Gene Information

Name : Rhom172_2049 (Rhom172_2049)
Accession : YP_004825789.1
Strain : Rhodothermus marinus SG0.5JP17-172
Genome accession: NC_015966
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2336283 - 2337722 bp
Length : 1440 bp
Strand : -
Note : TIGRFAM: Pyruvate kinase; KEGG: rmr:Rmar_0833 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta

DNA sequence :
ATGACACGCCGCACGAAGATCGTCTGTACGCTGGGACCGGCCTCGTCGGATCGCGAGACCATCCGAAAGCTCATTGAGGC
CGGCATGGATGTGGCCCGGTTGAATTTTTCGCACGGCAACCATGAGGAGCATCGCCGCCGCATCGAAATCGTCCGGGAGG
AGGCGCGCAAGCTCGGGCGCGACGTGGCCATCCTGCAGGATCTGCAGGGCCCCAAGATCCGCCTCGGTGAAGTGGCCGAG
GGCGGCATTCTGATCCACGAGGGGCAGCGGCTGGTCCTGACGGCCCATCCTGAGCGGGCCGACGGGCAGACCCGCATCTT
CGTGAACTATCCCACGCTGGCGCAGGACGTGGAGCCCGGCGGCCGCATTCTGCTGGACGACGGCCTGCTGGAATTGAAAA
TCGTGGACGTGGAAGGCGAGGACGTGATTACGGAGGTGGTGGTTGGCGGACCGCTTCGCTCGCGCAAGGGCGTCAACCTG
CCCCACTTGCGCAACTCCACGCCGTCGCTTACTGAAAAGGACCTGCGCGATCTGGAGTTCGGCCTGCAGATGGAAGTGGA
CCTGATCGCGCTTTCGTTCGTGCGAAGCGAAACAGACGTGGCCGATCTGATGCGCCGCGTGCGGGACTCCGGCAAAGAAG
TGCGCGTGATCGCCAAGATCGAAAAGCCGGAAGCGGTGGCCAAGATCGATCAGATTCTGGCGCAGGCCGACGGGATCATG
GTGGCGCGCGGTGATCTGGGGATCGAAATGCCGCTGGCTGAGGTGCCGGCCGTGCAGAAACGCATCATCCGGAAGTGTCT
GGCCGCAGCCAAGCCGGTCATCACGGCCACGCAGATGCTCGAAAGCATGATCGAGAACCCACGGCCCACGCGTGCCGAGG
CCAGCGACGTGGCCAATGCGGTGCTGGACGGCAGCGACGCGCTGATGCTTTCGGGCGAGACGGCCACCGGTAAATATCCG
GTGCGCGTGGTGCAGGTGATGGACGAGATCATCCGGCAGGCCGAACGCTTCCGGCGCGAGATTCGCGAAAGTCGGGGCCA
CGGGCTGCACATCCCGAAAGGCGCCGACGAGGCCGAGTCGGTCACCGAAGCCATTGGCTATACGGCCTGTCAGCTTGCCG
AGCAGGTGGGCGCCGTGGCGATCGCCTGCCTGACGGCCACGGGCAGCACGGCCCGTATGATCGCACGCCACCGGCCGCCC
GTTCCGGTCTATGCCTTCACCGACAATCCCCGCGTTGTCCCCCAGCTCAGCCTGCTCTGGGGCACGCGCGCCTTTTCGAT
TCCCTTTCAGCGCGACACGGACCAGGGCGTGCAACTGGTGCACCGGATTCTAAAAGAACAGGGACTGGTCAGGCCGGGCG
ATCTGGTGGTCATCACGGCCGGGATGCCGCTGCCGGCCAAAGGACGCACCAACATGGTGCACGTCAGTCGGATCGAGTAA

Protein sequence :
MTRRTKIVCTLGPASSDRETIRKLIEAGMDVARLNFSHGNHEEHRRRIEIVREEARKLGRDVAILQDLQGPKIRLGEVAE
GGILIHEGQRLVLTAHPERADGQTRIFVNYPTLAQDVEPGGRILLDDGLLELKIVDVEGEDVITEVVVGGPLRSRKGVNL
PHLRNSTPSLTEKDLRDLEFGLQMEVDLIALSFVRSETDVADLMRRVRDSGKEVRVIAKIEKPEAVAKIDQILAQADGIM
VARGDLGIEMPLAEVPAVQKRIIRKCLAAAKPVITATQMLESMIENPRPTRAEASDVANAVLDGSDALMLSGETATGKYP
VRVVQVMDEIIRQAERFRREIRESRGHGLHIPKGADEAESVTEAIGYTACQLAEQVGAVAIACLTATGSTARMIARHRPP
VPVYAFTDNPRVVPQLSLLWGTRAFSIPFQRDTDQGVQLVHRILKEQGLVRPGDLVVITAGMPLPAKGRTNMVHVSRIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-68 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-68 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 41
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 7e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rhom172_2049 YP_004825789.1 pyruvate kinase VFG0479 Protein 9e-69 41