGCTGCGTCGCGAACTGATTCTTGTCCCCGGCGTCGGTAAGGTTGCCATCGGCGGAGCCATCAGCCAGCAGGTCAACAT
CGATATCTCTCTGACTAAAATGGCCGCGCGCGGCATTACGCTGAACCAGCTTTCCGCCCTGCTCAGCAGGCTTAACGTCG
TTTCCAGCGCCGGAGAAATCAGCTCCGGAACAGAATCCATTCGCCTGCATCCGACCGGTGAGTTCGAAAATCTTGACGAG
CTGGCAGATCTCATCATCACCCCGTCCGGCACCGGGGCAGCAACACGGCTGCGGGATATCGCCACACTGTCGCGCGGGCT
GAACGAATCGCCCGCCAGTATCTATCATGCCAACGGCAGAAAAGCCGTCACTATGGGCGTCTCGTTTATTCCCGGCGTGA
ACGTGATCGACGTTGGCCACGCGCTGGAGGCGAAGCTAAACCAGATGTCGGCGGAAAAACCGGCAGGGATACACATCGAC
CTGTTCTACGATCAGGCCGCCGAAGTGGGCCACTCTGTTAACGGTTTTATCATTAACTTCCTGATGGCGCTGGCGATTGT
CATCGGCGTGCTGCTGATCTTTATGGGCGTGCGCAGCGGGATCATCATCGCCTTTTCTCTCGCGCTTAACGTGCTCGGTA
CGCTGCTGATCATGTATCTGTGGGGCATTGAACTGCAGCGCATCTCGCTCGGTGCCCTGATTATCGCCCTCAGTATGCTG
GTGGATAACGCCATCGTGATTGTTGAAGGGGTGCTGATTGCGCGTCAGCAGGGTTCCCCGCTGTTGACCGCCGTTAACTA
CATCATCCGTCGCTCAGCCCTGCCGCTGCTGGGGGCGACGGTGATCGCCATCCTGGCGTTTGCGCCTATCGGGCTGTCGC
AGGATTCGACCGGGGAATACTGTAAATCCCTGTTCCAGGTGCTGCTGATTTCCCTGATGCTGAGCTGGTTTTCGGCACTC
ACTATCACACCGGTGCTGATCAAGTGGTGGTTGTTTAAAAACGACAGCGCACCGGAAAAAAGTGATGAGTCAGACCCTTA
CGACAAACGCCTCTACCGTCTTTACCAGCGCCTGCTGAATACGCTGCTGCACTGGAAAGCACCGACGCTTATCGTGATGG
CGGCGTTGCTGGCCGCGTCAGTCTGGGGTTTCGGCGCCGTACGGCAAAACTTTTTCCCGTCATCAAATACGCCGATTTTC
TTTGTCGATCTCTGGTTACCCTACGGCACCGATATCAAATGGACCGAGAAAATGACCAGTGATATCGAGAAAACCATTAA
CGGCCAGCCAGGCGTAGAAACCACCGTTTCAACCATTGGCCAGGGCAGTATGCGGTTTATTCTGACCTACAGCGGACAGC
GGCAGTACAGCAACTACGCGCAAATCATGGTGCGCATGGATGACCAGCGCAACATCTCCGCTTTGACGCGCCACGTCGAT
GATTACATCGCCCGAAACTACCCGCAGGTCAATGCCAGTACCAAACGTGTGATGTTTGGCCCCTCCGGCGACAGCGCCAT
TGAGGTGCGCATCAAGGGCCCCGACCCTGACAGACTCCGTCTGATCGCCAGCCAGGTGGACGATATTCTGGCGCGCGACC
CGGCTACAGCAAGCGTAAGAAATGACTGGCAAAACCGCAGCAAGGTGATCCGTCCGCAGTATGTCGCCGCGCTGGGACGC
GAGCTTGGCGTAGATAAGCAGGACGTCGACAACGCGCTGGAGATGAATTTCTCCGGCAGTCGTGCGGGACTGTATCGGGA
AGGCAGCGACCTGCTCCCGGTCGTGGTACGCCCGCCGGAAAGCGAACGACTGGACGCCAATCACCTGAACAACGTGCTGG
TCTGGAGCCAGGCCCGACAGCAGTATATCCCGCTAAGTAACGTCGTCAGCCGCTTTTCGCTGGAGTGGGAAGATCCACTT
ATTCTGCGCCGCGACCGCTCGCGGGTGCTGACGGTTCAGACCGACCCCGATCCGCTTAGCCAGCAAACGTCAGGCGACAT
TCTCGCCCGGGTGAAACCACAGATTGACGCCCTCGCCCTGCCCCACGGCTACAGCATTGAGTGGGGAGGCGATGCAGAAA
ACTCCAGCGAAGCACAGCAGGGGCTCTTCACCACGCTGCCGATCGGGTTCCTGGTGATGTTTGTCATCACCGTTTTGATG
TTCAGCTCGGTGAAAAACGCCGTCGCCATCTGGCTAACCGTGCCTCTGGCGCTGATTGGCGTCACGCCGGGATTCCTGGT
AACCGGTATTCCGTTCGGCTTTATGGCGTTGATTGGTCTGCTAAGCCTGAGCGGGATGCTGATCCGCAACGGCATTGTAC
TGGTGGAAGAGATCGAGCAGCAGAAAGCGCATAAAGACCAGCATGAGGCGATCGTGTATGCCGCCACCTCGCGCCTGCGT
CCTATCTTGCTCACCGCATTTACCACCGTTCTGGGGCTGGCGCCGCTGCTGCTGGATGTTTTCTTCCAGAGCATGGCCGT
TGTGATTATGTTCGGACTTGGGTTTGCTACAATCCTGACGCTGCTGGTACTTCCCGTGATTTATGCGTGCTTCCATCGTA
AGGACAAAGCGGAACAACAATGA

Protein sequence :
MDISRQFINNPIRVWLTILLLGVGGIFALLNIGRLEDPAFTIKTAVVITHYPGASAQQVEEEVTLPLENALQQLPYLDNV
SSISSNGLSQITVNIASRYHSNELPQIWDELRRRVGDASRQFPPGVVTPFVNDDFGDVFGFFFAISGDEFSNPELVRYAE
QLRRELILVPGVGKVAIGGAISQQVNIDISLTKMAARGITLNQLSALLSRLNVVSSAGEISSGTESIRLHPTGEFENLDE
LADLIITPSGTGAATRLRDIATLSRGLNESPASIYHANGRKAVTMGVSFIPGVNVIDVGHALEAKLNQMSAEKPAGIHID
LFYDQAAEVGHSVNGFIINFLMALAIVIGVLLIFMGVRSGIIIAFSLALNVLGTLLIMYLWGIELQRISLGALIIALSML
VDNAIVIVEGVLIARQQGSPLLTAVNYIIRRSALPLLGATVIAILAFAPIGLSQDSTGEYCKSLFQVLLISLMLSWFSAL
TITPVLIKWWLFKNDSAPEKSDESDPYDKRLYRLYQRLLNTLLHWKAPTLIVMAALLAASVWGFGAVRQNFFPSSNTPIF
FVDLWLPYGTDIKWTEKMTSDIEKTINGQPGVETTVSTIGQGSMRFILTYSGQRQYSNYAQIMVRMDDQRNISALTRHVD
DYIARNYPQVNASTKRVMFGPSGDSAIEVRIKGPDPDRLRLIASQVDDILARDPATASVRNDWQNRSKVIRPQYVAALGR
ELGVDKQDVDNALEMNFSGSRAGLYREGSDLLPVVVRPPESERLDANHLNNVLVWSQARQQYIPLSNVVSRFSLEWEDPL
ILRRDRSRVLTVQTDPDPLSQQTSGDILARVKPQIDALALPHGYSIEWGGDAENSSEAQQGLFTTLPIGFLVMFVITVLM
FSSVKNAVAIWLTVPLALIGVTPGFLVTGIPFGFMALIGLLSLSGMLIRNGIVLVEEIEQQKAHKDQHEAIVYAATSRLR
PILLTAFTTVLGLAPLLLDVFFQSMAVVIMFGLGFATILTLLVLPVIYACFHRKDKAEQQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 5e-174 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Entas_3338 YP_004829843.1 acriflavin resistance protein BAC0519 Protein 0.0 51
Entas_3338 YP_004829843.1 acriflavin resistance protein BAC0428 Protein 0.0 50
Entas_3338 YP_004829843.1 acriflavin resistance protein BAC0526 Protein 0.0 48
Entas_3338 YP_004829843.1 acriflavin resistance protein BAC0425 Protein 2e-174 41